ID Q2S3C3_SALRD Unreviewed; 440 AA.
AC Q2S3C3;
DT 24-JAN-2006, integrated into UniProtKB/TrEMBL.
DT 24-JAN-2006, sequence version 1.
DT 27-MAR-2024, entry version 92.
DE SubName: Full=Membrane efflux protein {ECO:0000313|EMBL:ABC44622.1};
GN OrderedLocusNames=SRU_1183 {ECO:0000313|EMBL:ABC44622.1};
OS Salinibacter ruber (strain DSM 13855 / M31).
OC Bacteria; Rhodothermota; Rhodothermia; Rhodothermales; Salinibacteraceae;
OC Salinibacter.
OX NCBI_TaxID=309807 {ECO:0000313|EMBL:ABC44622.1, ECO:0000313|Proteomes:UP000008674};
RN [1] {ECO:0000313|EMBL:ABC44622.1, ECO:0000313|Proteomes:UP000008674}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=DSM 13855 / CECT 5946 / M31
RC {ECO:0000313|Proteomes:UP000008674};
RX PubMed=16330755; DOI=10.1073/pnas.0509073102;
RA Mongodin E.F., Nelson K.E., Daugherty S., Deboy R.T., Wister J., Khouri H.,
RA Weidman J., Walsh D.A., Papke R.T., Sanchez Perez G., Sharma A.K.,
RA Nesbo C.L., MacLeod D., Bapteste E., Doolittle W.F., Charlebois R.L.,
RA Legault B., Rodriguez-Valera F.;
RT "The genome of Salinibacter ruber: convergence and gene exchange among
RT hyperhalophilic bacteria and archaea.";
RL Proc. Natl. Acad. Sci. U.S.A. 102:18147-18152(2005).
CC -!- SIMILARITY: Belongs to the membrane fusion protein (MFP) (TC 8.A.1)
CC family. {ECO:0000256|ARBA:ARBA00009477}.
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DR EMBL; CP000159; ABC44622.1; -; Genomic_DNA.
DR RefSeq; YP_445308.1; NC_007677.1.
DR AlphaFoldDB; Q2S3C3; -.
DR STRING; 309807.SRU_1183; -.
DR EnsemblBacteria; ABC44622; ABC44622; SRU_1183.
DR KEGG; sru:SRU_1183; -.
DR eggNOG; COG0845; Bacteria.
DR HOGENOM; CLU_603938_0_0_10; -.
DR OrthoDB; 9806939at2; -.
DR Proteomes; UP000008674; Chromosome.
DR GO; GO:0016020; C:membrane; IEA:InterPro.
DR GO; GO:0022857; F:transmembrane transporter activity; IEA:InterPro.
DR Gene3D; 2.40.30.170; -; 1.
DR Gene3D; 2.40.420.20; -; 1.
DR Gene3D; 2.40.50.100; -; 1.
DR Gene3D; 1.10.287.470; Helix hairpin bin; 1.
DR InterPro; IPR032317; HlyD_D23.
DR InterPro; IPR006143; RND_pump_MFP.
DR NCBIfam; TIGR01730; RND_mfp; 1.
DR PANTHER; PTHR30469:SF15; HLYD FAMILY OF SECRETION PROTEINS; 1.
DR PANTHER; PTHR30469; MULTIDRUG RESISTANCE PROTEIN MDTA; 1.
DR Pfam; PF16576; HlyD_D23; 1.
DR SUPFAM; SSF111369; HlyD-like secretion proteins; 1.
PE 3: Inferred from homology;
KW Coiled coil {ECO:0000256|SAM:Coils};
KW Reference proteome {ECO:0000313|Proteomes:UP000008674}.
FT DOMAIN 50..279
FT /note="RND efflux pump membrane fusion protein barrel-
FT sandwich"
FT /evidence="ECO:0000259|Pfam:PF16576"
FT REGION 1..45
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 419..440
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COILED 85..171
FT /evidence="ECO:0000256|SAM:Coils"
FT COMPBIAS 1..29
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 422..440
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 440 AA; 47924 MW; 7CCB4438F983BB15 CRC64;
MLSGCGSSSG EGDASRRGQG NSSPPSVEAV QARDGTLPLE ERMSGTVRAR NQTAIYSELS
QPVVAVEAQT GDYVEKGEPL VRLRRVTYEQ QVRQAEAALR TAKAEAQGAQ ANLRGLRSQL
KRTERLADQD FESQQQLESL RAQVEQAEAT YEQAQAQVEQ AESTLQERET TLRRTVVRAP
ISGHVGQRNV QVGQRVGPDT RLYTIGDLDS VKVNVEVTDR MFGRIRPGQT ARIHVPQQDT
VLVAPVARMS PFLSEESYSA EAVIEVSNDP RLLNPGMFVE VDVAYGESER ATIVPLSALY
ENPGSNARGV FVAPTLGTEI PVDVPEDFNA DNPPPLTPPT PTTFRKVEVV AEGQQTAGIR
GVEPGDWVVT VGKNQISAAG QGRVDARVRP MSWSRLMALQ RLQDTDLLYD VLERQQRIAE
QRFGGEDSTS SDSAQSSTGS
//
