ID Q2TYP4_ASPOR Unreviewed; 1327 AA.
AC Q2TYP4;
DT 24-JAN-2006, integrated into UniProtKB/TrEMBL.
DT 24-JAN-2006, sequence version 1.
DT 27-MAR-2024, entry version 116.
DE RecName: Full=ABC transporter transmembrane region {ECO:0008006|Google:ProtNLM};
GN ORFNames=AO090103000166 {ECO:0000313|EMBL:BAE65629.1};
OS Aspergillus oryzae (strain ATCC 42149 / RIB 40) (Yellow koji mold).
OC Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Eurotiomycetes;
OC Eurotiomycetidae; Eurotiales; Aspergillaceae; Aspergillus;
OC Aspergillus subgen. Circumdati.
OX NCBI_TaxID=510516 {ECO:0000313|EMBL:BAE65629.1, ECO:0000313|Proteomes:UP000006564};
RN [1] {ECO:0000313|EMBL:BAE65629.1, ECO:0000313|Proteomes:UP000006564}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC 42149 / RIB 40 {ECO:0000313|Proteomes:UP000006564};
RX PubMed=16372010; DOI=10.1038/nature04300;
RA Machida M., Asai K., Sano M., Tanaka T., Kumagai T., Terai G., Kusumoto K.,
RA Arima T., Akita O., Kashiwagi Y., Abe K., Gomi K., Horiuchi H.,
RA Kitamoto K., Kobayashi T., Takeuchi M., Denning D.W., Galagan J.E.,
RA Nierman W.C., Yu J., Archer D.B., Bennett J.W., Bhatnagar D.,
RA Cleveland T.E., Fedorova N.D., Gotoh O., Horikawa H., Hosoyama A.,
RA Ichinomiya M., Igarashi R., Iwashita K., Juvvadi P.R., Kato M., Kato Y.,
RA Kin T., Kokubun A., Maeda H., Maeyama N., Maruyama J., Nagasaki H.,
RA Nakajima T., Oda K., Okada K., Paulsen I., Sakamoto K., Sawano T.,
RA Takahashi M., Takase K., Terabayashi Y., Wortman J., Yamada O.,
RA Yamagata Y., Anazawa H., Hata Y., Koide Y., Komori T., Koyama Y.,
RA Minetoki T., Suharnan S., Tanaka A., Isono K., Kuhara S., Ogasawara N.,
RA Kikuchi H.;
RT "Genome sequencing and analysis of Aspergillus oryzae.";
RL Nature 438:1157-1161(2005).
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-
CC pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
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DR EMBL; AP007174; BAE65629.1; -; Genomic_DNA.
DR RefSeq; XP_001826762.1; XM_001826710.2.
DR STRING; 510516.Q2TYP4; -.
DR EnsemblFungi; BAE65629; BAE65629; AO090103000166.
DR GeneID; 5998884; -.
DR KEGG; aor:AO090103000166; -.
DR VEuPathDB; FungiDB:AO090103000166; -.
DR HOGENOM; CLU_000604_17_0_1; -.
DR OMA; RANVMHQ; -.
DR OrthoDB; 1067095at2759; -.
DR Proteomes; UP000006564; Chromosome 8.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0140359; F:ABC-type transporter activity; IEA:InterPro.
DR GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR GO; GO:0016887; F:ATP hydrolysis activity; IEA:InterPro.
DR CDD; cd18577; ABC_6TM_Pgp_ABCB1_D1_like; 1.
DR CDD; cd18578; ABC_6TM_Pgp_ABCB1_D2_like; 1.
DR Gene3D; 1.20.1560.10; ABC transporter type 1, transmembrane domain; 1.
DR Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 2.
DR InterPro; IPR003593; AAA+_ATPase.
DR InterPro; IPR011527; ABC1_TM_dom.
DR InterPro; IPR036640; ABC1_TM_sf.
DR InterPro; IPR003439; ABC_transporter-like_ATP-bd.
DR InterPro; IPR017871; ABC_transporter-like_CS.
DR InterPro; IPR027417; P-loop_NTPase.
DR InterPro; IPR039421; Type_1_exporter.
DR PANTHER; PTHR24221:SF219; ABC MULTIDRUG TRANSPORTER (EUROFUNG); 1.
DR PANTHER; PTHR24221; ATP-BINDING CASSETTE SUB-FAMILY B; 1.
DR Pfam; PF00664; ABC_membrane; 2.
DR Pfam; PF00005; ABC_tran; 2.
DR SMART; SM00382; AAA; 2.
