ID Q2Y774_NITMU Unreviewed; 894 AA.
AC Q2Y774;
DT 20-DEC-2005, integrated into UniProtKB/TrEMBL.
DT 20-DEC-2005, sequence version 1.
DT 27-MAR-2024, entry version 88.
DE SubName: Full=Choline dehydrogenase {ECO:0000313|EMBL:SEF87295.1};
GN OrderedLocusNames=Nmul_A2104 {ECO:0000313|EMBL:ABB75397.1};
GN ORFNames=SAMN05216403_11273 {ECO:0000313|EMBL:SEF87295.1};
OS Nitrosospira multiformis (strain ATCC 25196 / NCIMB 11849 / C 71).
OC Bacteria; Pseudomonadota; Betaproteobacteria; Nitrosomonadales;
OC Nitrosomonadaceae; Nitrosospira.
OX NCBI_TaxID=323848 {ECO:0000313|EMBL:ABB75397.1, ECO:0000313|Proteomes:UP000002718};
RN [1] {ECO:0000313|Proteomes:UP000002718}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC 25196 / NCIMB 11849 / C 71
RC {ECO:0000313|Proteomes:UP000002718};
RA Copeland A., Lucas S., Lapidus A., Barry K., Detter J.C., Glavina T.,
RA Hammon N., Israni S., Pitluck S., Chain P., Malfatti S., Shin M.,
RA Vergez L., Schmutz J., Larimer F., Land M., Hauser L., Kyrpides N.,
RA Lykidis A., Richardson P.;
RT "Complete sequence of chromosome 1 of Nitrosospira multiformis ATCC
RT 25196.";
RL Submitted (AUG-2005) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|EMBL:ABB75397.1}
RP NUCLEOTIDE SEQUENCE.
RC STRAIN=ATCC 25196 {ECO:0000313|EMBL:ABB75397.1};
RG US DOE Joint Genome Institute;
RA Copeland A., Lucas S., Lapidus A., Barry K., Detter J.C., Glavina T.,
RA Hammon N., Israni S., Pitluck S., Chain P., Malfatti S., Shin M.,
RA Vergez L., Schmutz J., Larimer F., Land M., Hauser L., Kyrpides N.,
RA Lykidis A., Richardson P.;
RT "Complete sequence of Chromosome 1 of Nitrosospira multiformis ATCC
RT 25196.";
RL Submitted (AUG-2005) to the EMBL/GenBank/DDBJ databases.
RN [3] {ECO:0000313|EMBL:ABB75397.1, ECO:0000313|Proteomes:UP000002718}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC 25196 {ECO:0000313|EMBL:ABB75397.1}, and ATCC 25196 /
RC NCIMB 11849 / C 71 {ECO:0000313|Proteomes:UP000002718};
RX PubMed=18390676; DOI=10.1128/AEM.02722-07;
RA Norton J.M., Klotz M.G., Stein L.Y., Arp D.J., Bottomley P.J., Chain P.S.,
RA Hauser L.J., Land M.L., Larimer F.W., Shin M.W., Starkenburg S.R.;
RT "Complete genome sequence of Nitrosospira multiformis, an ammonia-oxidizing
RT bacterium from the soil environment.";
RL Appl. Environ. Microbiol. 74:3559-3572(2008).
RN [4] {ECO:0000313|EMBL:SEF87295.1, ECO:0000313|Proteomes:UP000236751}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Nl13 {ECO:0000313|EMBL:SEF87295.1,
RC ECO:0000313|Proteomes:UP000236751};
RA de Groot N.N.;
RL Submitted (OCT-2016) to the EMBL/GenBank/DDBJ databases.
CC -!- COFACTOR:
CC Name=FAD; Xref=ChEBI:CHEBI:57692;
CC Evidence={ECO:0000256|ARBA:ARBA00001974};
CC -!- SIMILARITY: Belongs to the GMC oxidoreductase family.
CC {ECO:0000256|ARBA:ARBA00010790}.
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DR EMBL; CP000103; ABB75397.1; -; Genomic_DNA.
DR EMBL; FNVK01000012; SEF87295.1; -; Genomic_DNA.
