ID Q2RJH8_MOOTA Unreviewed; 210 AA.
AC Q2RJH8;
DT 24-JAN-2006, integrated into UniProtKB/TrEMBL.
DT 24-JAN-2006, sequence version 1.
DT 27-MAR-2024, entry version 81.
DE SubName: Full=Precorrin-8X methylmutase {ECO:0000313|EMBL:ABC19411.1};
DE EC=5.4.1.2 {ECO:0000313|EMBL:ABC19411.1};
GN OrderedLocusNames=Moth_1097 {ECO:0000313|EMBL:ABC19411.1};
OS Moorella thermoacetica (strain ATCC 39073 / JCM 9320).
OC Bacteria; Bacillota; Clostridia; Moorellales; Moorellaceae; Moorella.
OX NCBI_TaxID=264732 {ECO:0000313|EMBL:ABC19411.1};
RN [1] {ECO:0000313|EMBL:ABC19411.1}
RP NUCLEOTIDE SEQUENCE.
RC STRAIN=ATCC 39073 {ECO:0000313|EMBL:ABC19411.1};
RG US DOE Joint Genome Institute;
RA Copeland A., Lucas S., Lapidus A., Barry K., Detter J.C., Glavina T.,
RA Hammon N., Israni S., Pitluck S., Chertkov O., Saunders E.H., Brettin T.,
RA Bruce D., Han C., Tapia R., Gilna P., Schmutz J., Larimer F., Land M.,
RA Kyrpides N., Anderson I., Richardson P., Ragsdale S.;
RT "Complete sequence of Moorella thermoacetica ATCC 39073.";
RL Submitted (DEC-2005) to the EMBL/GenBank/DDBJ databases.
CC -!- PATHWAY: Cofactor biosynthesis; adenosylcobalamin biosynthesis.
CC {ECO:0000256|ARBA:ARBA00004953}.
CC -!- SIMILARITY: Belongs to the CobH/CbiC family.
CC {ECO:0000256|ARBA:ARBA00009774}.
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DR EMBL; CP000232; ABC19411.1; -; Genomic_DNA.
DR RefSeq; YP_429954.1; NC_007644.1.
DR AlphaFoldDB; Q2RJH8; -.
DR STRING; 264732.Moth_1097; -.
DR EnsemblBacteria; ABC19411; ABC19411; Moth_1097.
DR KEGG; mta:Moth_1097; -.
DR PATRIC; fig|264732.11.peg.1178; -.
DR eggNOG; COG2082; Bacteria.
DR HOGENOM; CLU_084703_1_1_9; -.
DR OrthoDB; 9780708at2; -.
DR UniPathway; UPA00148; -.
DR GO; GO:0016993; F:precorrin-8X methylmutase activity; IEA:InterPro.
DR GO; GO:0009236; P:cobalamin biosynthetic process; IEA:UniProtKB-UniPathway.
DR Gene3D; 3.40.50.10230; Cobalamin biosynthesis CobH/CbiC, precorrin-8X methylmutase; 1.
DR InterPro; IPR003722; Cbl_synth_CobH/CbiC.
DR InterPro; IPR036588; CobH/CbiC_sf.
DR PANTHER; PTHR43588; COBALT-PRECORRIN-8 METHYLMUTASE; 1.
DR PANTHER; PTHR43588:SF1; COBALT-PRECORRIN-8 METHYLMUTASE; 1.
DR Pfam; PF02570; CbiC; 1.
DR SUPFAM; SSF63965; Precorrin-8X methylmutase CbiC/CobH; 1.
PE 3: Inferred from homology;
KW Cobalamin biosynthesis {ECO:0000256|ARBA:ARBA00022573};
KW Isomerase {ECO:0000256|ARBA:ARBA00023235, ECO:0000313|EMBL:ABC19411.1}.
FT DOMAIN 10..203
FT /note="Cobalamin biosynthesis precorrin-8X methylmutase
FT CobH/CbiC"
FT /evidence="ECO:0000259|Pfam:PF02570"
SQ SEQUENCE 210 AA; 21466 MW; 2DDA6008635E1A6C CRC64;
MGFLSDPRAI EARSREIIAA RVGDLGLEPG ARAIVTRIIH ATGDLSYASL VAVHPGVVAA
ATAALRQGAD IITDVEMVRN GVSSHLVSRG GGRVLCAIRE AEVIKTATAR GETRAMVAME
YLAPRMDGAI VAIGNAPTAL FRLLELVAGG RAAPAAIVGT PVGFVGAAEA KAALETTGIP
YVTVRGPKGG STVAVAAVNA LLHLAWDEEE
//
