ID Q2RII2_MOOTA Unreviewed; 556 AA.
AC Q2RII2;
DT 24-JAN-2006, integrated into UniProtKB/TrEMBL.
DT 24-JAN-2006, sequence version 1.
DT 27-MAR-2024, entry version 90.
DE SubName: Full=Cobalamin B12-binding protein {ECO:0000313|EMBL:ABC19757.1};
GN OrderedLocusNames=Moth_1447 {ECO:0000313|EMBL:ABC19757.1};
OS Moorella thermoacetica (strain ATCC 39073 / JCM 9320).
OC Bacteria; Bacillota; Clostridia; Moorellales; Moorellaceae; Moorella.
OX NCBI_TaxID=264732 {ECO:0000313|EMBL:ABC19757.1};
RN [1] {ECO:0000313|EMBL:ABC19757.1}
RP NUCLEOTIDE SEQUENCE.
RC STRAIN=ATCC 39073 {ECO:0000313|EMBL:ABC19757.1};
RG US DOE Joint Genome Institute;
RA Copeland A., Lucas S., Lapidus A., Barry K., Detter J.C., Glavina T.,
RA Hammon N., Israni S., Pitluck S., Chertkov O., Saunders E.H., Brettin T.,
RA Bruce D., Han C., Tapia R., Gilna P., Schmutz J., Larimer F., Land M.,
RA Kyrpides N., Anderson I., Richardson P., Ragsdale S.;
RT "Complete sequence of Moorella thermoacetica ATCC 39073.";
RL Submitted (DEC-2005) to the EMBL/GenBank/DDBJ databases.
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DR EMBL; CP000232; ABC19757.1; -; Genomic_DNA.
DR RefSeq; YP_430300.1; NC_007644.1.
DR AlphaFoldDB; Q2RII2; -.
DR STRING; 264732.Moth_1447; -.
DR EnsemblBacteria; ABC19757; ABC19757; Moth_1447.
DR KEGG; mta:Moth_1447; -.
DR PATRIC; fig|264732.11.peg.1563; -.
DR eggNOG; COG0407; Bacteria.
DR eggNOG; COG5012; Bacteria.
DR HOGENOM; CLU_489854_0_0_9; -.
DR OrthoDB; 9780425at2; -.
DR GO; GO:0031419; F:cobalamin binding; IEA:InterPro.
DR GO; GO:0046872; F:metal ion binding; IEA:InterPro.
DR GO; GO:0004853; F:uroporphyrinogen decarboxylase activity; IEA:InterPro.
DR GO; GO:0006779; P:porphyrin-containing compound biosynthetic process; IEA:InterPro.
DR CDD; cd02070; corrinoid_protein_B12-BD; 1.
DR CDD; cd03465; URO-D_like; 1.
DR Gene3D; 3.20.20.210; -; 1.
DR Gene3D; 3.40.50.280; Cobalamin-binding domain; 1.
DR Gene3D; 1.10.1240.10; Methionine synthase domain; 1.
DR InterPro; IPR003759; Cbl-bd_cap.
DR InterPro; IPR006158; Cobalamin-bd.
DR InterPro; IPR036724; Cobalamin-bd_sf.
DR InterPro; IPR036594; Meth_synthase_dom.
DR InterPro; IPR038071; UROD/MetE-like_sf.
DR InterPro; IPR000257; Uroporphyrinogen_deCOase.
DR PANTHER; PTHR47099; METHYLCOBAMIDE:COM METHYLTRANSFERASE MTBA; 1.
DR PANTHER; PTHR47099:SF1; METHYLCOBAMIDE:COM METHYLTRANSFERASE MTBA; 1.
DR Pfam; PF02310; B12-binding; 1.
DR Pfam; PF02607; B12-binding_2; 1.
DR Pfam; PF01208; URO-D; 1.
DR SMART; SM01018; B12-binding_2; 1.
DR SUPFAM; SSF52242; Cobalamin (vitamin B12)-binding domain; 1.
DR SUPFAM; SSF47644; Methionine synthase domain; 1.
DR SUPFAM; SSF51726; UROD/MetE-like; 1.
DR PROSITE; PS51332; B12_BINDING; 1.
DR PROSITE; PS51337; B12_BINDING_NTER; 1.
PE 4: Predicted;
FT DOMAIN 325..419
FT /note="B12-binding N-terminal"
FT /evidence="ECO:0000259|PROSITE:PS51337"
FT DOMAIN 419..550
FT /note="B12-binding"
FT /evidence="ECO:0000259|PROSITE:PS51332"
SQ SEQUENCE 556 AA; 59805 MW; D79178899B37AAB0 CRC64;
MRLIDLVNQS GRHLVFFIGS FPGAAMKGVT LKEVYFSASL QAETACYLAE RFQIDFIRPV
TDLVVEAEAM GLKARYPDNG APVLVEHPIT GPEALANLNL PEPGRDGRLP INLEAIRLIK
QRTDKPVIGS LTGPFTLAGA LCDPAGVAMK TITDPEFLHA LLAFCTRALK RYGEALLAAG
ADILWISEPL GSLLSPAQFW QFSGRYIQEI FAAFPAMDIL HICGDTSYMI KEMLATGAQG
LSLDSRVSLP VLATQMPEDV VLIGNIDPVG VMLEGSPQQV VKATANLLTA MLPFNNFIVS
TGCTLPFEVP AANISAFVET ARNFPRLSPS QARLLLSLRR ALLEGDSEGV TTLTRKGLQL
EVDAITILEG GLIQGINRAG ELYQQQKVFI PELLLISQAM YAGLEVIRPV LVQKRHGTRG
EIVLGTVQGD LHDIGKNLVG LMLTANDYEV IDLGKDVAPE QFVEAVRACR PQVVGLSALT
TTTMKSMEKT VRALKQGGQG EQVKVIVGGA PITPEFARRI GADAYAPDAA AAVTEVANLI
DKVKEHQDGQ STTGVF
//
