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Database: UniProt
Entry: Q2NQB2
LinkDB: Q2NQB2
Original site: Q2NQB2 
ID   RHLB_SODGM              Reviewed;         415 AA.
AC   Q2NQB2;
DT   20-MAY-2008, integrated into UniProtKB/Swiss-Prot.
DT   07-FEB-2006, sequence version 1.
DT   16-OCT-2019, entry version 89.
DE   RecName: Full=ATP-dependent RNA helicase RhlB {ECO:0000255|HAMAP-Rule:MF_00661};
DE            EC=3.6.4.13 {ECO:0000255|HAMAP-Rule:MF_00661};
GN   Name=rhlB {ECO:0000255|HAMAP-Rule:MF_00661}; OrderedLocusNames=SG2388;
OS   Sodalis glossinidius (strain morsitans).
OC   Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
OC   Pectobacteriaceae; Sodalis.
OX   NCBI_TaxID=343509;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=morsitans;
RX   PubMed=16365377; DOI=10.1101/gr.4106106;
RA   Toh H., Weiss B.L., Perkin S.A.H., Yamashita A., Oshima K.,
RA   Hattori M., Aksoy S.;
RT   "Massive genome erosion and functional adaptations provide insights
RT   into the symbiotic lifestyle of Sodalis glossinidius in the tsetse
RT   host.";
RL   Genome Res. 16:149-156(2006).
CC   -!- FUNCTION: DEAD-box RNA helicase involved in RNA degradation. Has
CC       RNA-dependent ATPase activity and unwinds double-stranded RNA.
CC       {ECO:0000255|HAMAP-Rule:MF_00661}.
CC   -!- CATALYTIC ACTIVITY:
CC       Reaction=ATP + H2O = ADP + H(+) + phosphate; Xref=Rhea:RHEA:13065,
CC         ChEBI:CHEBI:15377, ChEBI:CHEBI:15378, ChEBI:CHEBI:30616,
CC         ChEBI:CHEBI:43474, ChEBI:CHEBI:456216; EC=3.6.4.13;
CC         Evidence={ECO:0000255|HAMAP-Rule:MF_00661};
CC   -!- SUBUNIT: Component of the RNA degradosome, which is a multiprotein
CC       complex involved in RNA processing and mRNA degradation.
CC       {ECO:0000255|HAMAP-Rule:MF_00661}.
CC   -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000255|HAMAP-Rule:MF_00661}.
CC   -!- SIMILARITY: Belongs to the DEAD box helicase family. RhlB
CC       subfamily. {ECO:0000255|HAMAP-Rule:MF_00661}.
DR   EMBL; AP008232; BAE75663.1; -; Genomic_DNA.
DR   RefSeq; WP_011412194.1; NC_007712.1.
DR   SMR; Q2NQB2; -.
DR   STRING; 343509.SG2388; -.
DR   EnsemblBacteria; BAE75663; BAE75663; SG2388.
DR   KEGG; sgl:SG2388; -.
DR   eggNOG; ENOG4105C1J; Bacteria.
DR   eggNOG; COG0513; LUCA.
DR   HOGENOM; HOG000268807; -.
DR   KO; K03732; -.
DR   OMA; TRFHDFK; -.
DR   OrthoDB; 626183at2; -.
DR   BioCyc; SGLO343509:SGP1_RS21695-MONOMER; -.
DR   Proteomes; UP000001932; Chromosome.
DR   GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-UniRule.
DR   GO; GO:0003723; F:RNA binding; IEA:UniProtKB-UniRule.
DR   GO; GO:0003724; F:RNA helicase activity; IEA:UniProtKB-UniRule.
DR   GO; GO:0006401; P:RNA catabolic process; IEA:UniProtKB-UniRule.
DR   HAMAP; MF_00661; DEAD_helicase_RhlB; 1.
DR   InterPro; IPR011545; DEAD/DEAH_box_helicase_dom.
DR   InterPro; IPR014001; Helicase_ATP-bd.
DR   InterPro; IPR001650; Helicase_C.
DR   InterPro; IPR027417; P-loop_NTPase.
DR   InterPro; IPR000629; RNA-helicase_DEAD-box_CS.
DR   InterPro; IPR023554; RNA_helicase_ATP-dep_RhlB.
DR   InterPro; IPR014014; RNA_helicase_DEAD_Q_motif.
DR   Pfam; PF00270; DEAD; 1.
DR   Pfam; PF00271; Helicase_C; 1.
DR   SMART; SM00487; DEXDc; 1.
DR   SMART; SM00490; HELICc; 1.
DR   SUPFAM; SSF52540; SSF52540; 1.
DR   PROSITE; PS00039; DEAD_ATP_HELICASE; 1.
DR   PROSITE; PS51192; HELICASE_ATP_BIND_1; 1.
DR   PROSITE; PS51194; HELICASE_CTER; 1.
DR   PROSITE; PS51195; Q_MOTIF; 1.
PE   3: Inferred from homology;
KW   ATP-binding; Complete proteome; Cytoplasm; Helicase; Hydrolase;
KW   Nucleotide-binding; Reference proteome; RNA-binding.
FT   CHAIN         1    415       ATP-dependent RNA helicase RhlB.
FT                                /FTId=PRO_1000082875.
FT   DOMAIN       40    219       Helicase ATP-binding. {ECO:0000255|HAMAP-
FT                                Rule:MF_00661}.
FT   DOMAIN      245    390       Helicase C-terminal. {ECO:0000255|HAMAP-
FT                                Rule:MF_00661}.
FT   NP_BIND      53     60       ATP. {ECO:0000255|HAMAP-Rule:MF_00661}.
FT   MOTIF         9     37       Q motif.
FT   MOTIF       165    168       DEAD box.
SQ   SEQUENCE   415 AA;  46334 MW;  18F20C27D58E4C88 CRC64;
     MSKTHLTEKK FSDFALYPPI VEVLDSKGFN NCTPIQALTL PTTLAGKDVA GQAQTGTGKT
     LAFLTATFHH LLTHPAAEGR QTNQPRALIM APTRELAVQI HSDAEPLAQA TGLKMGLAYG
     GDGYDKQLKV LEAGVDILVG TTGRLIDYTK QNYVNMSAIQ VVVLDEADRM FDLGFIKDIR
     WLFRRMPAAA GRLNMLFSAT LSYRVRELAF EHMNNAEYVE VEPLQKTGHR IQEELFYPSN
     EEKMRLLQTL IEEEWPDRCI IFANTKHRCE DIWGHLAADG HRVGLLTGDV SQKRRLRILE
     KFTQGALDIL VATDVAARGL HIPSVTHVFN YDLPDDCEDY VHRIGRTGRA GESGCSISLA
     CEEYALNLTA IESYIGHQIP VSKYNSDALL TDLPAPKRLT RRRSGAPRHN RKRPG
//
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