DR SUPFAM; SSF90123; ABC transporter transmembrane region; 2.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 2.
DR PROSITE; PS50929; ABC_TM1F; 2.
DR PROSITE; PS00211; ABC_TRANSPORTER_1; 2.
DR PROSITE; PS50893; ABC_TRANSPORTER_2; 2.
PE 4: Predicted;
KW ATP-binding {ECO:0000256|ARBA:ARBA00022840};
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741};
KW Reference proteome {ECO:0000313|Proteomes:UP000006564};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}.
FT TRANSMEM 27..48
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 80..103
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 155..174
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 180..201
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 294..316
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 734..760
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 780..806
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 850..875
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 881..902
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 964..986
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 998..1021
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 28..328
FT /note="ABC transmembrane type-1"
FT /evidence="ECO:0000259|PROSITE:PS50929"
FT DOMAIN 363..642
FT /note="ABC transporter"
FT /evidence="ECO:0000259|PROSITE:PS50893"
FT DOMAIN 738..1026
FT /note="ABC transmembrane type-1"
FT /evidence="ECO:0000259|PROSITE:PS50929"
FT DOMAIN 1083..1322
FT /note="ABC transporter"
FT /evidence="ECO:0000259|PROSITE:PS50893"
FT REGION 648..715
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1046..1070
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 660..675
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 1327 AA; 143269 MW; FE7B4744F4D514BF CRC64;
MKLGKKLAGY PSLLLAGNPS KVDIGRLLLG MVASAASGVP FPLIAILFGQ LLDDFNAVTC
DETESTGSDA DYQHDINGKI LIIVYLAIAQ FVAIYIHLSC WSLNGARLAQ RLRETYLQNL
LRQEPSFFDD LPPGELASRL NGDIQAIRSG TSEKVGICLS TLSFFITAYV VAFIKDYRLA
AMLISLVPAY FLMSFVGSHY IEKYSGRMSD YSATAASIAS EALSNTVVVQ AFGASYRLED
KFSKALKASE QEGLKKAAAV GIQSGFLYFI AYSANGLAFW QGSRRVADAV GSDTAGATVG
ATFTVIFVLV EATLLLSQVA PFLHLFTAAV ASYQKLRADI DRQPQIDATT ESGIRLSQAE
GGFEFKNVSF TYPSRPEITV LDQISLSIPA NKHTALVGLS GSGKSTIAGL VTRLYDPTEG
QVLFDGHDLR EVNTRDLRSF LSLVQQEPSL LDRSLLENIA HGLINSSNPS HAHLRTTLLS
TGLTDLAAEV REGVDLMAAA EKRGSEVVEI VNLVRKAATL ADADGFISAL QYGYGTLVGS
SGRLISGGQK QRVSLARALI KDPAVLILDE ATASLDSRSE QRIQRAISNI ATGRTMITIA
HRLSTITNAD NIIVMHKGHI VEQGDHATLM AKNGAYADLV NLQTLGSAPG KKEKTASADN
VSKSDQASLS DAGVEESSVS KDGLETAEKK EVLASAAPVT EPAEPAEEEE EPETPKKSMW
ALLRGYAPTL RPHLLFIFLA LLGSSIVGGA FSGEAVIFGN TVGSLNPCHS ESYIRSAGNF
FGLMFFVLAI IEFFANLVSW TGFGWVSEKI VFTVRVLSFR SLFEQDLQWH QSNGRSPALL
LSYITRDGNA LAGLSGSVIG TLFSITVNLI AAIILTHIIA WRIALVCLAL VPLLLGAGLM
ELHVLGKFEE RHENAYTKSV DIGVEAVTSI KTIASLSLEE DTLRTYRRSL KGPRKETFQV
TLHASLWQAM TYFLGNCVNA LAYWWGSKQI INGNYTQTQF LIVVFSLLVS ALLWSQMFAL
APELSAARAA MARILGLIEI GSDKMQGRVP SRSPTISSSE EKDVETAETK SVYVSGNNRA
SSVQLRNIHF AYPARPDIKV LKGLDVDIHP GQFCALVGPS GAGKSTIISL VERLYTPETG
SIVIDGVDVT RHRGVDFRDS IALVPQESVL FEGSIEFNIG LGARPGHEAT IEEIKEACKL
ANIHDVIEAL PEGYKTLCGP NGSQFSGGQK QRLSIARALV RKPKLLILDE STSALDAESE
KLLQDGLEKA AKGITVIAIA HRLHTIRAAD VIFLIEGGKC IDRGSHEELL ERSDSYRANV
MHQTVAT
//
