ID Q383Y0_TRYB2 Unreviewed; 343 AA.
AC Q383Y0;
DT 22-NOV-2005, integrated into UniProtKB/TrEMBL.
DT 22-NOV-2005, sequence version 1.
DT 24-JAN-2024, entry version 74.
DE RecName: Full=CobW/HypB/UreG nucleotide-binding domain-containing protein {ECO:0000259|Pfam:PF02492};
GN ORFNames=Tb11.01.1250 {ECO:0000313|EMBL:EAN79901.1};
OS Trypanosoma brucei brucei (strain 927/4 GUTat10.1).
OC Eukaryota; Discoba; Euglenozoa; Kinetoplastea; Metakinetoplastina;
OC Trypanosomatida; Trypanosomatidae; Trypanosoma.
OX NCBI_TaxID=185431 {ECO:0000313|EMBL:EAN79901.1, ECO:0000313|Proteomes:UP000008524};
RN [1] {ECO:0000313|EMBL:EAN79901.1, ECO:0000313|Proteomes:UP000008524}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=927/4 GUTat10.1 {ECO:0000313|EMBL:EAN79901.1,
RC ECO:0000313|Proteomes:UP000008524};
RX PubMed=16020726; DOI=10.1126/science.1112642;
RA Berriman M., Ghedin E., Hertz-Fowler C., Blandin G., Renauld H.,
RA Bartholomeu D.C., Lennard N.J., Caler E., Hamlin N.E., Haas B., Bohme U.,
RA Hannick L., Aslett M.A., Shallom J., Marcello L., Hou L., Wickstead B.,
RA Alsmark U.C., Arrowsmith C., Atkin R.J., Barron A.J., Bringaud F.,
RA Brooks K., Carrington M., Cherevach I., Chillingworth T.J., Churcher C.,
RA Clark L.N., Corton C.H., Cronin A., Davies R.M., Doggett J., Djikeng A.,
RA Feldblyum T., Field M.C., Fraser A., Goodhead I., Hance Z., Harper D.,
RA Harris B.R., Hauser H., Hostetler J., Ivens A., Jagels K., Johnson D.,
RA Johnson J., Jones K., Kerhornou A.X., Koo H., Larke N., Landfear S.,
RA Larkin C., Leech V., Line A., Lord A., Macleod A., Mooney P.J., Moule S.,
RA Martin D.M., Morgan G.W., Mungall K., Norbertczak H., Ormond D., Pai G.,
RA Peacock C.S., Peterson J., Quail M.A., Rabbinowitsch E., Rajandream M.A.,
RA Reitter C., Salzberg S.L., Sanders M., Schobel S., Sharp S., Simmonds M.,
RA Simpson A.J., Tallon L., Turner C.M., Tait A., Tivey A.R., Van Aken S.,
RA Walker D., Wanless D., Wang S., White B., White O., Whitehead S.,
RA Woodward J., Wortman J., Adams M.D., Embley T.M., Gull K., Ullu E.,
RA Barry J.D., Fairlamb A.H., Opperdoes F., Barrell B.G., Donelson J.E.,
RA Hall N., Fraser C.M., Melville S.E., El-Sayed N.M.;
RT "The genome of the African trypanosome Trypanosoma brucei.";
RL Science 309:416-422(2005).
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DR EMBL; CH464491; EAN79901.1; -; Genomic_DNA.
DR RefSeq; XP_829013.1; XM_823920.1.
DR AlphaFoldDB; Q383Y0; -.
DR STRING; 185431.Q383Y0; -.
DR PaxDb; 5691-EAN79901; -.
DR GeneID; 3664161; -.
DR KEGG; tbr:Tb11.01.1250; -.
DR VEuPathDB; TriTrypDB:Tb927.11.9490; -.
DR eggNOG; KOG2743; Eukaryota.
DR InParanoid; Q383Y0; -.
DR OrthoDB; 1010489at2759; -.
DR Proteomes; UP000008524; Chromosome 11 Scaffold 1.
DR GO; GO:0005737; C:cytoplasm; IBA:GO_Central.
DR CDD; cd03112; CobW-like; 1.
DR Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 1.
DR InterPro; IPR003495; CobW/HypB/UreG_dom.
DR InterPro; IPR027417; P-loop_NTPase.
DR PANTHER; PTHR13748:SF31; COBW DOMAIN-CONTAINING PROTEIN 1-RELATED; 1.
DR PANTHER; PTHR13748; COBW-RELATED; 1.
DR Pfam; PF02492; cobW; 1.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
PE 4: Predicted;
KW Reference proteome {ECO:0000313|Proteomes:UP000008524}.
FT DOMAIN 15..198
FT /note="CobW/HypB/UreG nucleotide-binding"
FT /evidence="ECO:0000259|Pfam:PF02492"
SQ SEQUENCE 343 AA; 38123 MW; 7D826C6984BC445F CRC64;
MSDDECPELV SAKVPVTILT GFLGSGKTTL LHYVLSAEHN LRIAVIVNEF EFGKTIEKGL
TLKSSQKPDD EWLELDNGCM CCTAQTQTVQ ALEKLMQRKG TFDLVLVETS GLADPAPVAS
MFWQDEALCG SLYLSGIVTL VDAKNICKYL RDPDVAGEAT RQILMADRIV LNKCDLATEE
EKNEAVVSVR QINPIVQVLP ATFSVLNNLR EVIMLNTTRQ AMELDHLHSS GPSSITAMSL
EFFEQPNFLA VSDRSDVDMI CRDMLYMEHD PPFEVVRCKA ALWMRKGDHY SLLQLQTIGD
LFDVTPMEGQ SVPLGCSRVL VLGKQLNENV LRGIFLKYLR GCA
//
