ID Q2W9U1_MAGSA Unreviewed; 652 AA.
AC Q2W9U1;
DT 10-JAN-2006, integrated into UniProtKB/TrEMBL.
DT 10-JAN-2006, sequence version 1.
DT 27-MAR-2024, entry version 92.
DE SubName: Full=Acyl-coenzyme A synthetase/AMP-(Fatty) acid ligase {ECO:0000313|EMBL:BAE49384.1};
GN OrderedLocusNames=amb0580 {ECO:0000313|EMBL:BAE49384.1};
OS Magnetospirillum magneticum (strain AMB-1 / ATCC 700264).
OC Bacteria; Pseudomonadota; Alphaproteobacteria; Rhodospirillales;
OC Magnetospirillaceae; Paramagnetospirillum.
OX NCBI_TaxID=342108 {ECO:0000313|EMBL:BAE49384.1, ECO:0000313|Proteomes:UP000007058};
RN [1] {ECO:0000313|EMBL:BAE49384.1, ECO:0000313|Proteomes:UP000007058}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=AMB-1 / ATCC 700264 {ECO:0000313|Proteomes:UP000007058};
RX PubMed=16303747; DOI=10.1093/dnares/dsi002;
RA Matsunaga T., Okamura Y., Fukuda Y., Wahyudi A.T., Murase Y., Takeyama H.;
RT "Complete genome sequence of the facultative anaerobic magnetotactic
RT bacterium Magnetospirillum sp. strain AMB-1.";
RL DNA Res. 12:157-166(2005).
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR EMBL; AP007255; BAE49384.1; -; Genomic_DNA.
DR RefSeq; WP_011383023.1; NC_007626.1.
DR AlphaFoldDB; Q2W9U1; -.
DR STRING; 342108.amb0580; -.
DR KEGG; mag:amb0580; -.
DR HOGENOM; CLU_000022_3_3_5; -.
DR OrthoDB; 4471305at2; -.
DR Proteomes; UP000007058; Chromosome.
DR GO; GO:0030729; F:acetoacetate-CoA ligase activity; IEA:InterPro.
DR GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR GO; GO:0006629; P:lipid metabolic process; IEA:InterPro.
DR CDD; cd05943; AACS; 1.
DR Gene3D; 3.30.300.30; -; 1.
DR Gene3D; 3.40.50.12780; N-terminal domain of ligase-like; 1.
DR InterPro; IPR005914; Acac_CoA_synth.
DR InterPro; IPR032387; ACAS_N.
DR InterPro; IPR025110; AMP-bd_C.
DR InterPro; IPR045851; AMP-bd_C_sf.
DR InterPro; IPR020845; AMP-binding_CS.
DR InterPro; IPR000873; AMP-dep_Synth/Lig_com.
DR InterPro; IPR042099; ANL_N_sf.
DR NCBIfam; TIGR01217; ac_ac_CoA_syn; 1.
DR PANTHER; PTHR42921; ACETOACETYL-COA SYNTHETASE; 1.
DR PANTHER; PTHR42921:SF1; ACETOACETYL-COA SYNTHETASE; 1.
DR Pfam; PF16177; ACAS_N; 1.
DR Pfam; PF00501; AMP-binding; 1.
DR Pfam; PF13193; AMP-binding_C; 1.
DR SUPFAM; SSF56801; Acetyl-CoA synthetase-like; 1.
DR PROSITE; PS00455; AMP_BINDING; 1.
PE 4: Predicted;
KW Acetylation {ECO:0000256|ARBA:ARBA00022990};
KW ATP-binding {ECO:0000256|ARBA:ARBA00022840};
KW Ligase {ECO:0000256|ARBA:ARBA00022598, ECO:0000313|EMBL:BAE49384.1};
KW Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741};
KW Reference proteome {ECO:0000313|Proteomes:UP000007058}.
FT DOMAIN 36..93
FT /note="Acetyl-coenzyme A synthetase N-terminal"
FT /evidence="ECO:0000259|Pfam:PF16177"
FT DOMAIN 103..469
FT /note="AMP-dependent synthetase/ligase"
FT /evidence="ECO:0000259|Pfam:PF00501"
FT DOMAIN 545..614
FT /note="AMP-binding enzyme C-terminal"
FT /evidence="ECO:0000259|Pfam:PF13193"
SQ SEQUENCE 652 AA; 71393 MW; 69334E27CCEE2A48 CRC64;
MSVLLWQPSK ERAEASALAR FMRRADARFQ VGATDYAGLW RWSVDRPDQF WSLVWDEVGI
IGDRPDGGVV VDDAGRMPGA RWFPEARLNF AENLLRRDDG GDALVFWGED KVKRRLSFAE
LRALVSRLQQ ALSAAGVGKG DRVAGYMPNM PESVAFMLAV ASLGAIWSSA SPDFGVQGVL
DRFGQIAPKV LVAAEGYFYS GKAHDCLEKL AAIVPGIPSL ERVVVVPYTR EAADLSGVDK
AVHLGDFLAP FPAKAVEFLR LPFDHPLYIM YSSGTTGAPK CIVHSAGGSL IQQLKEHRLH
CDVRKDDRVF YFTTCGWMMW NWLVAGLGAE ATLLLYDGNP SHLGGNILFD FADAEGMTLF
GTSAKWIDAI AKSGLEPIKT HSLATVRTIC STGSVLAPEG FDYVYAKVKA DVQLASISGG
TDIISCFMLG NPLVPVYRGE IQCRGLGMKV EVFDENGQSL AGSKGELVCT RAFPSMPVGF
WNDDDGAKYR AAYFEKFPGI WTHGDWVELN PETGGIIVFG RSDATLNPGG VRIGTAEIYR
QVEQIDDVLE SLVIGQDWQA DVRVVLFVRL RDGVTLSPEL ETRIKKRIRD NTTPRHVPAK
VVQVADIPRT KSGKIVELAV RDVVHGRAVK NKEALANPEA LDLFAGRAEL EE
//
