ID Q2YRC7_BRUA2 Unreviewed; 221 AA.
AC Q2YRC7;
DT 07-FEB-2006, integrated into UniProtKB/TrEMBL.
DT 07-FEB-2006, sequence version 1.
DT 27-MAR-2024, entry version 90.
DE SubName: Full=Thiamine-phosphate pyrophosphorylase, putative {ECO:0000313|EMBL:CAJ11675.1};
DE EC=2.5.1.3 {ECO:0000313|EMBL:CAJ11675.1};
GN OrderedLocusNames=BAB1_1719 {ECO:0000313|EMBL:CAJ11675.1};
OS Brucella abortus (strain 2308).
OC Bacteria; Pseudomonadota; Alphaproteobacteria; Hyphomicrobiales;
OC Brucellaceae; Brucella/Ochrobactrum group; Brucella.
OX NCBI_TaxID=359391 {ECO:0000313|EMBL:CAJ11675.1, ECO:0000313|Proteomes:UP000002719};
RN [1] {ECO:0000313|EMBL:CAJ11675.1, ECO:0000313|Proteomes:UP000002719}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=2308 {ECO:0000313|EMBL:CAJ11675.1,
RC ECO:0000313|Proteomes:UP000002719};
RX PubMed=16299333; DOI=10.1128/IAI.73.12.8353-8361.2005;
RG Microbial Genomics Group;
RG Lawrence Livermore National Laboratory;
RG and the Genome Analysis Group;
RG Oak Ridge National Laboratory;
RA Chain P., Comerci D.J., Tolmasky M.E., Larimer F.W., Malfatti S.,
RA Vergez L.M., Aguero F., Land M.L., Ugalde R.A., Garcia E.;
RT "Whole-genome analyses of speciation events in pathogenic Brucellae.";
RL Infect. Immun. 73:8353-8361(2005).
CC -!- PATHWAY: Cofactor biosynthesis; thiamine diphosphate biosynthesis.
CC {ECO:0000256|ARBA:ARBA00004948}.
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DR EMBL; AM040264; CAJ11675.1; -; Genomic_DNA.
DR RefSeq; WP_002964797.1; NZ_KN046823.1.
DR AlphaFoldDB; Q2YRC7; -.
DR STRING; 359391.BAB1_1719; -.
DR GeneID; 58775283; -.
DR KEGG; bmf:BAB1_1719; -.
DR PATRIC; fig|359391.11.peg.234; -.
DR HOGENOM; CLU_018272_3_1_5; -.
DR PhylomeDB; Q2YRC7; -.
DR Proteomes; UP000002719; Chromosome I.
DR GO; GO:0004789; F:thiamine-phosphate diphosphorylase activity; IEA:UniProtKB-EC.
DR GO; GO:0009228; P:thiamine biosynthetic process; IEA:UniProtKB-KW.
DR CDD; cd00564; TMP_TenI; 1.
DR Gene3D; 3.20.20.70; Aldolase class I; 1.
DR InterPro; IPR013785; Aldolase_TIM.
DR InterPro; IPR036206; ThiamineP_synth_sf.
DR InterPro; IPR022998; ThiamineP_synth_TenI.
DR PANTHER; PTHR20857:SF15; THIAMINE BIOSYNTHETIC BIFUNCTIONAL ENZYME; 1.
DR PANTHER; PTHR20857; THIAMINE-PHOSPHATE PYROPHOSPHORYLASE; 1.
DR Pfam; PF02581; TMP-TENI; 1.
DR SUPFAM; SSF51391; Thiamin phosphate synthase; 1.
PE 4: Predicted;
KW Reference proteome {ECO:0000313|Proteomes:UP000002719};
KW Thiamine biosynthesis {ECO:0000256|ARBA:ARBA00022977};
KW Transferase {ECO:0000313|EMBL:CAJ11675.1}.
FT DOMAIN 16..195
FT /note="Thiamine phosphate synthase/TenI"
FT /evidence="ECO:0000259|Pfam:PF02581"
SQ SEQUENCE 221 AA; 23260 MW; 9E922D59975AD087 CRC64;
MNTRAPQTEP ERCRIVLVAP PIADGAALAK LLTAALSGGD VASVILDTGD LDEATFQAVA
EKTVPVIQEK GVAALILNDT RIAGRVGADG IHIEGKPADL AEAIEKHAPK MIVGTGNLRD
RHGAMEVGEL QPDYLFFGKI GADNKPDAHP RNLSLAGWWA EMVEIPCIAQ AGSALESIVR
AAETGADFVA LGRAVFDAQD PAEAVAQANR LLDEKAPRFE N
//
