ID Q3ABT7_CARHZ Unreviewed; 550 AA.
AC Q3ABT7;
DT 22-NOV-2005, integrated into UniProtKB/TrEMBL.
DT 22-NOV-2005, sequence version 1.
DT 27-MAR-2024, entry version 112.
DE SubName: Full=DNA polymerase, X family {ECO:0000313|EMBL:ABB14668.1};
GN OrderedLocusNames=CHY_1568 {ECO:0000313|EMBL:ABB14668.1};
OS Carboxydothermus hydrogenoformans (strain ATCC BAA-161 / DSM 6008 /
OS Z-2901).
OC Bacteria; Bacillota; Clostridia; Thermoanaerobacterales;
OC Thermoanaerobacteraceae; Carboxydothermus.
OX NCBI_TaxID=246194 {ECO:0000313|EMBL:ABB14668.1, ECO:0000313|Proteomes:UP000002706};
RN [1] {ECO:0000313|EMBL:ABB14668.1, ECO:0000313|Proteomes:UP000002706}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC BAA-161 / DSM 6008 / Z-2901
RC {ECO:0000313|Proteomes:UP000002706};
RX PubMed=16311624; DOI=10.1371/journal.pgen.0010065;
RA Wu M., Ren Q., Durkin A.S., Daugherty S.C., Brinkac L.M., Dodson R.J.,
RA Madupu R., Sullivan S.A., Kolonay J.F., Haft D.H., Nelson W.C.,
RA Tallon L.J., Jones K.M., Ulrich L.E., Gonzalez J.M., Zhulin I.B.,
RA Robb F.T., Eisen J.A.;
RT "Life in hot carbon monoxide: the complete genome sequence of
RT Carboxydothermus hydrogenoformans Z-2901.";
RL PLoS Genet. 1:563-574(2005).
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DR EMBL; CP000141; ABB14668.1; -; Genomic_DNA.
DR RefSeq; WP_011344472.1; NC_007503.1.
DR AlphaFoldDB; Q3ABT7; -.
DR STRING; 246194.CHY_1568; -.
DR KEGG; chy:CHY_1568; -.
DR eggNOG; COG1387; Bacteria.
DR eggNOG; COG1796; Bacteria.
DR HOGENOM; CLU_017729_1_0_9; -.
DR InParanoid; Q3ABT7; -.
DR OrthoDB; 9808747at2; -.
DR Proteomes; UP000002706; Chromosome.
DR GO; GO:0003677; F:DNA binding; NAS:TIGR.
DR GO; GO:0003887; F:DNA-directed DNA polymerase activity; NAS:TIGR.
DR GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR GO; GO:0006281; P:DNA repair; IEA:InterPro.
DR GO; GO:0006260; P:DNA replication; NAS:TIGR.
DR CDD; cd07436; PHP_PolX; 1.
DR Gene3D; 1.10.150.20; 5' to 3' exonuclease, C-terminal subdomain; 1.
DR Gene3D; 1.10.150.110; DNA polymerase beta, N-terminal domain-like; 1.
DR Gene3D; 3.20.20.140; Metal-dependent hydrolases; 1.
DR InterPro; IPR002054; DNA-dir_DNA_pol_X.
DR InterPro; IPR010996; DNA_pol_b-like_N.
DR InterPro; IPR027421; DNA_pol_lamdba_lyase_dom_sf.
DR InterPro; IPR003583; Hlx-hairpin-Hlx_DNA-bd_motif.
DR InterPro; IPR043519; NT_sf.
DR InterPro; IPR004013; PHP_dom.
DR InterPro; IPR003141; Pol/His_phosphatase_N.
DR InterPro; IPR016195; Pol/histidinol_Pase-like.
DR InterPro; IPR022311; PolX-like.
DR InterPro; IPR047967; PolX_PHP.
DR InterPro; IPR010994; RuvA_2-like.
DR PANTHER; PTHR36928; PHOSPHATASE YCDX-RELATED; 1.
DR PANTHER; PTHR36928:SF1; PHOSPHATASE YCDX-RELATED; 1.
DR Pfam; PF14520; HHH_5; 1.
DR Pfam; PF14716; HHH_8; 1.
DR Pfam; PF02811; PHP; 1.
DR PIRSF; PIRSF005047; UCP005047_YshC; 2.
DR SMART; SM00278; HhH1; 3.
DR SMART; SM00481; POLIIIAc; 1.
DR SMART; SM00483; POLXc; 1.
DR SUPFAM; SSF47802; DNA polymerase beta, N-terminal domain-like; 1.
DR SUPFAM; SSF81301; Nucleotidyltransferase; 1.
DR SUPFAM; SSF89550; PHP domain-like; 1.
DR SUPFAM; SSF47781; RuvA domain 2-like; 1.
PE 4: Predicted;
KW DNA synthesis {ECO:0000256|ARBA:ARBA00022634};
KW Reference proteome {ECO:0000313|Proteomes:UP000002706}.
FT DOMAIN 1..292
FT /note="DNA-directed DNA polymerase X"
FT /evidence="ECO:0000259|SMART:SM00483"
FT DOMAIN 50..69
FT /note="Helix-hairpin-helix DNA-binding motif class 1"
FT /evidence="ECO:0000259|SMART:SM00278"
FT DOMAIN 90..109
FT /note="Helix-hairpin-helix DNA-binding motif class 1"
FT /evidence="ECO:0000259|SMART:SM00278"
FT DOMAIN 125..144
FT /note="Helix-hairpin-helix DNA-binding motif class 1"
FT /evidence="ECO:0000259|SMART:SM00278"
FT DOMAIN 316..395
FT /note="Polymerase/histidinol phosphatase N-terminal"
FT /evidence="ECO:0000259|SMART:SM00481"
SQ SEQUENCE 550 AA; 62304 MW; 4EB177B102B420F1 CRC64;
MISLQLSRIF DEMALMLEYK EENFFKINAY RQAARILRNI KDLERFISED RLEELPGIGK
NLREKILEFY RTGRIGEYEK LREEIPLIIF DLLKIPGIGV KTAKQIYETY RPNTLDEVES
LAKAHKLKEI PGIGSKTEQQ ILVGIASARE WQEKITISLY SRNQTEILEF IKSLPGVEKV
SSTGSLRLKE EIIPYYHFLI IFNGSKEKFT ELMGNFGFKL LDQNDGLLFL APEGYKVKID
FATFNSWGNK LFLTTGPENF VKAIGVLDKS YSDEEMIFQS IGLPYVEPEL RTAEGLLEFL
KEADTDDLIT ASDIKGDLHV HSQHSDGINS IKDLALAAQK LGYEYISVND HSKSLTVAKG
LDEERLLAQI AEIEALNREL EGITVLKGIE VDILKDGSLD LPDKLLAQLD VVVASVHTGF
KLPKEEQTAR IIEAIKNEHV DIIGHPTGRL LGRREQYDVD VEEIIAQAAK YSTALEINSS
PERLDLNDEY VSHARREGVL IAINTDAHDT NRLANDLQFG VTVARKALLT KKDVLNAKDL
KSLKKFLRRK
//
