ID Q2TY14_ASPOR Unreviewed; 812 AA.
AC Q2TY14;
DT 24-JAN-2006, integrated into UniProtKB/TrEMBL.
DT 24-JAN-2006, sequence version 1.
DT 27-MAR-2024, entry version 78.
DE SubName: Full=Uncharacterized protein {ECO:0000313|EMBL:BAE65859.1};
GN ORFNames=AO090103000430 {ECO:0000313|EMBL:BAE65859.1};
OS Aspergillus oryzae (strain ATCC 42149 / RIB 40) (Yellow koji mold).
OC Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Eurotiomycetes;
OC Eurotiomycetidae; Eurotiales; Aspergillaceae; Aspergillus;
OC Aspergillus subgen. Circumdati.
OX NCBI_TaxID=510516 {ECO:0000313|EMBL:BAE65859.1, ECO:0000313|Proteomes:UP000006564};
RN [1] {ECO:0000313|EMBL:BAE65859.1, ECO:0000313|Proteomes:UP000006564}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC 42149 / RIB 40 {ECO:0000313|Proteomes:UP000006564};
RX PubMed=16372010; DOI=10.1038/nature04300;
RA Machida M., Asai K., Sano M., Tanaka T., Kumagai T., Terai G., Kusumoto K.,
RA Arima T., Akita O., Kashiwagi Y., Abe K., Gomi K., Horiuchi H.,
RA Kitamoto K., Kobayashi T., Takeuchi M., Denning D.W., Galagan J.E.,
RA Nierman W.C., Yu J., Archer D.B., Bennett J.W., Bhatnagar D.,
RA Cleveland T.E., Fedorova N.D., Gotoh O., Horikawa H., Hosoyama A.,
RA Ichinomiya M., Igarashi R., Iwashita K., Juvvadi P.R., Kato M., Kato Y.,
RA Kin T., Kokubun A., Maeda H., Maeyama N., Maruyama J., Nagasaki H.,
RA Nakajima T., Oda K., Okada K., Paulsen I., Sakamoto K., Sawano T.,
RA Takahashi M., Takase K., Terabayashi Y., Wortman J., Yamada O.,
RA Yamagata Y., Anazawa H., Hata Y., Koide Y., Komori T., Koyama Y.,
RA Minetoki T., Suharnan S., Tanaka A., Isono K., Kuhara S., Ogasawara N.,
RA Kikuchi H.;
RT "Genome sequencing and analysis of Aspergillus oryzae.";
RL Nature 438:1157-1161(2005).
CC -!- SIMILARITY: In the 2nd section; belongs to the type-I 3-dehydroquinase
CC family. {ECO:0000256|ARBA:ARBA00006477}.
CC -!- SIMILARITY: In the N-terminal section; belongs to the shikimate kinase
CC family. {ECO:0000256|ARBA:ARBA00009349}.
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DR EMBL; AP007174; BAE65859.1; -; Genomic_DNA.
DR AlphaFoldDB; Q2TY14; -.
DR STRING; 510516.Q2TY14; -.
DR EnsemblFungi; BAE65859; BAE65859; AO090103000430.
DR VEuPathDB; FungiDB:AO090103000430; -.
DR HOGENOM; CLU_008871_0_1_1; -.
DR OMA; AQYELFT; -.
DR OrthoDB; 2256238at2759; -.
DR Proteomes; UP000006564; Chromosome 8.
DR GO; GO:0003855; F:3-dehydroquinate dehydratase activity; IEA:InterPro.
DR GO; GO:0004764; F:shikimate 3-dehydrogenase (NADP+) activity; IEA:InterPro.
DR CDD; cd01065; NAD_bind_Shikimate_DH; 1.
DR Gene3D; 3.20.20.70; Aldolase class I; 1.
DR Gene3D; 3.40.50.10860; Leucine Dehydrogenase, chain A, domain 1; 1.
DR Gene3D; 3.40.50.720; NAD(P)-binding Rossmann-like Domain; 1.
DR Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 1.
DR InterPro; IPR013785; Aldolase_TIM.
DR InterPro; IPR046346; Aminoacid_DH-like_N_sf.
