ID Q2Y8M1_NITMU Unreviewed; 226 AA.
AC Q2Y8M1;
DT 20-DEC-2005, integrated into UniProtKB/TrEMBL.
DT 20-DEC-2005, sequence version 1.
DT 27-MAR-2024, entry version 82.
DE SubName: Full=5-methylcytosine-specific restriction enzyme A {ECO:0000313|EMBL:SEG08343.1};
DE SubName: Full=HNH nuclease {ECO:0000313|EMBL:ABB74900.1};
GN OrderedLocusNames=Nmul_A1599 {ECO:0000313|EMBL:ABB74900.1};
GN ORFNames=SAMN05216403_12813 {ECO:0000313|EMBL:SEG08343.1};
OS Nitrosospira multiformis (strain ATCC 25196 / NCIMB 11849 / C 71).
OC Bacteria; Pseudomonadota; Betaproteobacteria; Nitrosomonadales;
OC Nitrosomonadaceae; Nitrosospira.
OX NCBI_TaxID=323848 {ECO:0000313|EMBL:ABB74900.1, ECO:0000313|Proteomes:UP000002718};
RN [1] {ECO:0000313|Proteomes:UP000002718}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC 25196 / NCIMB 11849 / C 71
RC {ECO:0000313|Proteomes:UP000002718};
RA Copeland A., Lucas S., Lapidus A., Barry K., Detter J.C., Glavina T.,
RA Hammon N., Israni S., Pitluck S., Chain P., Malfatti S., Shin M.,
RA Vergez L., Schmutz J., Larimer F., Land M., Hauser L., Kyrpides N.,
RA Lykidis A., Richardson P.;
RT "Complete sequence of chromosome 1 of Nitrosospira multiformis ATCC
RT 25196.";
RL Submitted (AUG-2005) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|EMBL:ABB74900.1}
RP NUCLEOTIDE SEQUENCE.
RC STRAIN=ATCC 25196 {ECO:0000313|EMBL:ABB74900.1};
RG US DOE Joint Genome Institute;
RA Copeland A., Lucas S., Lapidus A., Barry K., Detter J.C., Glavina T.,
RA Hammon N., Israni S., Pitluck S., Chain P., Malfatti S., Shin M.,
RA Vergez L., Schmutz J., Larimer F., Land M., Hauser L., Kyrpides N.,
RA Lykidis A., Richardson P.;
RT "Complete sequence of Chromosome 1 of Nitrosospira multiformis ATCC
RT 25196.";
RL Submitted (AUG-2005) to the EMBL/GenBank/DDBJ databases.
RN [3] {ECO:0000313|EMBL:ABB74900.1, ECO:0000313|Proteomes:UP000002718}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC 25196 {ECO:0000313|EMBL:ABB74900.1}, and ATCC 25196 /
RC NCIMB 11849 / C 71 {ECO:0000313|Proteomes:UP000002718};
RX PubMed=18390676; DOI=10.1128/AEM.02722-07;
RA Norton J.M., Klotz M.G., Stein L.Y., Arp D.J., Bottomley P.J., Chain P.S.,
RA Hauser L.J., Land M.L., Larimer F.W., Shin M.W., Starkenburg S.R.;
RT "Complete genome sequence of Nitrosospira multiformis, an ammonia-oxidizing
RT bacterium from the soil environment.";
RL Appl. Environ. Microbiol. 74:3559-3572(2008).
RN [4] {ECO:0000313|EMBL:SEG08343.1, ECO:0000313|Proteomes:UP000236751}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Nl13 {ECO:0000313|EMBL:SEG08343.1,
RC ECO:0000313|Proteomes:UP000236751};
RA de Groot N.N.;
RL Submitted (OCT-2016) to the EMBL/GenBank/DDBJ databases.
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DR EMBL; CP000103; ABB74900.1; -; Genomic_DNA.
DR EMBL; FNVK01000028; SEG08343.1; -; Genomic_DNA.
DR RefSeq; WP_011380927.1; NZ_FNVK01000028.1.
DR AlphaFoldDB; Q2Y8M1; -.
DR STRING; 323848.Nmul_A1599; -.
DR REBASE; 11586; NmfMcrAP.
DR KEGG; nmu:Nmul_A1599; -.
DR eggNOG; COG1403; Bacteria.
DR HOGENOM; CLU_072764_0_0_4; -.
DR OrthoDB; 9802640at2; -.
DR Proteomes; UP000002718; Chromosome.
DR Proteomes; UP000236751; Unassembled WGS sequence.
DR GO; GO:0004519; F:endonuclease activity; IEA:InterPro.
DR GO; GO:0003676; F:nucleic acid binding; IEA:InterPro.
DR GO; GO:0008270; F:zinc ion binding; IEA:InterPro.
DR CDD; cd00085; HNHc; 1.
DR Gene3D; 1.10.30.50; -; 1.
DR InterPro; IPR002711; HNH.
DR InterPro; IPR003615; HNH_nuc.
DR Pfam; PF01844; HNH; 1.
DR SMART; SM00507; HNHc; 1.
PE 4: Predicted;
KW Reference proteome {ECO:0000313|Proteomes:UP000002718}.
FT DOMAIN 142..201
FT /note="HNH nuclease"
FT /evidence="ECO:0000259|SMART:SM00507"
SQ SEQUENCE 226 AA; 25219 MW; 6501D895DE774052 CRC64;
MDDVSWSDEE LKASIEAYVE MQRNERTGQL IVKKQYYKKL VEMFGRSERV FESLMQNISY
VLSLMGRGWM SGLKPARDIG PLVAARIEQL LEQISGQKAV PVAAFEIAVR EAAEQKDLPK
PSGNPRPKRR RISVAQLERD PNVKAWVLQQ AAGTCESCEK PAPFQGADGS PYLELHYVQG
LADGGADAVS NAVALCPNCH REIHYGANAQ AVEAWLYDTV QRLERD
//
