ID Q32CT2_SHIDS Unreviewed; 432 AA.
AC Q32CT2;
DT 06-DEC-2005, integrated into UniProtKB/TrEMBL.
DT 06-DEC-2005, sequence version 1.
DT 27-MAR-2024, entry version 105.
DE SubName: Full=Alpha-ketoglutarate permease {ECO:0000313|EMBL:ABB62873.1};
GN Name=kgtP {ECO:0000313|EMBL:ABB62873.1};
GN OrderedLocusNames=SDY_2830 {ECO:0000313|EMBL:ABB62873.1};
OS Shigella dysenteriae serotype 1 (strain Sd197).
OC Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
OC Enterobacteriaceae; Shigella.
OX NCBI_TaxID=300267 {ECO:0000313|EMBL:ABB62873.1, ECO:0000313|Proteomes:UP000002716};
RN [1] {ECO:0000313|EMBL:ABB62873.1, ECO:0000313|Proteomes:UP000002716}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Sd197 {ECO:0000313|EMBL:ABB62873.1,
RC ECO:0000313|Proteomes:UP000002716};
RX PubMed=16275786; DOI=10.1093/nar/gki954;
RA Yang F., Yang J., Zhang X., Chen L., Jiang Y., Yan Y., Tang X., Wang J.,
RA Xiong Z., Dong J., Xue Y., Zhu Y., Xu X., Sun L., Chen S., Nie H., Peng J.,
RA Xu J., Wang Y., Yuan Z., Wen Y., Yao Z., Shen Y., Qiang B., Hou Y., Yu J.,
RA Jin Q.;
RT "Genome dynamics and diversity of Shigella species, the etiologic agents of
RT bacillary dysentery.";
RL Nucleic Acids Res. 33:6445-6458(2005).
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-
CC pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
CC -!- SIMILARITY: Belongs to the major facilitator superfamily. Metabolite:H+
CC Symporter (MHS) family (TC 2.A.1.6) family.
CC {ECO:0000256|ARBA:ARBA00008240}.
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DR EMBL; CP000034; ABB62873.1; -; Genomic_DNA.
DR RefSeq; WP_000841103.1; NC_007606.1.
DR RefSeq; YP_404364.1; NC_007606.1.
DR AlphaFoldDB; Q32CT2; -.
DR SMR; Q32CT2; -.
DR STRING; 300267.SDY_2830; -.
DR EnsemblBacteria; ABB62873; ABB62873; SDY_2830.
DR GeneID; 75206281; -.
DR KEGG; sdy:SDY_2830; -.
DR PATRIC; fig|300267.13.peg.3407; -.
DR HOGENOM; CLU_001265_39_0_6; -.
DR Proteomes; UP000002716; Chromosome.
DR GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-KW.
DR GO; GO:0022857; F:transmembrane transporter activity; IEA:InterPro.
DR CDD; cd17367; MFS_KgtP; 1.
DR Gene3D; 1.20.1250.20; MFS general substrate transporter like domains; 1.
DR InterPro; IPR011701; MFS.
DR InterPro; IPR020846; MFS_dom.
DR InterPro; IPR036259; MFS_trans_sf.
DR InterPro; IPR004736; MHS_symport.
DR InterPro; IPR005829; Sugar_transporter_CS.
DR NCBIfam; TIGR00883; 2A0106; 1.
DR PANTHER; PTHR43528; ALPHA-KETOGLUTARATE PERMEASE; 1.
DR PANTHER; PTHR43528:SF1; ALPHA-KETOGLUTARATE PERMEASE; 1.
DR Pfam; PF07690; MFS_1; 1.
DR SUPFAM; SSF103473; MFS general substrate transporter; 1.
DR PROSITE; PS50850; MFS; 1.
DR PROSITE; PS00216; SUGAR_TRANSPORT_1; 1.
DR PROSITE; PS00217; SUGAR_TRANSPORT_2; 1.
PE 3: Inferred from homology;
KW Cell inner membrane {ECO:0000256|ARBA:ARBA00022519};
KW Cell membrane {ECO:0000256|ARBA:ARBA00022475};
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000002716};
KW Symport {ECO:0000256|ARBA:ARBA00022847};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}; Transport {ECO:0000256|ARBA:ARBA00022448}.
FT TRANSMEM 21..42
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 62..84
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 96..116
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 122..139
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 160..183
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 195..214
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 244..266
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 278..299
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 311..331
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 337..360
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 372..393
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 405..423
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 23..428
FT /note="Major facilitator superfamily (MFS) profile"
FT /evidence="ECO:0000259|PROSITE:PS50850"
SQ SEQUENCE 432 AA; 47052 MW; 264B8473195765DB CRC64;
MAESTVTADS KLTSSDTRRR IWAIVGASSG NLVEWFDFYV YSFCSLYFAH IFFPSGNTTT
QLLQTAGVFA AGFLMRPIGG WLFGRIADKH GRKKSMLLSV CMMCFGSLVI ACLPGYETIG
TWAPALLLLA RLFQGLSVGG EYGTSATYMS EVAVEGRKGF YASFQYVTLI GGQLLALLVV
VVLQHTMEDA ALREWGWRIP FALGAVLAVV ALWLRRQLDE TSQQETRALK EAGSLKGLWR
NRRAFIMVLG FTAAGSLCFY TFTTYMQKYL VNTAGMHANV ASGIMTAALF VFMLIQPLIG
ALSDKIGRRT SMLCFGSLAA IFTVPILSAL QNVSSPYAAF GLVMCALLIV SFYTSISGIL
KAEMFPAQVR ALGVGLSYAV ANAIFGGSAE YVALSLKSIG METAFFWYVT LMAVVAFLVS
LMLHRKGKGM RL
//
