ID Q2NVZ2_SODGM Unreviewed; 492 AA.
AC Q2NVZ2;
DT 07-FEB-2006, integrated into UniProtKB/TrEMBL.
DT 07-FEB-2006, sequence version 1.
DT 27-MAR-2024, entry version 97.
DE SubName: Full=Alanine-sodium transport protein {ECO:0000313|EMBL:BAE73683.1};
DE SubName: Full=Amino-acid carrier protein AlsT {ECO:0000313|EMBL:CRL44091.1};
GN Name=alsT {ECO:0000313|EMBL:CRL44091.1};
GN OrderedLocusNames=SG0408 {ECO:0000313|EMBL:BAE73683.1};
GN ORFNames=SGGMMB4_01004 {ECO:0000313|EMBL:CRL44091.1};
OS Sodalis glossinidius (strain morsitans).
OC Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
OC Bruguierivoracaceae; Sodalis.
OX NCBI_TaxID=343509 {ECO:0000313|EMBL:BAE73683.1, ECO:0000313|Proteomes:UP000001932};
RN [1] {ECO:0000313|EMBL:BAE73683.1, ECO:0000313|Proteomes:UP000001932}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=morsitans {ECO:0000313|Proteomes:UP000001932}, and Morsitans
RC {ECO:0000313|EMBL:BAE73683.1};
RX PubMed=16365377; DOI=10.1101/gr.4106106;
RA Toh H., Weiss B.L., Perkin S.A.H., Yamashita A., Oshima K., Hattori M.,
RA Aksoy S.;
RT "Massive genome erosion and functional adaptations provide insights into
RT the symbiotic lifestyle of Sodalis glossinidius in the tsetse host.";
RL Genome Res. 16:149-156(2006).
RN [2] {ECO:0000313|EMBL:CRL44091.1, ECO:0000313|Proteomes:UP000245838}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=B4 {ECO:0000313|EMBL:CRL44091.1}, and morsitans
RC {ECO:0000313|Proteomes:UP000245838};
RA Goodhead I.;
RL Submitted (MAY-2015) to the EMBL/GenBank/DDBJ databases.
CC -!- SUBCELLULAR LOCATION: Cell inner membrane
CC {ECO:0000256|RuleBase:RU363064}; Multi-pass membrane protein
CC {ECO:0000256|RuleBase:RU363064}. Membrane
CC {ECO:0000256|ARBA:ARBA00004141}; Multi-pass membrane protein
CC {ECO:0000256|ARBA:ARBA00004141}.
CC -!- SIMILARITY: Belongs to the alanine or glycine:cation symporter (AGCS)
CC (TC 2.A.25) family. {ECO:0000256|ARBA:ARBA00009261,
CC ECO:0000256|RuleBase:RU363064}.
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DR EMBL; AP008232; BAE73683.1; -; Genomic_DNA.
DR EMBL; LN854557; CRL44091.1; -; Genomic_DNA.
DR RefSeq; WP_011410271.1; NZ_LN854557.1.
DR STRING; 343509.SG0408; -.
DR KEGG; sgl:SG0408; -.
DR eggNOG; COG1115; Bacteria.
DR HOGENOM; CLU_024867_0_1_6; -.
DR OrthoDB; 9806926at2; -.
DR BioCyc; SGLO343509:SGP1_RS03775-MONOMER; -.
DR Proteomes; UP000001932; Chromosome.
DR Proteomes; UP000245838; Chromosome sggmmb4_Chromosome.
DR GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0005283; F:amino acid:sodium symporter activity; IEA:InterPro.
DR Gene3D; 1.20.1740.10; Amino acid/polyamine transporter I; 1.
DR InterPro; IPR001463; Na/Ala_symport.
DR NCBIfam; TIGR00835; agcS; 1.
DR PANTHER; PTHR30330; AGSS FAMILY TRANSPORTER, SODIUM-ALANINE; 1.
DR PANTHER; PTHR30330:SF1; AMINO-ACID CARRIER PROTEIN ALST; 1.
DR Pfam; PF01235; Na_Ala_symp; 1.
DR PRINTS; PR00175; NAALASMPORT.
DR PROSITE; PS00873; NA_ALANINE_SYMP; 1.
PE 3: Inferred from homology;
KW Cell inner membrane {ECO:0000256|RuleBase:RU363064};
KW Cell membrane {ECO:0000256|ARBA:ARBA00022475};
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|RuleBase:RU363064};
KW Symport {ECO:0000256|RuleBase:RU363064};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692,
KW ECO:0000256|RuleBase:RU363064};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|RuleBase:RU363064};
KW Transport {ECO:0000256|ARBA:ARBA00022448, ECO:0000256|RuleBase:RU363064}.
FT TRANSMEM 16..34
FT /note="Helical"
FT /evidence="ECO:0000256|RuleBase:RU363064"
FT TRANSMEM 68..87
FT /note="Helical"
FT /evidence="ECO:0000256|RuleBase:RU363064"
FT TRANSMEM 137..159
FT /note="Helical"
FT /evidence="ECO:0000256|RuleBase:RU363064"
FT TRANSMEM 179..199
FT /note="Helical"
FT /evidence="ECO:0000256|RuleBase:RU363064"
FT TRANSMEM 206..224
FT /note="Helical"
FT /evidence="ECO:0000256|RuleBase:RU363064"
FT TRANSMEM 297..319
FT /note="Helical"
FT /evidence="ECO:0000256|RuleBase:RU363064"
FT TRANSMEM 354..371
FT /note="Helical"
FT /evidence="ECO:0000256|RuleBase:RU363064"
FT TRANSMEM 392..413
FT /note="Helical"
FT /evidence="ECO:0000256|RuleBase:RU363064"
FT TRANSMEM 419..439
FT /note="Helical"
FT /evidence="ECO:0000256|RuleBase:RU363064"
FT REGION 473..492
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 492 AA; 52631 MW; 56FAA9A06800FDD1 CRC64;
MAELLNFINN LLRDSLLIYL LLGTSIWFTL RTGFIQIRHF CHTFTILKDS GTRGGGGISP
FQALCTSLAA RIGCGNLMGV AIALILGGPG AIFWMWLAAL IGMATAFAES TLAQLYKIRD
DRGNACGGPA WYMANGLGLR WMGTLFTLFL LAGYGGFFSA VQANAITLSA QQLSGMGRWP
ITLALLILSA AAIFGGLRAI ARLTQWLVPI IGIIYLLLAG WVVVHHWRQL ATVAALVFNS
AFGLPEAASG LVGYGLAQAI FQGVQRGLFS NEAGTGSAPN IAAAAAPWPP HPASQGYIQM
LAVFIDTLVI CSATAAIILT SGTLEHAHAD LHGIALINQA LATVTGHWSM PLLMALVFVF
SFAAIIGNYA YAESSLRFFV LQPMKLKWLL RLLTLTMILF GCVAEVSVVW RLADLAMGLM
TITNLIALLL LSPVVLMLAN DYNSQRAIGK LPTFYAVNFP AIAPQLAPDL WGRPTASHQE
SSSTAAPKPL DR
//
