ID Q2UER4_ASPOR Unreviewed; 623 AA.
AC Q2UER4;
DT 24-JAN-2006, integrated into UniProtKB/TrEMBL.
DT 24-JAN-2006, sequence version 1.
DT 27-MAR-2024, entry version 79.
DE RecName: Full=AMP-dependent synthetase/ligase domain-containing protein {ECO:0000259|Pfam:PF00501};
GN ORFNames=AO090026000514 {ECO:0000313|EMBL:BAE59951.1};
OS Aspergillus oryzae (strain ATCC 42149 / RIB 40) (Yellow koji mold).
OC Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Eurotiomycetes;
OC Eurotiomycetidae; Eurotiales; Aspergillaceae; Aspergillus;
OC Aspergillus subgen. Circumdati.
OX NCBI_TaxID=510516 {ECO:0000313|EMBL:BAE59951.1, ECO:0000313|Proteomes:UP000006564};
RN [1] {ECO:0000313|EMBL:BAE59951.1, ECO:0000313|Proteomes:UP000006564}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC 42149 / RIB 40 {ECO:0000313|Proteomes:UP000006564};
RX PubMed=16372010; DOI=10.1038/nature04300;
RA Machida M., Asai K., Sano M., Tanaka T., Kumagai T., Terai G., Kusumoto K.,
RA Arima T., Akita O., Kashiwagi Y., Abe K., Gomi K., Horiuchi H.,
RA Kitamoto K., Kobayashi T., Takeuchi M., Denning D.W., Galagan J.E.,
RA Nierman W.C., Yu J., Archer D.B., Bennett J.W., Bhatnagar D.,
RA Cleveland T.E., Fedorova N.D., Gotoh O., Horikawa H., Hosoyama A.,
RA Ichinomiya M., Igarashi R., Iwashita K., Juvvadi P.R., Kato M., Kato Y.,
RA Kin T., Kokubun A., Maeda H., Maeyama N., Maruyama J., Nagasaki H.,
RA Nakajima T., Oda K., Okada K., Paulsen I., Sakamoto K., Sawano T.,
RA Takahashi M., Takase K., Terabayashi Y., Wortman J., Yamada O.,
RA Yamagata Y., Anazawa H., Hata Y., Koide Y., Komori T., Koyama Y.,
RA Minetoki T., Suharnan S., Tanaka A., Isono K., Kuhara S., Ogasawara N.,
RA Kikuchi H.;
RT "Genome sequencing and analysis of Aspergillus oryzae.";
RL Nature 438:1157-1161(2005).
CC -!- SIMILARITY: Belongs to the ATP-dependent AMP-binding enzyme family.
CC {ECO:0000256|ARBA:ARBA00006432}.
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DR EMBL; AP007159; BAE59951.1; -; Genomic_DNA.
DR AlphaFoldDB; Q2UER4; -.
DR STRING; 510516.Q2UER4; -.
DR EnsemblFungi; BAE59951; BAE59951; AO090026000514.
DR HOGENOM; CLU_000022_46_3_1; -.
DR OMA; WRFIRIF; -.
DR OrthoDB; 1650656at2759; -.
DR Proteomes; UP000006564; Chromosome 3.
DR Gene3D; 3.30.300.30; -; 1.
DR Gene3D; 3.40.50.12780; N-terminal domain of ligase-like; 1.
DR InterPro; IPR045851; AMP-bd_C_sf.
DR InterPro; IPR020845; AMP-binding_CS.
DR InterPro; IPR000873; AMP-dep_Synth/Lig_com.
DR InterPro; IPR042099; ANL_N_sf.
DR PANTHER; PTHR43107:SF20; FATTY ACID TRANSPORTER_ACYL-COA SYNTHETASE (FAT1), PUTATIVE (AFU_ORTHOLOGUE AFUA_2G11360)-RELATED; 1.
DR PANTHER; PTHR43107; LONG-CHAIN FATTY ACID TRANSPORT PROTEIN; 1.
DR Pfam; PF00501; AMP-binding; 1.
DR SUPFAM; SSF56801; Acetyl-CoA synthetase-like; 1.
DR PROSITE; PS00455; AMP_BINDING; 1.
PE 3: Inferred from homology;
KW Reference proteome {ECO:0000313|Proteomes:UP000006564}.
FT DOMAIN 61..364
FT /note="AMP-dependent synthetase/ligase"
FT /evidence="ECO:0000259|Pfam:PF00501"
SQ SEQUENCE 623 AA; 69359 MW; 6CD8E7E7C50211D1 CRC64;
MASALSVGAA AYLNAKLAIS TDISTIFNDR AFTARFGQRI AQLGDTTTIY KMLERVIEVD
GHGSSDALWF ENKTWTYSQL KDLVDRFATV LHGRNINSGD FVGVFTTNSI EMVVTIYALS
KLGCVAALIN TNLRDDTFIH CLNVSGSKFI ISTPDLSEFV CSDLPHIALN ISSFDGESAG
TTELITAAQL QQLIPLGLIP AKRSPSDFCA LIYTSGTTGK PKACAIRNMM TLVTSNPLST
DANNQSKYFP LRTYSPLPLF HGTAFFTGLC YSLGNASTLC LRRKFSASQF WKDVHDSRAT
RILYIGELCR YLLSTPPSPY DQDHSCIVAT GNGLRGEIWE RFRQRFAVPE IREFYRSTEG
VAKFDNHGVG AWGAGKIGFS GPIRRFFEDD VFIVKYDTET EMPYRDPKTG FCVRAKLGEE
GEAIGRVRNR GLLTEYLHNE DATEKKLLRD VFEKGDIFQR TGDLVVQDRD GWVKFQDRVG
DTFRWKGENV SAGEIRDHIC RIPSVHDAVV YGVKLQGYDG QAGAAGVTLE ESSAAVESEF
IKNLYRELKK KGVPSYALPR LVRLTEKVAT GVTFKQAKGD LAKKGWDPRG DWKGDKLYWL
NGKTYEKLDE RSWSSIESGQ AKL
//
