ID Q2RIK5_MOOTA Unreviewed; 360 AA.
AC Q2RIK5;
DT 24-JAN-2006, integrated into UniProtKB/TrEMBL.
DT 24-JAN-2006, sequence version 1.
DT 27-MAR-2024, entry version 83.
DE SubName: Full=O-methyltransferase, family 2 {ECO:0000313|EMBL:ABC19734.1};
GN OrderedLocusNames=Moth_1421 {ECO:0000313|EMBL:ABC19734.1};
OS Moorella thermoacetica (strain ATCC 39073 / JCM 9320).
OC Bacteria; Bacillota; Clostridia; Moorellales; Moorellaceae; Moorella.
OX NCBI_TaxID=264732 {ECO:0000313|EMBL:ABC19734.1};
RN [1] {ECO:0000313|EMBL:ABC19734.1}
RP NUCLEOTIDE SEQUENCE.
RC STRAIN=ATCC 39073 {ECO:0000313|EMBL:ABC19734.1};
RG US DOE Joint Genome Institute;
RA Copeland A., Lucas S., Lapidus A., Barry K., Detter J.C., Glavina T.,
RA Hammon N., Israni S., Pitluck S., Chertkov O., Saunders E.H., Brettin T.,
RA Bruce D., Han C., Tapia R., Gilna P., Schmutz J., Larimer F., Land M.,
RA Kyrpides N., Anderson I., Richardson P., Ragsdale S.;
RT "Complete sequence of Moorella thermoacetica ATCC 39073.";
RL Submitted (DEC-2005) to the EMBL/GenBank/DDBJ databases.
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DR EMBL; CP000232; ABC19734.1; -; Genomic_DNA.
DR RefSeq; YP_430277.1; NC_007644.1.
DR AlphaFoldDB; Q2RIK5; -.
DR STRING; 264732.Moth_1421; -.
DR EnsemblBacteria; ABC19734; ABC19734; Moth_1421.
DR KEGG; mta:Moth_1421; -.
DR PATRIC; fig|264732.11.peg.1529; -.
DR eggNOG; COG4122; Bacteria.
DR HOGENOM; CLU_005533_4_3_9; -.
DR OrthoDB; 9816309at2; -.
DR GO; GO:0008171; F:O-methyltransferase activity; IEA:InterPro.
DR GO; GO:0032259; P:methylation; IEA:UniProtKB-KW.
DR CDD; cd02440; AdoMet_MTases; 1.
DR Gene3D; 3.40.50.150; Vaccinia Virus protein VP39; 1.
DR Gene3D; 1.10.10.10; Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain; 1.
DR InterPro; IPR031725; ASMT_dimerisation.
DR InterPro; IPR016461; COMT-like.
DR InterPro; IPR001077; O_MeTrfase_dom.
DR InterPro; IPR029063; SAM-dependent_MTases_sf.
DR InterPro; IPR036388; WH-like_DNA-bd_sf.
DR InterPro; IPR036390; WH_DNA-bd_sf.
DR PANTHER; PTHR11746:SF327; ACETYLSEROTONIN O-METHYLTRANSFERASE; 1.
DR PANTHER; PTHR11746; O-METHYLTRANSFERASE; 1.
DR Pfam; PF16864; Dimerisation2; 1.
DR Pfam; PF00891; Methyltransf_2; 1.
DR PIRSF; PIRSF005739; O-mtase; 2.
DR SUPFAM; SSF53335; S-adenosyl-L-methionine-dependent methyltransferases; 1.
DR SUPFAM; SSF46785; Winged helix' DNA-binding domain; 1.
DR PROSITE; PS51683; SAM_OMT_II; 1.
PE 4: Predicted;
KW Methyltransferase {ECO:0000313|EMBL:ABC19734.1};
KW S-adenosyl-L-methionine {ECO:0000256|ARBA:ARBA00022691};
KW Transferase {ECO:0000313|EMBL:ABC19734.1}.
FT DOMAIN 21..102
FT /note="Acetylserotonin O-methyltransferase dimerisation"
FT /evidence="ECO:0000259|Pfam:PF16864"
FT DOMAIN 146..273
FT /note="O-methyltransferase"
FT /evidence="ECO:0000259|Pfam:PF00891"
SQ SEQUENCE 360 AA; 39768 MW; FE526A4FCBAD6D30 CRC64;
MSNHPQSLMD LACPQGVERI DSITAGYQAY QVLRAALELG LFDWLAENGP GCREEITTAL
KLNGMFTRSF LQALVDLGFL TCKGEKYRLT ELARDFLVRR SPCYQGDLFL STARPDSWWN
NFKDTLTVIK PPEQDFDAVP TPDFIKALAQ RSLRGELQAV TRSIVAWEGF RGARTLLDLG
GGHGFYAIAL CQVNPNLRAV VFDKPHIIAC TREFIRQYGL EDRVIVQGGD ACSEEWGGGY
DIVLISHLLY KYRKELAAFI GKAFTALKPG GLLACNHWFC APGCGSEGDG LRELDRSIHS
FGHPLCHMEE FNNLLATTGF SLWQLLDVPS AYGMAKLHLA VKKGLASTKA MMPGSCSACC
//
