ID Q2RJ69_MOOTA Unreviewed; 224 AA.
AC Q2RJ69;
DT 24-JAN-2006, integrated into UniProtKB/TrEMBL.
DT 24-JAN-2006, sequence version 1.
DT 27-MAR-2024, entry version 88.
DE SubName: Full=Cobalamin B12-binding protein {ECO:0000313|EMBL:ABC19520.1};
GN OrderedLocusNames=Moth_1206 {ECO:0000313|EMBL:ABC19520.1};
OS Moorella thermoacetica (strain ATCC 39073 / JCM 9320).
OC Bacteria; Bacillota; Clostridia; Moorellales; Moorellaceae; Moorella.
OX NCBI_TaxID=264732 {ECO:0000313|EMBL:ABC19520.1};
RN [1] {ECO:0000313|EMBL:ABC19520.1}
RP NUCLEOTIDE SEQUENCE.
RC STRAIN=ATCC 39073 {ECO:0000313|EMBL:ABC19520.1};
RG US DOE Joint Genome Institute;
RA Copeland A., Lucas S., Lapidus A., Barry K., Detter J.C., Glavina T.,
RA Hammon N., Israni S., Pitluck S., Chertkov O., Saunders E.H., Brettin T.,
RA Bruce D., Han C., Tapia R., Gilna P., Schmutz J., Larimer F., Land M.,
RA Kyrpides N., Anderson I., Richardson P., Ragsdale S.;
RT "Complete sequence of Moorella thermoacetica ATCC 39073.";
RL Submitted (DEC-2005) to the EMBL/GenBank/DDBJ databases.
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR EMBL; CP000232; ABC19520.1; -; Genomic_DNA.
DR RefSeq; YP_430063.1; NC_007644.1.
DR AlphaFoldDB; Q2RJ69; -.
DR STRING; 264732.Moth_1206; -.
DR EnsemblBacteria; ABC19520; ABC19520; Moth_1206.
DR KEGG; mta:Moth_1206; -.
DR PATRIC; fig|264732.11.peg.1294; -.
DR eggNOG; COG5012; Bacteria.
DR HOGENOM; CLU_082102_2_0_9; -.
DR OrthoDB; 9803687at2; -.
DR GO; GO:0031419; F:cobalamin binding; IEA:InterPro.
DR GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR GO; GO:0008168; F:methyltransferase activity; IEA:UniProt.
DR CDD; cd02070; corrinoid_protein_B12-BD; 1.
DR Gene3D; 3.40.50.280; Cobalamin-binding domain; 1.
DR Gene3D; 1.10.1240.10; Methionine synthase domain; 1.
DR InterPro; IPR003759; Cbl-bd_cap.
DR InterPro; IPR006158; Cobalamin-bd.
DR InterPro; IPR036724; Cobalamin-bd_sf.
DR InterPro; IPR036594; Meth_synthase_dom.
DR PANTHER; PTHR45833; METHIONINE SYNTHASE; 1.
DR PANTHER; PTHR45833:SF1; METHIONINE SYNTHASE; 1.
DR Pfam; PF02310; B12-binding; 1.
DR Pfam; PF02607; B12-binding_2; 1.
DR SMART; SM01018; B12-binding_2; 1.
DR SUPFAM; SSF52242; Cobalamin (vitamin B12)-binding domain; 1.
DR SUPFAM; SSF47644; Methionine synthase domain; 1.
DR PROSITE; PS51332; B12_BINDING; 1.
DR PROSITE; PS51337; B12_BINDING_NTER; 1.
PE 4: Predicted;
KW Cobalt {ECO:0000256|ARBA:ARBA00023285};
KW Metal-binding {ECO:0000256|ARBA:ARBA00022723}.
FT DOMAIN 1..92
FT /note="B12-binding N-terminal"
FT /evidence="ECO:0000259|PROSITE:PS51337"
FT DOMAIN 91..222
FT /note="B12-binding"
FT /evidence="ECO:0000259|PROSITE:PS51332"
SQ SEQUENCE 224 AA; 24258 MW; A130FEB6EA857D9B CRC64;
MNGRTQIFQD IISAILRGEA NGVLKSINAG LQMGMSADEI LEEAMIPATI QTLDKYQGAD
FYIPDVINAS HAIEAGLFAL KPYTKKSLQK RKKIVIGTVE GDIHDIGKNL VALSLGYAGF
EVVDLGVNVS PAEFVRAVEQ HRPEILAMSA LLTTTMGEMA RVIKALEKHH LRKSVRVLVG
GGPVTKEFAE SIGADAYGSS AREAISIAQS LVRRCSDRER DYAC
//
