ID Q2USF8_ASPOR Unreviewed; 1046 AA.
AC Q2USF8;
DT 24-JAN-2006, integrated into UniProtKB/TrEMBL.
DT 24-JAN-2006, sequence version 1.
DT 27-MAR-2024, entry version 96.
DE RecName: Full=CNH domain-containing protein {ECO:0000259|PROSITE:PS50219};
GN ORFNames=AO090005000443 {ECO:0000313|EMBL:BAE55507.1};
OS Aspergillus oryzae (strain ATCC 42149 / RIB 40) (Yellow koji mold).
OC Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Eurotiomycetes;
OC Eurotiomycetidae; Eurotiales; Aspergillaceae; Aspergillus;
OC Aspergillus subgen. Circumdati.
OX NCBI_TaxID=510516 {ECO:0000313|EMBL:BAE55507.1, ECO:0000313|Proteomes:UP000006564};
RN [1] {ECO:0000313|EMBL:BAE55507.1, ECO:0000313|Proteomes:UP000006564}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC 42149 / RIB 40 {ECO:0000313|Proteomes:UP000006564};
RX PubMed=16372010; DOI=10.1038/nature04300;
RA Machida M., Asai K., Sano M., Tanaka T., Kumagai T., Terai G., Kusumoto K.,
RA Arima T., Akita O., Kashiwagi Y., Abe K., Gomi K., Horiuchi H.,
RA Kitamoto K., Kobayashi T., Takeuchi M., Denning D.W., Galagan J.E.,
RA Nierman W.C., Yu J., Archer D.B., Bennett J.W., Bhatnagar D.,
RA Cleveland T.E., Fedorova N.D., Gotoh O., Horikawa H., Hosoyama A.,
RA Ichinomiya M., Igarashi R., Iwashita K., Juvvadi P.R., Kato M., Kato Y.,
RA Kin T., Kokubun A., Maeda H., Maeyama N., Maruyama J., Nagasaki H.,
RA Nakajima T., Oda K., Okada K., Paulsen I., Sakamoto K., Sawano T.,
RA Takahashi M., Takase K., Terabayashi Y., Wortman J., Yamada O.,
RA Yamagata Y., Anazawa H., Hata Y., Koide Y., Komori T., Koyama Y.,
RA Minetoki T., Suharnan S., Tanaka A., Isono K., Kuhara S., Ogasawara N.,
RA Kikuchi H.;
RT "Genome sequencing and analysis of Aspergillus oryzae.";
RL Nature 438:1157-1161(2005).
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DR EMBL; AP007151; BAE55507.1; -; Genomic_DNA.
DR AlphaFoldDB; Q2USF8; -.
DR STRING; 510516.Q2USF8; -.
DR EnsemblFungi; BAE55507; BAE55507; AO090005000443.
DR HOGENOM; CLU_004190_1_1_1; -.
DR OMA; LFRLPNF; -.
DR OrthoDB; 38195at2759; -.
DR Proteomes; UP000006564; Chromosome 1.
DR GO; GO:0005737; C:cytoplasm; IEA:UniProt.
DR GO; GO:0043231; C:intracellular membrane-bounded organelle; IEA:UniProt.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR GO; GO:0006886; P:intracellular protein transport; IEA:UniProtKB-UniRule.
DR GO; GO:0016192; P:vesicle-mediated transport; IEA:InterPro.
DR InterPro; IPR000547; Clathrin_H-chain/VPS_repeat.
DR InterPro; IPR001180; CNH_dom.
DR InterPro; IPR032914; Vam6/VPS39/TRAP1.
DR InterPro; IPR019452; VPS39/TGF_beta_rcpt-assoc_1.
DR InterPro; IPR019453; VPS39/TGF_beta_rcpt-assoc_2.
DR InterPro; IPR036322; WD40_repeat_dom_sf.
DR PANTHER; PTHR12894; CNH DOMAIN CONTAINING; 1.
DR PANTHER; PTHR12894:SF27; TRANSFORMING GROWTH FACTOR-BETA RECEPTOR-ASSOCIATED PROTEIN 1; 1.
DR Pfam; PF00780; CNH; 1.
DR Pfam; PF10366; Vps39_1; 1.
DR Pfam; PF10367; Vps39_2; 1.
DR SUPFAM; SSF50978; WD40 repeat-like; 1.
DR PROSITE; PS50236; CHCR; 1.
DR PROSITE; PS50219; CNH; 1.
PE 4: Predicted;
KW Reference proteome {ECO:0000313|Proteomes:UP000006564}.
FT DOMAIN 18..359
FT /note="CNH"
FT /evidence="ECO:0000259|PROSITE:PS50219"
FT REGION 50..90
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 468..488
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 523..543
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 50..70
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 1046 AA; 116803 MW; 40AD9EBC45DF8695 CRC64;
MLSAFTARPL VELKPRDKSR IESVLAYGDR LLVGLNNGSL RIYRINEVSP DEQNHDDSNN
HSHDEQGGGG TLKKGDSGRP GTTDSVAKPK QTDLLRELEK FSRYKIEQLA LIKEAKLLIS
LSGGYISIHD LQTYEIQEQL TKTKGATTFN VTSNIVNDPE TGVPSIVSRL AVAVKRKILL
WSWRDMELDS DAAEMTLVSG IKTLTWVSGT KLVAGLGSNF VMVDIETSVV TDLAGPGSIG
GLGGQETSRL AGVGVASMSY IGIGGAAPKP LATRLSEGQI LLAKDINTHF IDINGNSLGR
RQIPWSHAPA NIGYSYPFLL ALHDPSKGVM EVRNPETLSL LQSVALPSAS ILHFPQPSIS
LAHAGKGFLV GSDRTIWRME ALSYDTQIDT LVEKGYLDEA ISLTSMLEDA LLSDKKGRLR
TIKMEKAQGL FTLRKYRDSM DLFTEISAPP ETVIRLYPKV IAGDLSSIDE EEESEESITD
DPSKTNEGQV QLDGAITENA SAPKTLNHAP SVRSLLRTRT DDWSDAGSIR GKPTEEARNE
KPLHGKDLLT AVRELQKYLA DVRRRFQRFL NPDGTLKTID SPSDAANDEF TDSVMKLLDI
TKDIHDHEFA EKLHEEARLV DTTFFRVCMY ATPALAGSLF RIANFCDPEV VMEKLEETGR
YNDLIDFLYG KKMHRQALEL LQRFGQAESE TETAPQLHGP KRTVAYLQNL APDRIDLILE
FAEWPVREDP NLGMEIFLAD TENAETLPRH QVLEFLRGID PNLAVRYLEH VIGELNDMTP
DLHQKLLTFY MDRLKKNGSD SWAFPNGEER ILWRNKFLEM LRSSSQYSPA KILDSLDRDD
PEFFEARAIV FSKMGQHRQA LEIYVFKLED YAKAEEYCNH FHKTDDITAE AAPLSVLDSD
DKPSIHLTLL SLYLTPPHGY ERRYGPALEI LAKHGSRLPP SSALELIPES LPVKELDFYF
KGRMRAATSA LNESRIVASL QKAQNFKTEA QLMVGEGTDG KSCRMRHVTI TEERICGICH
KRIGGSVINV FPEYVFHAVF VSSFFH
//
