GenomeNet

Database: UniProt
Entry: Q39TC9_GEOMG
LinkDB: Q39TC9_GEOMG
Original site: Q39TC9_GEOMG 
ID   Q39TC9_GEOMG            Unreviewed;       296 AA.
AC   Q39TC9;
DT   22-NOV-2005, integrated into UniProtKB/TrEMBL.
DT   22-NOV-2005, sequence version 1.
DT   08-MAY-2019, entry version 89.
DE   SubName: Full=3-hydroxyacyl-CoA dehydrogenase {ECO:0000313|EMBL:ABB32495.1};
GN   OrderedLocusNames=Gmet_2269 {ECO:0000313|EMBL:ABB32495.1};
OS   Geobacter metallireducens (strain GS-15 / ATCC 53774 / DSM 7210).
OC   Bacteria; Proteobacteria; Deltaproteobacteria; Desulfuromonadales;
OC   Geobacteraceae; Geobacter.
OX   NCBI_TaxID=269799 {ECO:0000313|EMBL:ABB32495.1, ECO:0000313|Proteomes:UP000007073};
RN   [1] {ECO:0000313|EMBL:ABB32495.1, ECO:0000313|Proteomes:UP000007073}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=GS-15 / ATCC 53774 / DSM 7210
RC   {ECO:0000313|Proteomes:UP000007073};
RG   US DOE Joint Genome Institute;
RA   Copeland A., Lucas S., Lapidus A., Barry K., Detter J.C., Glavina T.,
RA   Hammon N., Israni S., Pitluck S., Di Bartolo G., Chain P., Schmutz J.,
RA   Larimer F., Land M., Kyrpides N., Ivanova N., Richardson P.;
RT   "Complete sequence of Geobacter metallireducens GS-15.";
RL   Submitted (OCT-2005) to the EMBL/GenBank/DDBJ databases.
RN   [2] {ECO:0000313|EMBL:ABB32495.1, ECO:0000313|Proteomes:UP000007073}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=GS-15 / ATCC 53774 / DSM 7210
RC   {ECO:0000313|Proteomes:UP000007073};
RX   PubMed=19473543; DOI=10.1186/1471-2180-9-109;
RA   Aklujkar M., Krushkal J., DiBartolo G., Lapidus A., Land M.L.,
RA   Lovley D.R.;
RT   "The genome sequence of Geobacter metallireducens: features of
RT   metabolism, physiology and regulation common and dissimilar to
RT   Geobacter sulfurreducens.";
RL   BMC Microbiol. 9:109-109(2009).
CC   -----------------------------------------------------------------------
CC   Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC   Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC   -----------------------------------------------------------------------
DR   EMBL; CP000148; ABB32495.1; -; Genomic_DNA.
DR   STRING; 269799.Gmet_2269; -.
DR   EnsemblBacteria; ABB32495; ABB32495; Gmet_2269.
DR   KEGG; gme:Gmet_2269; -.
DR   eggNOG; ENOG4105DYT; Bacteria.
DR   eggNOG; COG1250; LUCA.
DR   HOGENOM; HOG000141498; -.
DR   KO; K00074; -.
DR   OMA; ESPGFVT; -.
DR   BioCyc; GMET269799:GHNY-2322-MONOMER; -.
DR   Proteomes; UP000007073; Chromosome.
DR   GO; GO:0003857; F:3-hydroxyacyl-CoA dehydrogenase activity; IEA:InterPro.
DR   GO; GO:0070403; F:NAD+ binding; IEA:InterPro.
DR   GO; GO:0006631; P:fatty acid metabolic process; IEA:InterPro.
DR   Gene3D; 1.10.1040.10; -; 1.
DR   InterPro; IPR022694; 3-OHacyl-CoA_DH.
DR   InterPro; IPR006176; 3-OHacyl-CoA_DH_NAD-bd.
DR   InterPro; IPR006108; 3HC_DH_C.
DR   InterPro; IPR008927; 6-PGluconate_DH-like_C_sf.
DR   InterPro; IPR013328; 6PGD_dom2.
DR   InterPro; IPR036291; NAD(P)-bd_dom_sf.
DR   Pfam; PF00725; 3HCDH; 1.
DR   Pfam; PF02737; 3HCDH_N; 1.
DR   PIRSF; PIRSF000105; HCDH; 1.
DR   SUPFAM; SSF48179; SSF48179; 1.
DR   SUPFAM; SSF51735; SSF51735; 1.
PE   4: Predicted;
KW   Complete proteome {ECO:0000313|Proteomes:UP000007073};
KW   NAD {ECO:0000256|PIRSR:PIRSR000105-2};
KW   Reference proteome {ECO:0000313|Proteomes:UP000007073}.
FT   DOMAIN       17    196       3HCDH_N. {ECO:0000259|Pfam:PF02737}.
FT   DOMAIN      199    294       3HCDH. {ECO:0000259|Pfam:PF00725}.
FT   NP_BIND      22     27       NAD. {ECO:0000256|PIRSR:PIRSR000105-2}.
FT   BINDING      45     45       NAD. {ECO:0000256|PIRSR:PIRSR000105-2}.
FT   BINDING     105    105       NAD. {ECO:0000256|PIRSR:PIRSR000105-2}.
FT   BINDING     110    110       NAD. {ECO:0000256|PIRSR:PIRSR000105-2}.
FT   BINDING     132    132       NAD. {ECO:0000256|PIRSR:PIRSR000105-2}.
FT   BINDING     156    156       NAD. {ECO:0000256|PIRSR:PIRSR000105-2}.
FT   BINDING     286    286       NAD. {ECO:0000256|PIRSR:PIRSR000105-2}.
FT   SITE        153    153       Important for catalytic activity.
FT                                {ECO:0000256|PIRSR:PIRSR000105-1}.
SQ   SEQUENCE   296 AA;  32277 MW;  49AF1DD254CB204C CRC64;
     MNSDNKLRGE ESMGIGKVAV IGSGIMGHGI SQVVATAGIN VALNDISDQV LEKAKSHIAA
     SLDRGIQRGK LTEEDKKSIL GRISYTTDIA QAVKDADLVV EAAPENLELK HSIFRKLDQY
     CKPEAILASN TSQYSITELA SVVANPSRVI GMHWFNPPVA MKLIEIIRGL ETSDAVLNEI
     ETFSAAVGKE TVVCKDSQGF ISTRVLVAMR LECYRLVEEG IATPEDIDKT LRLAFGHPMG
     QFELADFSGL DIEPAACEAL TKTFGDRFRA PQILLHRVKA GKLGRKSGEG WYKYDK
//
DBGET integrated database retrieval system