ID Q2YC39_NITMU Unreviewed; 684 AA.
AC Q2YC39;
DT 20-DEC-2005, integrated into UniProtKB/TrEMBL.
DT 20-DEC-2005, sequence version 1.
DT 27-MAR-2024, entry version 99.
DE SubName: Full=Nitroreductase family protein {ECO:0000313|EMBL:SEF39802.1};
DE SubName: Full=UBA/THIF-type NAD/FAD binding fold protein {ECO:0000313|EMBL:ABB73682.1};
GN OrderedLocusNames=Nmul_A0374 {ECO:0000313|EMBL:ABB73682.1};
GN ORFNames=SAMN05216403_10195 {ECO:0000313|EMBL:SEF39802.1};
OS Nitrosospira multiformis (strain ATCC 25196 / NCIMB 11849 / C 71).
OC Bacteria; Pseudomonadota; Betaproteobacteria; Nitrosomonadales;
OC Nitrosomonadaceae; Nitrosospira.
OX NCBI_TaxID=323848 {ECO:0000313|EMBL:ABB73682.1, ECO:0000313|Proteomes:UP000002718};
RN [1] {ECO:0000313|EMBL:ABB73682.1}
RP NUCLEOTIDE SEQUENCE.
RC STRAIN=ATCC 25196 {ECO:0000313|EMBL:ABB73682.1};
RG US DOE Joint Genome Institute;
RA Copeland A., Lucas S., Lapidus A., Barry K., Detter J.C., Glavina T.,
RA Hammon N., Israni S., Pitluck S., Chain P., Malfatti S., Shin M.,
RA Vergez L., Schmutz J., Larimer F., Land M., Hauser L., Kyrpides N.,
RA Lykidis A., Richardson P.;
RT "Complete sequence of Chromosome 1 of Nitrosospira multiformis ATCC
RT 25196.";
RL Submitted (AUG-2005) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|Proteomes:UP000002718}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC 25196 / NCIMB 11849 / C 71
RC {ECO:0000313|Proteomes:UP000002718};
RA Copeland A., Lucas S., Lapidus A., Barry K., Detter J.C., Glavina T.,
RA Hammon N., Israni S., Pitluck S., Chain P., Malfatti S., Shin M.,
RA Vergez L., Schmutz J., Larimer F., Land M., Hauser L., Kyrpides N.,
RA Lykidis A., Richardson P.;
RT "Complete sequence of chromosome 1 of Nitrosospira multiformis ATCC
RT 25196.";
RL Submitted (AUG-2005) to the EMBL/GenBank/DDBJ databases.
RN [3] {ECO:0000313|EMBL:ABB73682.1, ECO:0000313|Proteomes:UP000002718}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC 25196 {ECO:0000313|EMBL:ABB73682.1}, and ATCC 25196 /
RC NCIMB 11849 / C 71 {ECO:0000313|Proteomes:UP000002718};
RX PubMed=18390676; DOI=10.1128/AEM.02722-07;
RA Norton J.M., Klotz M.G., Stein L.Y., Arp D.J., Bottomley P.J., Chain P.S.,
RA Hauser L.J., Land M.L., Larimer F.W., Shin M.W., Starkenburg S.R.;
RT "Complete genome sequence of Nitrosospira multiformis, an ammonia-oxidizing
RT bacterium from the soil environment.";
RL Appl. Environ. Microbiol. 74:3559-3572(2008).
RN [4] {ECO:0000313|EMBL:SEF39802.1, ECO:0000313|Proteomes:UP000236751}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Nl13 {ECO:0000313|EMBL:SEF39802.1,
RC ECO:0000313|Proteomes:UP000236751};
RA de Groot N.N.;
RL Submitted (OCT-2016) to the EMBL/GenBank/DDBJ databases.
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DR EMBL; CP000103; ABB73682.1; -; Genomic_DNA.
DR EMBL; FNVK01000001; SEF39802.1; -; Genomic_DNA.
DR RefSeq; WP_011379736.1; NZ_FNVK01000001.1.
DR AlphaFoldDB; Q2YC39; -.
DR STRING; 323848.Nmul_A0374; -.
DR KEGG; nmu:Nmul_A0374; -.
DR eggNOG; COG0476; Bacteria.
DR eggNOG; COG0778; Bacteria.
DR HOGENOM; CLU_020676_0_0_4; -.
DR OrthoDB; 272552at2; -.
DR Proteomes; UP000002718; Chromosome.
DR Proteomes; UP000236751; Unassembled WGS sequence.
DR GO; GO:0016491; F:oxidoreductase activity; IEA:InterPro.
DR GO; GO:0008641; F:ubiquitin-like modifier activating enzyme activity; IEA:InterPro.
DR CDD; cd01483; E1_enzyme_family; 1.
DR Gene3D; 3.40.50.720; NAD(P)-binding Rossmann-like Domain; 1.
DR Gene3D; 3.40.109.10; NADH Oxidase; 2.
DR InterPro; IPR000415; Nitroreductase-like.
DR InterPro; IPR045886; ThiF/MoeB/HesA.
DR InterPro; IPR000594; ThiF_NAD_FAD-bd.
DR InterPro; IPR035985; Ubiquitin-activating_enz.
DR PANTHER; PTHR43267; TRNA THREONYLCARBAMOYLADENOSINE DEHYDRATASE; 1.
DR PANTHER; PTHR43267:SF1; TRNA THREONYLCARBAMOYLADENOSINE DEHYDRATASE; 1.
DR Pfam; PF00899; ThiF; 1.
DR SUPFAM; SSF69572; Activating enzymes of the ubiquitin-like proteins; 1.
PE 4: Predicted;
KW Reference proteome {ECO:0000313|Proteomes:UP000002718}.
FT DOMAIN 13..265
FT /note="THIF-type NAD/FAD binding fold"
FT /evidence="ECO:0000259|Pfam:PF00899"
FT REGION 290..319
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 294..311
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 684 AA; 76548 MW; A36A80AD98AE637E CRC64;
MVQDFSYREA TSRNIGWVTP VEQEILRYKR IAIAGLGGVG GIHLLTLARL GIGAFHIADF
DVFDLVNFNR QVGATVSSLN RPKSEVLAAM ARDINPELNI KIFPRGVNPD NLPEFFEDVD
LYIDGLDFFA FSARAVTFSA CEERGIPAIT AAPLGMGSAL LNFLPGKMTF EEYFQWGDLP
EVEKALRFLI GLAPTGLHAR YLLDPSSINL KERRGPSTIM GCQLCAGIAA TEALKILLNR
GTVLAAPHGV HFDAYRNKLI RTWRPGGNSN PLQQFSLAIA RRRLSKKNTN KLFGDPEPYS
STGTIIPSES TGCEDESKRP PELKSYTLIE QILDLARWAP SGDNTQPWRF QIVGDNSLTI
HGFDTRDHCV YDLDGRPSQI SIGALLETIS IAATGHGLKT SIQRRPDCSD TKPTFDIHFG
SDPHLKPDPL IPYIRYRSVQ RRPMSTRPLT GREKSALEAA VKPQYDILWL EGFSRRLEMA
RFLFDNAKLR LIMPEAYQVH RAIIQWNSRY SADKVPDQAL GVDPFTARLM HWIMGSWDRV
EFFNTFLAGT WAPRLQMDLI PAMACGGHFV ILAPHAPRSI DDYVSAGRVM QRFWLTATKL
GLQLQPEITP LVFARYSRES IPFSKTKQCI TLATSLTRRL GHILGEEVAT RAVFMGRIGA
GKRPASRSIR LELEQMLWRL RAGA
//