DR RefSeq; WP_011381406.1; NZ_FNVK01000012.1.
DR AlphaFoldDB; Q2Y774; -.
DR STRING; 323848.Nmul_A2104; -.
DR KEGG; nmu:Nmul_A2104; -.
DR eggNOG; COG2303; Bacteria.
DR HOGENOM; CLU_350808_0_0_4; -.
DR OrthoDB; 9787779at2; -.
DR Proteomes; UP000002718; Chromosome.
DR Proteomes; UP000236751; Unassembled WGS sequence.
DR GO; GO:0016787; F:hydrolase activity; IEA:InterPro.
DR GO; GO:0016614; F:oxidoreductase activity, acting on CH-OH group of donors; IEA:InterPro.
DR Gene3D; 3.50.50.60; FAD/NAD(P)-binding domain; 2.
DR InterPro; IPR010496; 3-keto-disaccharide_hydrolase.
DR InterPro; IPR036188; FAD/NAD-bd_sf.
DR InterPro; IPR007867; GMC_OxRtase_C.
DR PANTHER; PTHR42784; PYRANOSE 2-OXIDASE; 1.
DR PANTHER; PTHR42784:SF1; PYRANOSE 2-OXIDASE; 1.
DR Pfam; PF06439; 3keto-disac_hyd; 1.
DR Pfam; PF05199; GMC_oxred_C; 1.
DR SUPFAM; SSF51905; FAD/NAD(P)-binding domain; 1.
PE 3: Inferred from homology;
KW Reference proteome {ECO:0000313|Proteomes:UP000002718}.
FT DOMAIN 531..651
FT /note="Glucose-methanol-choline oxidoreductase C-terminal"
FT /evidence="ECO:0000259|Pfam:PF05199"
FT DOMAIN 671..892
FT /note="3-keto-disaccharide hydrolase"
FT /evidence="ECO:0000259|Pfam:PF06439"
FT REGION 589..614
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 894 AA; 97887 MW; FC85FDE2C5949A00 CRC64;
MPLIAPDYNT AFTRDVLGRY DCNTFDEALV TIDPNARAAA GLPGRGDLRP FDFIIIGGGT
FGAAIAEHLW FRSTQRSERI LVLEAGPFLL PEHVQNLPML GLDTAGARKD HSLQGEVWGL
AWNSSDPFGF PGLAYCLGGR SIYWGGWLPR LLDAEMPKDV WPKGVLDDLT AKVLPDGRKG
YFRQSSDQIG VTETNDFIFG DLHRAMRQQL FGALSSIPDV YDLALLPDHP AVYYGNTPVT
INDLAKLLGI DKLPSPPPSI QKLRDEAKLE APLAVQGQVG HAGFFPFNKF SAVPLLMKAA
REASTQTPFD GVINRLDDVK KRLMVVERCH VTQLNTVNTE GGRRVSEIVT ERGVLPVSPD
SKVIIALGTI ESARLALTSF GTDGKIGRNL IAHLRSNVDF RVPRAALAAL PPAVKALEAS
ALFVKGRHEF KKADGSADGF AHFHFQITAS GLGTNGTNSE AELFKKIPDI DLFDAHKNAT
DTHVVITIRG IGEMEPKNDS DFGSSVTLDL DPQQKDEFQA RRAFVNLQPS SRDYELWDAM
DKASDEVAKV FANGQKIDVI KNGNVIVTNI DPSSLATVLP YKFSDQAGRG RRDGLGTTHH
EAGTLRMGED PNKSVTDPDC RFHNVTNTYV AGPALFPTMG SPNPMLTGIA LVRRLGDHLM
PEPPLLVSEP GFTYLFDGSD AQFANWEMAG GGSFSRFGRT IIAQQNEKGM GLLFYKPKPF
EDFTLRLDFL LPHPRGNGND NSGVFVRFRD SRLPDPAPDP VDPADNAAFV AVHTGFEIQI
DEEARGDTRF GEPDGSFFAR TGAIYKIKSL GTGEGQQNYQ NNISLAARQW HHYEIEVKKQ
DYVVRLNGQE VTRFKRSPSD TARGNPPSVD PNSGYIGLQT HTGNVAFANV RINA
//
