ID   Q2S597_SALRD            Unreviewed;       596 AA.
AC   Q2S597;
DT   24-JAN-2006, integrated into UniProtKB/TrEMBL.
DT   24-JAN-2006, sequence version 1.
DT   27-MAR-2024, entry version 100.
DE   SubName: Full=Ribonuclease, Rne/Rng family subfamily {ECO:0000313|EMBL:ABC44436.1};
GN   OrderedLocusNames=SRU_0489 {ECO:0000313|EMBL:ABC44436.1};
OS   Salinibacter ruber (strain DSM 13855 / M31).
OC   Bacteria; Rhodothermota; Rhodothermia; Rhodothermales; Salinibacteraceae;
OC   Salinibacter.
OX   NCBI_TaxID=309807 {ECO:0000313|EMBL:ABC44436.1, ECO:0000313|Proteomes:UP000008674};
RN   [1] {ECO:0000313|EMBL:ABC44436.1, ECO:0000313|Proteomes:UP000008674}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=DSM 13855 / CECT 5946 / M31
RC   {ECO:0000313|Proteomes:UP000008674};
RX   PubMed=16330755; DOI=10.1073/pnas.0509073102;
RA   Mongodin E.F., Nelson K.E., Daugherty S., Deboy R.T., Wister J., Khouri H.,
RA   Weidman J., Walsh D.A., Papke R.T., Sanchez Perez G., Sharma A.K.,
RA   Nesbo C.L., MacLeod D., Bapteste E., Doolittle W.F., Charlebois R.L.,
RA   Legault B., Rodriguez-Valera F.;
RT   "The genome of Salinibacter ruber: convergence and gene exchange among
RT   hyperhalophilic bacteria and archaea.";
RL   Proc. Natl. Acad. Sci. U.S.A. 102:18147-18152(2005).
CC   -!- COFACTOR:
CC       Name=Mg(2+); Xref=ChEBI:CHEBI:18420;
CC         Evidence={ECO:0000256|ARBA:ARBA00001946};
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DR   EMBL; CP000159; ABC44436.1; -; Genomic_DNA.
DR   RefSeq; WP_011403267.1; NC_007677.1.
DR   RefSeq; YP_444634.1; NC_007677.1.
DR   AlphaFoldDB; Q2S597; -.
DR   SMR; Q2S597; -.
DR   STRING; 309807.SRU_0489; -.
DR   EnsemblBacteria; ABC44436; ABC44436; SRU_0489.
DR   KEGG; sru:SRU_0489; -.
DR   PATRIC; fig|309807.25.peg.512; -.
DR   eggNOG; COG1530; Bacteria.
DR   HOGENOM; CLU_003468_5_3_10; -.
DR   OrthoDB; 9804278at2; -.
DR   Proteomes; UP000008674; Chromosome.
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0003723; F:RNA binding; IEA:UniProtKB-KW.
DR   GO; GO:0004540; F:RNA nuclease activity; IEA:InterPro.
DR   GO; GO:0006396; P:RNA processing; IEA:InterPro.
DR   CDD; cd04453; S1_RNase_E; 1.
DR   Gene3D; 2.40.50.140; Nucleic acid-binding proteins; 1.
DR   InterPro; IPR012340; NA-bd_OB-fold.
DR   InterPro; IPR019307; RNA-bd_AU-1/RNase_E/G.
DR   InterPro; IPR004659; RNase_E/G.
DR   InterPro; IPR003029; S1_domain.
DR   NCBIfam; TIGR00757; RNaseEG; 1.
DR   PANTHER; PTHR30001; RIBONUCLEASE; 1.
DR   PANTHER; PTHR30001:SF0; RIBONUCLEASE G; 1.
DR   Pfam; PF10150; RNase_E_G; 1.
DR   SMART; SM00316; S1; 1.
DR   SUPFAM; SSF50249; Nucleic acid-binding proteins; 1.
DR   PROSITE; PS50126; S1; 1.
PE   4: Predicted;
KW   Hydrolase {ECO:0000256|ARBA:ARBA00022801};
KW   Magnesium {ECO:0000256|ARBA:ARBA00022842};
KW   Metal-binding {ECO:0000256|ARBA:ARBA00022723};
KW   Reference proteome {ECO:0000313|Proteomes:UP000008674};
KW   RNA-binding {ECO:0000256|ARBA:ARBA00022884}.
FT   DOMAIN          39..142
FT                   /note="S1 motif"
FT                   /evidence="ECO:0000259|PROSITE:PS50126"
FT   REGION          412..517
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        434..484
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        491..509
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   596 AA;  66918 MW;  2300B86E1C9C935D CRC64;
     MSKEIVFNVG NEQTRIAIVE DGKLVELYIE NAEHKRTIGN LYLGQIRKVM PSIQAAFVDI
     GQEQDAFLHF SDLSDNLPYL LDFLGLEAPT VEAIDVPKGK KDWDKRPSDL LNRGQTILVQ
     VTKEPISNKG SRISTDISLA GRFLVLVPLQ NYVAVSRKIT DDEERRRLES LASSLVPDGV
     GVIVRTVAQD RDAKSLDKDM KLLMERWRRV EKRLKDKPSP PELVHEDVDM ASSIVRDEFS
     EEYDRILVDH EGLYSSIQSY VRAVGPQLVD RVELHEGDQP VFESVGIQHG ADRAFKDRVE
     LPSGGYLFIE KTEAMHVVDV NSGRSGKGKS QAENSLNVNL EAARVIARQI RLRDLGGIIV
     VDFIDLRDED DKKKVYDEVK KGFEEDRAVT KVLPMSDFGL VEITRQRLRP SITTTFSSAN
     GTPSDDGDDG ADPEELRQAE RKIQSLEKEV EKREREVKRL KAEDDTPDEE VTALRQKIQA
     LEDKLEAARA QQTAENATPR PSSSDGSAAS AEGDAAPDEL VEDIEQWLVA HSDTHRAVTL
     RVHPFVAAFL RRPVPTYTTR WFMEHLVRVH VEADTEVPPH TFQVTDESGA PLPESP
//