ID Q2NKT5_BOVIN Unreviewed; 96 AA.
AC Q2NKT5;
DT 07-FEB-2006, integrated into UniProtKB/TrEMBL.
DT 07-FEB-2006, sequence version 1.
DT 27-MAR-2024, entry version 110.
DE RecName: Full=Protein transport protein Sec61 subunit beta {ECO:0000256|PIRNR:PIRNR006398};
GN Name=SEC61B {ECO:0000313|EMBL:AAI11653.1,
GN ECO:0000313|Ensembl:ENSBTAP00000003190.3,
GN ECO:0000313|VGNC:VGNC:49570};
OS Bos taurus (Bovine).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Laurasiatheria; Artiodactyla; Ruminantia; Pecora; Bovidae;
OC Bovinae; Bos.
OX NCBI_TaxID=9913 {ECO:0000313|EMBL:AAI11653.1};
RN [1] {ECO:0000313|EMBL:AAI11653.1}
RP NUCLEOTIDE SEQUENCE.
RC STRAIN=Hereford {ECO:0000313|EMBL:AAI11653.1};
RC TISSUE=Testis {ECO:0000313|EMBL:AAI11653.1};
RA Moore S., Alexander L., Brownstein M., Guan L., Lobo S., Meng Y.,
RA Tanaguchi M., Wang Z., Yu J., Prange C., Schreiber K., Shenmen C.,
RA Wagner L., Bala M., Barbazuk S., Barber S., Babakaiff R., Beland J.,
RA Chun E., Del Rio L., Gibson S., Hanson R., Kirkpatrick R., Liu J.,
RA Matsuo C., Mayo M., Santos R.R., Stott J., Tsai M., Wong D., Siddiqui A.,
RA Holt R., Jones S.J., Marra M.A.;
RL Submitted (JAN-2006) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|Ensembl:ENSBTAP00000003190.3, ECO:0000313|Proteomes:UP000009136}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Hereford {ECO:0000313|Ensembl:ENSBTAP00000003190.3,
RC ECO:0000313|Proteomes:UP000009136};
RA Rosen B.D., Bickhart D.M., Koren S., Schnabel R.D., Hall R., Zimin A.,
RA Dreischer C., Schultheiss S., Schroeder S.G., Elsik C.G., Couldrey C.,
RA Liu G.E., Van Tassell C.P., Phillippy A.M., Smith T.P.L., Medrano J.F.;
RT "ARS-UCD1.2.";
RL Submitted (MAR-2018) to the EMBL/GenBank/DDBJ databases.
RN [3] {ECO:0000313|Ensembl:ENSBTAP00000003190.3}
RP IDENTIFICATION.
RC STRAIN=Hereford {ECO:0000313|Ensembl:ENSBTAP00000003190.3};
RG Ensembl;
RL Submitted (NOV-2023) to UniProtKB.
CC -!- FUNCTION: Necessary for protein translocation in the endoplasmic
CC reticulum. {ECO:0000256|PIRNR:PIRNR006398}.
CC -!- SUBCELLULAR LOCATION: Endoplasmic reticulum membrane
CC {ECO:0000256|ARBA:ARBA00004389}; Single-pass membrane protein
CC {ECO:0000256|ARBA:ARBA00004389}. Membrane
CC {ECO:0000256|ARBA:ARBA00004167}; Single-pass membrane protein
CC {ECO:0000256|ARBA:ARBA00004167}.
CC -!- SIMILARITY: Belongs to the SEC61-beta family.
CC {ECO:0000256|ARBA:ARBA00006103, ECO:0000256|PIRNR:PIRNR006398}.
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DR EMBL; BC111652; AAI11653.1; -; mRNA.
DR RefSeq; NP_001068760.1; NM_001075292.2.
DR PaxDb; 9913-ENSBTAP00000003190; -.
DR Ensembl; ENSBTAT00000003190.4; ENSBTAP00000003190.3; ENSBTAG00000002457.4.
DR GeneID; 506986; -.
DR KEGG; bta:506986; -.
DR CTD; 10952; -.
DR VEuPathDB; HostDB:ENSBTAG00000002457; -.
DR VGNC; VGNC:49570; SEC61B.
DR eggNOG; KOG3457; Eukaryota.
DR GeneTree; ENSGT00390000003561; -.
DR HOGENOM; CLU_133423_4_0_1; -.
DR OMA; TNSGGMW; -.
DR OrthoDB; 9185at2759; -.
DR TreeFam; TF313144; -.
DR Proteomes; UP000009136; Chromosome 8.
DR Bgee; ENSBTAG00000002457; Expressed in prostate gland and 107 other cell types or tissues.
DR GO; GO:0031205; C:endoplasmic reticulum Sec complex; IDA:UniProtKB.
DR GO; GO:0005784; C:Sec61 translocon complex; IEA:UniProtKB-UniRule.
DR GO; GO:0006886; P:intracellular protein transport; IEA:InterPro.
DR InterPro; IPR030671; Sec61-beta/Sbh.
DR InterPro; IPR016482; SecG/Sec61-beta/Sbh.
DR PANTHER; PTHR13509:SF3; PROTEIN TRANSPORT PROTEIN SEC61 SUBUNIT BETA; 1.
DR PANTHER; PTHR13509; SEC61 SUBUNIT BETA; 1.
DR Pfam; PF03911; Sec61_beta; 1.
DR PIRSF; PIRSF006398; Sec61_beta_euk; 1.
PE 1: Evidence at protein level;
KW Endoplasmic reticulum {ECO:0000256|ARBA:ARBA00022824,
KW ECO:0000256|PIRNR:PIRNR006398};
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|PIRNR:PIRNR006398};
KW Protein transport {ECO:0000256|ARBA:ARBA00022927,
KW ECO:0000256|PIRNR:PIRNR006398};
KW Proteomics identification {ECO:0007829|PeptideAtlas:Q2NKT5};
KW Reference proteome {ECO:0000313|Proteomes:UP000009136};
KW Translocation {ECO:0000256|ARBA:ARBA00023010,
KW ECO:0000256|PIRNR:PIRNR006398};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius};
KW Transport {ECO:0000256|ARBA:ARBA00022448, ECO:0000256|PIRNR:PIRNR006398}.
FT TRANSMEM 71..90
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT REGION 1..54
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 31..54
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 96 AA; 9944 MW; 4204840D3F76AB0C CRC64;
MPGPAPSGTN VGSSGRSPSK AVAARAAGST VRQRKNASCG TRSAGRTTSA GTGGMWRFYT
EDSPGLKVGP VPVLVMSLLF IASVFMLHIW GKYTRS
//
