ID Q2NQT1_SODGM Unreviewed; 352 AA.
AC Q2NQT1;
DT 07-FEB-2006, integrated into UniProtKB/TrEMBL.
DT 07-FEB-2006, sequence version 1.
DT 27-MAR-2024, entry version 95.
DE SubName: Full=Polyketide synthase {ECO:0000313|EMBL:BAE75494.1};
GN OrderedLocusNames=SG2219 {ECO:0000313|EMBL:BAE75494.1};
OS Sodalis glossinidius (strain morsitans).
OC Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
OC Bruguierivoracaceae; Sodalis.
OX NCBI_TaxID=343509 {ECO:0000313|EMBL:BAE75494.1, ECO:0000313|Proteomes:UP000001932};
RN [1] {ECO:0000313|EMBL:BAE75494.1, ECO:0000313|Proteomes:UP000001932}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=morsitans {ECO:0000313|Proteomes:UP000001932};
RX PubMed=16365377; DOI=10.1101/gr.4106106;
RA Toh H., Weiss B.L., Perkin S.A.H., Yamashita A., Oshima K., Hattori M.,
RA Aksoy S.;
RT "Massive genome erosion and functional adaptations provide insights into
RT the symbiotic lifestyle of Sodalis glossinidius in the tsetse host.";
RL Genome Res. 16:149-156(2006).
CC -!- SIMILARITY: Belongs to the thiolase-like superfamily. Chalcone/stilbene
CC synthases family. {ECO:0000256|ARBA:ARBA00005531}.
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DR EMBL; AP008232; BAE75494.1; -; Genomic_DNA.
DR AlphaFoldDB; Q2NQT1; -.
DR STRING; 343509.SG2219; -.
DR KEGG; sgl:SG2219; -.
DR eggNOG; COG3424; Bacteria.
DR HOGENOM; CLU_034992_0_0_6; -.
DR BioCyc; SGLO343509:SGP1_RS20425-MONOMER; -.
DR Proteomes; UP000001932; Chromosome.
DR GO; GO:0016747; F:acyltransferase activity, transferring groups other than amino-acyl groups; IEA:InterPro.
DR GO; GO:0009058; P:biosynthetic process; IEA:InterPro.
DR CDD; cd00831; CHS_like; 1.
DR Gene3D; 3.40.47.10; -; 2.
DR InterPro; IPR012328; Chalcone/stilbene_synt_C.
DR InterPro; IPR001099; Chalcone/stilbene_synt_N.
DR InterPro; IPR011141; Polyketide_synthase_type-III.
DR InterPro; IPR016039; Thiolase-like.
DR PANTHER; PTHR11877:SF99; 1,3,6,8-TETRAHYDROXYNAPHTHALENE SYNTHASE; 1.
DR PANTHER; PTHR11877; HYDROXYMETHYLGLUTARYL-COA SYNTHASE; 1.
DR Pfam; PF02797; Chal_sti_synt_C; 1.
DR Pfam; PF00195; Chal_sti_synt_N; 1.
DR PIRSF; PIRSF000451; PKS_III; 1.
DR SUPFAM; SSF53901; Thiolase-like; 1.
PE 3: Inferred from homology;
KW Acyltransferase {ECO:0000256|ARBA:ARBA00023315};
KW Transferase {ECO:0000256|ARBA:ARBA00023315}.
FT DOMAIN 30..206
FT /note="Chalcone/stilbene synthase N-terminal"
FT /evidence="ECO:0000259|Pfam:PF00195"
FT DOMAIN 215..346
FT /note="Chalcone/stilbene synthase C-terminal"
FT /evidence="ECO:0000259|Pfam:PF02797"
FT ACT_SITE 143
FT /note="Acyl-thioester intermediate"
FT /evidence="ECO:0000256|PIRSR:PIRSR000451-1"
SQ SEQUENCE 352 AA; 38681 MW; 2C73EA702A9CD31B CRC64;
MEIVNIPTLH KPAVYLPEYI ISQQDTINLA RTNFKDNPNL EKSIELIINT GVMKRHIIQP
IKLATLHPGF GYRNAVFEYE SKRLVPSVVE QALNNAAASA SQIAAIIYVS CSGFLMPSLT
AWLINHMGLP DNTMQLPIAQ LGCATGGSAI NRAHDYVLAH PGSNVLIISC EFCSLSYQPT
DGDVGSLLSD RLFGDAISAA VVTAEPGEGL SLERNASYLI PETDEWIRYQ VKDTGFHFRL
DKRVPGTMKP LAPVMRQLAC DHGWDIENLA YCIIHAGGQR ILDDLAKYLR VDLEQFSFSR
DTLANCGNIA SSVVFEAYRR MHEKGIFARG GKAIIAGFGP GITAEMSLSQ WI
//
