ID Q38BR4_TRYB2 Unreviewed; 349 AA.
AC Q38BR4;
DT 22-NOV-2005, integrated into UniProtKB/TrEMBL.
DT 22-NOV-2005, sequence version 1.
DT 24-JAN-2024, entry version 78.
DE RecName: Full=DDRGK domain-containing protein 1 {ECO:0008006|Google:ProtNLM};
GN ORFNames=Tb10.70.4110 {ECO:0000313|EMBL:EAN77756.1};
OS Trypanosoma brucei brucei (strain 927/4 GUTat10.1).
OC Eukaryota; Discoba; Euglenozoa; Kinetoplastea; Metakinetoplastina;
OC Trypanosomatida; Trypanosomatidae; Trypanosoma.
OX NCBI_TaxID=185431 {ECO:0000313|EMBL:EAN77756.1, ECO:0000313|Proteomes:UP000008524};
RN [1] {ECO:0000313|EMBL:EAN77756.1, ECO:0000313|Proteomes:UP000008524}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=927/4 GUTat10.1 {ECO:0000313|EMBL:EAN77756.1,
RC ECO:0000313|Proteomes:UP000008524};
RX PubMed=16020726; DOI=10.1126/science.1112642;
RA Berriman M., Ghedin E., Hertz-Fowler C., Blandin G., Renauld H.,
RA Bartholomeu D.C., Lennard N.J., Caler E., Hamlin N.E., Haas B., Bohme U.,
RA Hannick L., Aslett M.A., Shallom J., Marcello L., Hou L., Wickstead B.,
RA Alsmark U.C., Arrowsmith C., Atkin R.J., Barron A.J., Bringaud F.,
RA Brooks K., Carrington M., Cherevach I., Chillingworth T.J., Churcher C.,
RA Clark L.N., Corton C.H., Cronin A., Davies R.M., Doggett J., Djikeng A.,
RA Feldblyum T., Field M.C., Fraser A., Goodhead I., Hance Z., Harper D.,
RA Harris B.R., Hauser H., Hostetler J., Ivens A., Jagels K., Johnson D.,
RA Johnson J., Jones K., Kerhornou A.X., Koo H., Larke N., Landfear S.,
RA Larkin C., Leech V., Line A., Lord A., Macleod A., Mooney P.J., Moule S.,
RA Martin D.M., Morgan G.W., Mungall K., Norbertczak H., Ormond D., Pai G.,
RA Peacock C.S., Peterson J., Quail M.A., Rabbinowitsch E., Rajandream M.A.,
RA Reitter C., Salzberg S.L., Sanders M., Schobel S., Sharp S., Simmonds M.,
RA Simpson A.J., Tallon L., Turner C.M., Tait A., Tivey A.R., Van Aken S.,
RA Walker D., Wanless D., Wang S., White B., White O., Whitehead S.,
RA Woodward J., Wortman J., Adams M.D., Embley T.M., Gull K., Ullu E.,
RA Barry J.D., Fairlamb A.H., Opperdoes F., Barrell B.G., Donelson J.E.,
RA Hall N., Fraser C.M., Melville S.E., El-Sayed N.M.;
RT "The genome of the African trypanosome Trypanosoma brucei.";
RL Science 309:416-422(2005).
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DR EMBL; CM000208; EAN77756.1; -; Genomic_DNA.
DR RefSeq; XP_822584.1; XM_817491.1.
DR AlphaFoldDB; Q38BR4; -.
DR STRING; 185431.Q38BR4; -.
DR PaxDb; 5691-EAN77756; -.
DR GeneID; 3662538; -.
DR KEGG; tbr:Tb10.70.4110; -.
DR VEuPathDB; TriTrypDB:Tb927.10.3330; -.
DR eggNOG; KOG3054; Eukaryota.
DR InParanoid; Q38BR4; -.
DR OMA; QEFIQYI; -.
DR OrthoDB; 197573at2759; -.
DR Proteomes; UP000008524; Chromosome 10.
DR GO; GO:0005783; C:endoplasmic reticulum; IDA:GeneDB.
DR GO; GO:0005635; C:nuclear envelope; IDA:GeneDB.
DR Gene3D; 1.10.10.10; Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain; 1.
DR InterPro; IPR019153; DDRGK_dom-contain.
DR InterPro; IPR036388; WH-like_DNA-bd_sf.
DR InterPro; IPR036390; WH_DNA-bd_sf.
DR PANTHER; PTHR48176; DDRGK DOMAIN-CONTAINING PROTEIN 1; 1.
DR PANTHER; PTHR48176:SF1; DDRGK DOMAIN-CONTAINING PROTEIN 1; 1.
DR Pfam; PF09756; DDRGK; 2.
DR SMART; SM01128; DDRGK; 1.
DR SUPFAM; SSF46785; Winged helix' DNA-binding domain; 1.
PE 4: Predicted;
KW Reference proteome {ECO:0000313|Proteomes:UP000008524}.
FT REGION 32..177
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 72..88
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 104..177
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 349 AA; 40092 MW; 527DF020AB85924D CRC64;
MLLIVFVVGF LLLLTAFVAL QLRRSQQFPT FSDATPSRVA ARRSETRRSQ YNDGDYWSNE
SSDEGSDDDD NDDCEVGHKR EERRKLRGGT SGSAGPLRHR RTRRGAGNAA EADGDGEEDK
NGSQTKLSRL QRKKQEKERE RQERQQAQEA LLENRRVKQE EEQRQQKDRE REEREREIAE
EAALQELREE KKRQEDEEYA KWVEGIGVVE RGEIGDEERK KHDNLVKYLI TMAGNGGERQ
QQRVIDAENF GEGEKVGDET ITRGTESSSR GNILILNDVA RTHGLSVEVT VQVIEKLLED
GVISGVFDDR GKFVMLSEEH YKQIAEFVKL RGRVSMKELA RECNRIIML
//
