ID Q2RGP5_MOOTA Unreviewed; 338 AA.
AC Q2RGP5;
DT 24-JAN-2006, integrated into UniProtKB/TrEMBL.
DT 24-JAN-2006, sequence version 1.
DT 27-MAR-2024, entry version 85.
DE SubName: Full=Methyltransferase MtaA/CmuA {ECO:0000313|EMBL:ABC20394.1};
GN OrderedLocusNames=Moth_2102 {ECO:0000313|EMBL:ABC20394.1};
OS Moorella thermoacetica (strain ATCC 39073 / JCM 9320).
OC Bacteria; Bacillota; Clostridia; Moorellales; Moorellaceae; Moorella.
OX NCBI_TaxID=264732 {ECO:0000313|EMBL:ABC20394.1};
RN [1] {ECO:0000313|EMBL:ABC20394.1}
RP NUCLEOTIDE SEQUENCE.
RC STRAIN=ATCC 39073 {ECO:0000313|EMBL:ABC20394.1};
RG US DOE Joint Genome Institute;
RA Copeland A., Lucas S., Lapidus A., Barry K., Detter J.C., Glavina T.,
RA Hammon N., Israni S., Pitluck S., Chertkov O., Saunders E.H., Brettin T.,
RA Bruce D., Han C., Tapia R., Gilna P., Schmutz J., Larimer F., Land M.,
RA Kyrpides N., Anderson I., Richardson P., Ragsdale S.;
RT "Complete sequence of Moorella thermoacetica ATCC 39073.";
RL Submitted (DEC-2005) to the EMBL/GenBank/DDBJ databases.
CC -!- COFACTOR:
CC Name=Zn(2+); Xref=ChEBI:CHEBI:29105;
CC Evidence={ECO:0000256|ARBA:ARBA00001947};
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DR EMBL; CP000232; ABC20394.1; -; Genomic_DNA.
DR RefSeq; YP_430937.1; NC_007644.1.
DR AlphaFoldDB; Q2RGP5; -.
DR STRING; 264732.Moth_2102; -.
DR EnsemblBacteria; ABC20394; ABC20394; Moth_2102.
DR KEGG; mta:Moth_2102; -.
DR PATRIC; fig|264732.11.peg.2285; -.
DR eggNOG; COG0407; Bacteria.
DR HOGENOM; CLU_040933_2_1_9; -.
DR OrthoDB; 8452307at2; -.
DR GO; GO:0008168; F:methyltransferase activity; IEA:UniProtKB-KW.
DR GO; GO:0004853; F:uroporphyrinogen decarboxylase activity; IEA:InterPro.
DR GO; GO:0015948; P:methanogenesis; IEA:UniProtKB-KW.
DR GO; GO:0032259; P:methylation; IEA:UniProtKB-KW.
DR GO; GO:0006730; P:one-carbon metabolic process; IEA:InterPro.
DR GO; GO:0006779; P:porphyrin-containing compound biosynthetic process; IEA:InterPro.
DR CDD; cd03307; Mta_CmuA_like; 1.
DR Gene3D; 3.20.20.210; -; 1.
DR InterPro; IPR006360; Mtase_MtaA_CmuA.
DR InterPro; IPR038071; UROD/MetE-like_sf.
DR InterPro; IPR000257; Uroporphyrinogen_deCOase.
DR NCBIfam; TIGR01463; mtaA_cmuA; 1.
DR PANTHER; PTHR47099; METHYLCOBAMIDE:COM METHYLTRANSFERASE MTBA; 1.
DR PANTHER; PTHR47099:SF1; METHYLCOBAMIDE:COM METHYLTRANSFERASE MTBA; 1.
DR Pfam; PF01208; URO-D; 1.
DR SUPFAM; SSF51726; UROD/MetE-like; 1.
PE 4: Predicted;
KW Methanogenesis {ECO:0000256|ARBA:ARBA00022994};
KW Methyltransferase {ECO:0000313|EMBL:ABC20394.1};
KW Transferase {ECO:0000313|EMBL:ABC20394.1}.
FT DOMAIN 5..334
FT /note="Uroporphyrinogen decarboxylase (URO-D)"
FT /evidence="ECO:0000259|Pfam:PF01208"
SQ SEQUENCE 338 AA; 37500 MW; BC7F7077029EDB77 CRC64;
MPAMTPKERF LRALNREHVD RIPVGNPVSV ATVESMEACG AYFPDVHLNP EKMATLAATG
YEILGFDTIA PYFSVQQEAA AFGLKMNWGT VDSMPDVLEN PFEDPDDIII PADFLERPPI
RTVLEALKIL KKEYGDHVCL VGKVMGPWTL SYHLHGVQKF LIKTILEPDK VRRFLDKLKD
LAVKFANAQF AAGADVVTVA DHATGDLVSG TCYRDFLLPI HQEMTRQLNG PTILHICGNT
TDRLDYIAQA GFNCFHFDSK VNPRQAHEIV NGRIALTGSI NNPKTLFNGT PDDVRREVFA
NCEAGIEIIS PECAVPLRTP NANLKAIVTA VEEYCRNH
//
