ID Q2U9X4_ASPOR Unreviewed; 474 AA.
AC Q2U9X4;
DT 24-JAN-2006, integrated into UniProtKB/TrEMBL.
DT 24-JAN-2006, sequence version 1.
DT 27-MAR-2024, entry version 88.
DE RecName: Full=Citrate synthase {ECO:0000256|RuleBase:RU000441};
GN ORFNames=AO090102000627 {ECO:0000313|EMBL:BAE61641.1};
OS Aspergillus oryzae (strain ATCC 42149 / RIB 40) (Yellow koji mold).
OC Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Eurotiomycetes;
OC Eurotiomycetidae; Eurotiales; Aspergillaceae; Aspergillus;
OC Aspergillus subgen. Circumdati.
OX NCBI_TaxID=510516 {ECO:0000313|EMBL:BAE61641.1, ECO:0000313|Proteomes:UP000006564};
RN [1] {ECO:0000313|EMBL:BAE61641.1, ECO:0000313|Proteomes:UP000006564}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC 42149 / RIB 40 {ECO:0000313|Proteomes:UP000006564};
RX PubMed=16372010; DOI=10.1038/nature04300;
RA Machida M., Asai K., Sano M., Tanaka T., Kumagai T., Terai G., Kusumoto K.,
RA Arima T., Akita O., Kashiwagi Y., Abe K., Gomi K., Horiuchi H.,
RA Kitamoto K., Kobayashi T., Takeuchi M., Denning D.W., Galagan J.E.,
RA Nierman W.C., Yu J., Archer D.B., Bennett J.W., Bhatnagar D.,
RA Cleveland T.E., Fedorova N.D., Gotoh O., Horikawa H., Hosoyama A.,
RA Ichinomiya M., Igarashi R., Iwashita K., Juvvadi P.R., Kato M., Kato Y.,
RA Kin T., Kokubun A., Maeda H., Maeyama N., Maruyama J., Nagasaki H.,
RA Nakajima T., Oda K., Okada K., Paulsen I., Sakamoto K., Sawano T.,
RA Takahashi M., Takase K., Terabayashi Y., Wortman J., Yamada O.,
RA Yamagata Y., Anazawa H., Hata Y., Koide Y., Komori T., Koyama Y.,
RA Minetoki T., Suharnan S., Tanaka A., Isono K., Kuhara S., Ogasawara N.,
RA Kikuchi H.;
RT "Genome sequencing and analysis of Aspergillus oryzae.";
RL Nature 438:1157-1161(2005).
CC -!- SIMILARITY: Belongs to the citrate synthase family.
CC {ECO:0000256|ARBA:ARBA00010566, ECO:0000256|RuleBase:RU000441}.
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DR EMBL; AP007162; BAE61641.1; -; Genomic_DNA.
DR RefSeq; XP_001822774.1; XM_001822722.2.
DR AlphaFoldDB; Q2U9X4; -.
DR SMR; Q2U9X4; -.
DR STRING; 510516.Q2U9X4; -.
DR EnsemblFungi; BAE61641; BAE61641; AO090102000627.
DR GeneID; 5994819; -.
DR KEGG; aor:AO090102000627; -.
DR VEuPathDB; FungiDB:AO090102000627; -.
DR HOGENOM; CLU_022049_2_1_1; -.
DR OMA; VLEWLFK; -.
DR OrthoDB; 3513214at2759; -.
DR Proteomes; UP000006564; Chromosome 4.
DR GO; GO:0005739; C:mitochondrion; IDA:AspGD.
DR GO; GO:0004108; F:citrate (Si)-synthase activity; IEA:EnsemblFungi.
DR GO; GO:0006101; P:citrate metabolic process; IEA:EnsemblFungi.
DR GO; GO:0006099; P:tricarboxylic acid cycle; IEA:EnsemblFungi.
DR CDD; cd06105; ScCit1-2_like; 1.
DR Gene3D; 1.10.580.10; Citrate Synthase, domain 1; 1.
DR Gene3D; 1.10.230.10; Cytochrome P450-Terp, domain 2; 1.
DR InterPro; IPR016142; Citrate_synth-like_lrg_a-sub.
DR InterPro; IPR016143; Citrate_synth-like_sm_a-sub.
DR InterPro; IPR002020; Citrate_synthase.
DR InterPro; IPR019810; Citrate_synthase_AS.
DR InterPro; IPR010109; Citrate_synthase_euk.
DR InterPro; IPR036969; Citrate_synthase_sf.
DR NCBIfam; TIGR01793; cit_synth_euk; 1.
DR PANTHER; PTHR11739; CITRATE SYNTHASE; 1.
DR PANTHER; PTHR11739:SF8; CITRATE SYNTHASE, MITOCHONDRIAL; 1.
DR Pfam; PF00285; Citrate_synt; 1.
DR PRINTS; PR00143; CITRTSNTHASE.
DR SUPFAM; SSF48256; Citrate synthase; 1.
DR PROSITE; PS00480; CITRATE_SYNTHASE; 1.
PE 3: Inferred from homology;
KW Reference proteome {ECO:0000313|Proteomes:UP000006564};
KW Transferase {ECO:0000256|ARBA:ARBA00022679, ECO:0000256|RuleBase:RU000441}.
FT ACT_SITE 310
FT /evidence="ECO:0000256|PIRSR:PIRSR610109-1"
FT ACT_SITE 356
FT /evidence="ECO:0000256|PIRSR:PIRSR610109-1"
FT ACT_SITE 411
FT /evidence="ECO:0000256|PIRSR:PIRSR610109-1"
SQ SEQUENCE 474 AA; 52028 MW; 2A36EB2CB8314A8F CRC64;
MASSLRIGTS VLRSTSLAGK PVVQSVAFNG LRCYSTGKAK SLKETFADNL PGEIEKVKKL
RKDYGNKVIG EVTLDQAYGG ARGVKCLVWE GSVLDSEEGI RFRGYTIPEC QKLLPKAPGG
EEPLPEGLFW LLLTGEIPSE QQVRDLSAEW AARSDLPKFI EELIDRCPST LHPMAQFSLA
VTALEHESAF AKAYAKGINK KDYWNYTFED SMDLIAKLPT IAAKIYRNVF KDGKVAPIQK
DKDYSYNLAN QLGFGNNNDF VELMRLYLTI HSDHEGGNVS AHTTHLVGSA LSSPMLSLSA
GLNGLAGPLH GLANQEVLNW LTKMKAAIGN DLSDQAIKDY LWSTLNAGQV VPGYGHAVLR
KTDPRYVSQR EFALRKLPDD QMFNLVSQVY KIAPGVLTEH GKTKNPFPNV DAHSGVLLQY
YGLTEANYYT VLFGVSRALG VLPQLIIDRA LGAPIERPKS FSTEAYAKLV GAKL
//
