ID Q38BB1_TRYB2 Unreviewed; 499 AA.
AC Q38BB1;
DT 22-NOV-2005, integrated into UniProtKB/TrEMBL.
DT 22-NOV-2005, sequence version 1.
DT 24-JAN-2024, entry version 108.
DE SubName: Full=TPR-repeat-containing chaperone protein DNAJ, putative {ECO:0000313|EMBL:EAN77909.1};
GN ORFNames=Tb10.70.2300 {ECO:0000313|EMBL:EAN77909.1};
OS Trypanosoma brucei brucei (strain 927/4 GUTat10.1).
OC Eukaryota; Discoba; Euglenozoa; Kinetoplastea; Metakinetoplastina;
OC Trypanosomatida; Trypanosomatidae; Trypanosoma.
OX NCBI_TaxID=185431 {ECO:0000313|EMBL:EAN77909.1, ECO:0000313|Proteomes:UP000008524};
RN [1] {ECO:0000313|EMBL:EAN77909.1, ECO:0000313|Proteomes:UP000008524}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=927/4 GUTat10.1 {ECO:0000313|EMBL:EAN77909.1,
RC ECO:0000313|Proteomes:UP000008524};
RX PubMed=16020726; DOI=10.1126/science.1112642;
RA Berriman M., Ghedin E., Hertz-Fowler C., Blandin G., Renauld H.,
RA Bartholomeu D.C., Lennard N.J., Caler E., Hamlin N.E., Haas B., Bohme U.,
RA Hannick L., Aslett M.A., Shallom J., Marcello L., Hou L., Wickstead B.,
RA Alsmark U.C., Arrowsmith C., Atkin R.J., Barron A.J., Bringaud F.,
RA Brooks K., Carrington M., Cherevach I., Chillingworth T.J., Churcher C.,
RA Clark L.N., Corton C.H., Cronin A., Davies R.M., Doggett J., Djikeng A.,
RA Feldblyum T., Field M.C., Fraser A., Goodhead I., Hance Z., Harper D.,
RA Harris B.R., Hauser H., Hostetler J., Ivens A., Jagels K., Johnson D.,
RA Johnson J., Jones K., Kerhornou A.X., Koo H., Larke N., Landfear S.,
RA Larkin C., Leech V., Line A., Lord A., Macleod A., Mooney P.J., Moule S.,
RA Martin D.M., Morgan G.W., Mungall K., Norbertczak H., Ormond D., Pai G.,
RA Peacock C.S., Peterson J., Quail M.A., Rabbinowitsch E., Rajandream M.A.,
RA Reitter C., Salzberg S.L., Sanders M., Schobel S., Sharp S., Simmonds M.,
RA Simpson A.J., Tallon L., Turner C.M., Tait A., Tivey A.R., Van Aken S.,
RA Walker D., Wanless D., Wang S., White B., White O., Whitehead S.,
RA Woodward J., Wortman J., Adams M.D., Embley T.M., Gull K., Ullu E.,
RA Barry J.D., Fairlamb A.H., Opperdoes F., Barrell B.G., Donelson J.E.,
RA Hall N., Fraser C.M., Melville S.E., El-Sayed N.M.;
RT "The genome of the African trypanosome Trypanosoma brucei.";
RL Science 309:416-422(2005).
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DR EMBL; CM000208; EAN77909.1; -; Genomic_DNA.
DR RefSeq; XP_822737.1; XM_817644.1.
DR AlphaFoldDB; Q38BB1; -.
DR STRING; 185431.Q38BB1; -.
DR PaxDb; 5691-EAN77909; -.
DR GeneID; 3663137; -.
DR KEGG; tbr:Tb10.70.2300; -.
DR VEuPathDB; TriTrypDB:Tb927.10.4900; -.
DR eggNOG; KOG0550; Eukaryota.
DR InParanoid; Q38BB1; -.
DR OMA; KMCLGLD; -.
DR OrthoDB; 5473367at2759; -.
DR Proteomes; UP000008524; Chromosome 10.
DR GO; GO:0005737; C:cytoplasm; IDA:GeneDB.
DR GO; GO:0006457; P:protein folding; ISM:GeneDB.
DR CDD; cd06257; DnaJ; 1.
DR Gene3D; 1.10.287.110; DnaJ domain; 1.
DR Gene3D; 1.25.40.10; Tetratricopeptide repeat domain; 1.
DR InterPro; IPR001623; DnaJ_domain.
DR InterPro; IPR018253; DnaJ_domain_CS.
DR InterPro; IPR036869; J_dom_sf.
DR InterPro; IPR011990; TPR-like_helical_dom_sf.
DR InterPro; IPR019734; TPR_repeat.
DR PANTHER; PTHR44200; DNAJ HOMOLOG SUBFAMILY C MEMBER 7; 1.
DR PANTHER; PTHR44200:SF1; DNAJ HOMOLOG SUBFAMILY C MEMBER 7; 1.
DR Pfam; PF00226; DnaJ; 1.
DR Pfam; PF13181; TPR_8; 2.
DR PRINTS; PR00625; JDOMAIN.
DR SMART; SM00271; DnaJ; 1.
DR SMART; SM00028; TPR; 6.
DR SUPFAM; SSF46565; Chaperone J-domain; 1.
DR SUPFAM; SSF48452; TPR-like; 3.
DR PROSITE; PS00636; DNAJ_1; 1.
DR PROSITE; PS50076; DNAJ_2; 1.
DR PROSITE; PS50005; TPR; 2.
PE 4: Predicted;
KW Reference proteome {ECO:0000313|Proteomes:UP000008524};
KW TPR repeat {ECO:0000256|PROSITE-ProRule:PRU00339}.
FT REPEAT 246..279
FT /note="TPR"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00339"
FT REPEAT 318..351
FT /note="TPR"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00339"
FT DOMAIN 369..440
FT /note="J"
FT /evidence="ECO:0000259|PROSITE:PS50076"
SQ SEQUENCE 499 AA; 55927 MW; 4E202BAC73E1B099 CRC64;
MEPDDGVASW MELREEGNKA FKSEAYANAV KLYSEAIKLN SKEAALFSNR SAAYIKMKEY
QKAVLDAEAA IANDKTFVKG YSRLHNALCH LGRFREATQK LKEALVVLEA CGASPEDKKQ
IQELHRTAEE GQRGFEAGQR LLEERNFLAA ERELVKAAQL FPDCAIVGIM LGESQASLYP
ERVIRSLTAL SSAHADDTYY LYVRALASYY SGQSGLNNAQ SILRHTIELD PDNRKATELL
KKIRAVESQK TEGNAAFKEK RFTAAVNCYK AAIEVDPSNI RMTAVLRGNQ AAAKMELKEY
SSALLDCDFA IKNGAESAKL YARRSRIHEA LENYDDALRD IQRAAEMDPS YNGEAQQMKI
SAKRAKRKDY YKILGLPQGE SDDSSIKRAY KKGCLQWHPD KWAHATEEEK AHAEKMFKEV
GEAFSILSDP QKKRLYDSGQ LDDASSPGGT SDFPARQADI FQMMNMMFQG GCGEGGMPSG
FSFTVDPRSR RQKQTFHYR
//