DR InterPro; IPR001381; DHquinase_I.
DR InterPro; IPR036291; NAD(P)-bd_dom_sf.
DR InterPro; IPR027417; P-loop_NTPase.
DR InterPro; IPR041121; SDH_C.
DR InterPro; IPR031322; Shikimate/glucono_kinase.
DR InterPro; IPR013708; Shikimate_DH-bd_N.
DR InterPro; IPR022893; Shikimate_DH_fam.
DR InterPro; IPR006151; Shikm_DH/Glu-tRNA_Rdtase.
DR PANTHER; PTHR21089:SF1; BIFUNCTIONAL 3-DEHYDROQUINATE DEHYDRATASE_SHIKIMATE DEHYDROGENASE, CHLOROPLASTIC; 1.
DR PANTHER; PTHR21089; SHIKIMATE DEHYDROGENASE; 1.
DR Pfam; PF01487; DHquinase_I; 1.
DR Pfam; PF18317; SDH_C; 1.
DR Pfam; PF01488; Shikimate_DH; 1.
DR Pfam; PF08501; Shikimate_dh_N; 1.
DR Pfam; PF01202; SKI; 1.
DR SUPFAM; SSF53223; Aminoacid dehydrogenase-like, N-terminal domain; 1.
DR SUPFAM; SSF51735; NAD(P)-binding Rossmann-fold domains; 1.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
PE 3: Inferred from homology;
KW Reference proteome {ECO:0000313|Proteomes:UP000006564}.
FT DOMAIN 512..592
FT /note="Shikimate dehydrogenase substrate binding N-
FT terminal"
FT /evidence="ECO:0000259|Pfam:PF08501"
FT DOMAIN 635..681
FT /note="Quinate/shikimate 5-dehydrogenase/glutamyl-tRNA
FT reductase"
FT /evidence="ECO:0000259|Pfam:PF01488"
FT DOMAIN 774..804
FT /note="SDH C-terminal"
FT /evidence="ECO:0000259|Pfam:PF18317"
SQ SEQUENCE 812 AA; 90765 MW; 30AE9F9B639A71C0 CRC64;
MDSISVFETF TGVWVVRSGL CVSHDSHWWS SSPSPRASYI SSCETGANRR LTPLATLELR
HIDVFQVPSS HVQHHGLPSS SRRYSSDASL VLVGFPGAGK KTLGIMAAVA LRRRLVDFVA
VFQQRHGMHP QAYIVSHGSE RYRKLELEVT EEILTEHRKG CVIVGLGWLA SRQQQVLLEE
FASCHPVLYI RRDRRDLQQL IATSQDKFER MWDAGNSFFE SCSNLEFYNV TEGSTDEARS
ALPAYLKLKE TERTFVRFLH RIWGREHLTR YSADPLSASY TYALQVPMAC LEGPLESYEE
LENGADAINL KVELSEFHGR RPSESMARAV AMLRRHSRAL VIVDIIPSSV PDILSYRKLL
GMALRTIPDA ITCSMAHGDD LAQEVAAAKG YIKAIATYHQ EYSLARNETR PELFTFRQKA
QSIGFDAIHI TGESTAPGDS LHGISFPHTL AKDSLIPTIA YDTGLFGRTS VCLNPILSPV
VLESMKPTGV TLREAEMAVS ACFLRRRKRF GIFGQQLSHT LSPAMHNAAY AACGLPYTYG
IAERERLSDI REILDDESYG GVAVSLPYKT EVLPYLDEIS PEALDINAVN TVVLHQECQP
NGVRKTIRKG YNTDYLGIKD CIYKHLSPAN AIRDGSTALI IGAGGMAHAA IYACYQLGVR
RICVYNRTLS NARRLVDYYR EWVKSKDKAP LELTILSSAD DPWPAHLRQP TVIVSCIPGQ
KCDIESSSAL NIPDHWLQSR TGGVFVEVAY DPLETRLIRS MRQHVSRGWI IVDGLSVLVE
QGIAQYELFT TRPAPVHVMR RAIQQSILER TV
//
