ID Q386C6_TRYB2 Unreviewed; 433 AA.
AC Q386C6;
DT 22-NOV-2005, integrated into UniProtKB/TrEMBL.
DT 22-NOV-2005, sequence version 1.
DT 24-JAN-2024, entry version 82.
DE SubName: Full=Actin, putative {ECO:0000313|EMBL:EAN79355.1};
GN ORFNames=Tb11.02.1380 {ECO:0000313|EMBL:EAN79355.1};
OS Trypanosoma brucei brucei (strain 927/4 GUTat10.1).
OC Eukaryota; Discoba; Euglenozoa; Kinetoplastea; Metakinetoplastina;
OC Trypanosomatida; Trypanosomatidae; Trypanosoma.
OX NCBI_TaxID=185431 {ECO:0000313|EMBL:EAN79355.1, ECO:0000313|Proteomes:UP000008524};
RN [1] {ECO:0000313|EMBL:EAN79355.1, ECO:0000313|Proteomes:UP000008524}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=927/4 GUTat10.1 {ECO:0000313|EMBL:EAN79355.1,
RC ECO:0000313|Proteomes:UP000008524};
RX PubMed=16020726; DOI=10.1126/science.1112642;
RA Berriman M., Ghedin E., Hertz-Fowler C., Blandin G., Renauld H.,
RA Bartholomeu D.C., Lennard N.J., Caler E., Hamlin N.E., Haas B., Bohme U.,
RA Hannick L., Aslett M.A., Shallom J., Marcello L., Hou L., Wickstead B.,
RA Alsmark U.C., Arrowsmith C., Atkin R.J., Barron A.J., Bringaud F.,
RA Brooks K., Carrington M., Cherevach I., Chillingworth T.J., Churcher C.,
RA Clark L.N., Corton C.H., Cronin A., Davies R.M., Doggett J., Djikeng A.,
RA Feldblyum T., Field M.C., Fraser A., Goodhead I., Hance Z., Harper D.,
RA Harris B.R., Hauser H., Hostetler J., Ivens A., Jagels K., Johnson D.,
RA Johnson J., Jones K., Kerhornou A.X., Koo H., Larke N., Landfear S.,
RA Larkin C., Leech V., Line A., Lord A., Macleod A., Mooney P.J., Moule S.,
RA Martin D.M., Morgan G.W., Mungall K., Norbertczak H., Ormond D., Pai G.,
RA Peacock C.S., Peterson J., Quail M.A., Rabbinowitsch E., Rajandream M.A.,
RA Reitter C., Salzberg S.L., Sanders M., Schobel S., Sharp S., Simmonds M.,
RA Simpson A.J., Tallon L., Turner C.M., Tait A., Tivey A.R., Van Aken S.,
RA Walker D., Wanless D., Wang S., White B., White O., Whitehead S.,
RA Woodward J., Wortman J., Adams M.D., Embley T.M., Gull K., Ullu E.,
RA Barry J.D., Fairlamb A.H., Opperdoes F., Barrell B.G., Donelson J.E.,
RA Hall N., Fraser C.M., Melville S.E., El-Sayed N.M.;
RT "The genome of the African trypanosome Trypanosoma brucei.";
RL Science 309:416-422(2005).
CC -!- SIMILARITY: Belongs to the actin family.
CC {ECO:0000256|RuleBase:RU000487}.
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DR EMBL; CH464491; EAN79355.1; -; Genomic_DNA.
DR RefSeq; XP_828467.1; XM_823374.1.
DR AlphaFoldDB; Q386C6; -.
DR SMR; Q386C6; -.
DR STRING; 185431.Q386C6; -.
DR PaxDb; 5691-EAN79355; -.
DR GeneID; 3664842; -.
DR KEGG; tbr:Tb11.02.1380; -.
DR VEuPathDB; TriTrypDB:Tb927.11.3880; -.
DR eggNOG; KOG0676; Eukaryota.
DR InParanoid; Q386C6; -.
DR OrthoDB; 152039at2759; -.
DR Proteomes; UP000008524; Chromosome 11 Scaffold 1.
DR GO; GO:0015629; C:actin cytoskeleton; ISM:GeneDB.
DR GO; GO:0005930; C:axoneme; IDA:GeneDB.
DR GO; GO:0005737; C:cytoplasm; IDA:GeneDB.
DR GO; GO:0005200; F:structural constituent of cytoskeleton; ISM:GeneDB.
DR Gene3D; 3.30.420.40; -; 2.
DR InterPro; IPR004000; Actin.
DR InterPro; IPR043129; ATPase_NBD.
DR PANTHER; PTHR11937; ACTIN; 1.
DR PANTHER; PTHR11937:SF508; PUTATIVE-RELATED; 1.
DR Pfam; PF00022; Actin; 1.
DR PRINTS; PR00190; ACTIN.
DR SMART; SM00268; ACTIN; 1.
DR SUPFAM; SSF53067; Actin-like ATPase domain; 2.
PE 3: Inferred from homology;
KW Reference proteome {ECO:0000313|Proteomes:UP000008524}.
SQ SEQUENCE 433 AA; 47560 MW; FA9F328357964CEE CRC64;
MVCSTERAPV VILDGGSHHL RAGYASDGAP RLDIPALVGH PRNRGVAVAA GMNEYEIGDV
ALAKRGMLTV SSPIESGRVV SWENMEKLWG HVMYSELRVR PESHCFIVPQ SVNTPASQKE
KTLELMMETF HVHSLFLGAS QVLSLYSYGL TTGLVIDSGK DRTMAVPVHE GYALGRHVAE
SDVAGEKLTE YFASLLRLEG YSFGTPMEMQ VLNNAKEDLC YVKPPIFNMT GPSAFFSPSE
FPGECDYDLS LEGAPGEGFE DGREDHSSDE RVFYLPDGNA IPISTHRSLT TEALFDFGIL
GSQYVPKSRY MTELGEIFQP SFPMGVSWLA FAAINNCQPV IRAQLYASIV LSGGNVSFPG
TRERIETEVT QLYRETHTSE AVTPIAVNDI PCRVYSAWVG GSMLAGTSMF PHLAVSRQEY
EEQGHRVVHC KCQ
//
