ID Q3AUS9_SYNS9 Unreviewed; 297 AA.
AC Q3AUS9;
DT 22-NOV-2005, integrated into UniProtKB/TrEMBL.
DT 22-NOV-2005, sequence version 1.
DT 27-MAR-2024, entry version 73.
DE RecName: Full=beta-lactamase {ECO:0000256|ARBA:ARBA00012865};
DE EC=3.5.2.6 {ECO:0000256|ARBA:ARBA00012865};
GN OrderedLocusNames=Syncc9902_1987 {ECO:0000313|EMBL:ABB26945.1};
OS Synechococcus sp. (strain CC9902).
OC Bacteria; Cyanobacteriota; Cyanophyceae; Synechococcales; Synechococcaceae;
OC Synechococcus.
OX NCBI_TaxID=316279 {ECO:0000313|EMBL:ABB26945.1, ECO:0000313|Proteomes:UP000002712};
RN [1] {ECO:0000313|Proteomes:UP000002712}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=CC9902 {ECO:0000313|Proteomes:UP000002712};
RA Copeland A., Lucas S., Lapidus A., Barry K., Detter J.C., Glavina T.,
RA Hammon N., Israni S., Pitluck S., Martinez M., Schmutz J., Larimer F.,
RA Land M., Kyrpides N., Ivanova N., Richardson P.;
RT "Complete sequence of Synechococcus sp. CC9902.";
RL Submitted (AUG-2005) to the EMBL/GenBank/DDBJ databases.
CC -!- CATALYTIC ACTIVITY:
CC Reaction=a beta-lactam + H2O = a substituted beta-amino acid;
CC Xref=Rhea:RHEA:20401, ChEBI:CHEBI:15377, ChEBI:CHEBI:35627,
CC ChEBI:CHEBI:140347; EC=3.5.2.6;
CC Evidence={ECO:0000256|ARBA:ARBA00001526};
CC -!- SIMILARITY: Belongs to the class-A beta-lactamase family.
CC {ECO:0000256|ARBA:ARBA00009009}.
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DR EMBL; CP000097; ABB26945.1; -; Genomic_DNA.
DR RefSeq; WP_011360738.1; NC_007513.1.
DR AlphaFoldDB; Q3AUS9; -.
DR STRING; 316279.Syncc9902_1987; -.
DR KEGG; sye:Syncc9902_1987; -.
DR eggNOG; COG2367; Bacteria.
DR HOGENOM; CLU_924163_0_0_3; -.
DR OrthoDB; 7510992at2; -.
DR Proteomes; UP000002712; Chromosome.
DR GO; GO:0008800; F:beta-lactamase activity; IEA:InterPro.
DR GO; GO:0030655; P:beta-lactam antibiotic catabolic process; IEA:InterPro.
DR GO; GO:0046677; P:response to antibiotic; IEA:UniProtKB-KW.
DR Gene3D; 3.40.710.10; DD-peptidase/beta-lactamase superfamily; 1.
DR InterPro; IPR012338; Beta-lactam/transpept-like.
DR InterPro; IPR045155; Beta-lactam_cat.
DR InterPro; IPR000871; Beta-lactam_class-A.
DR PANTHER; PTHR35333; BETA-LACTAMASE; 1.
DR PANTHER; PTHR35333:SF3; BETA-LACTAMASE2 DOMAIN-CONTAINING PROTEIN; 1.
DR Pfam; PF13354; Beta-lactamase2; 1.
DR SUPFAM; SSF56601; beta-lactamase/transpeptidase-like; 1.
PE 3: Inferred from homology;
KW Antibiotic resistance {ECO:0000256|ARBA:ARBA00023251}.
FT DOMAIN 90..272
FT /note="Beta-lactamase class A catalytic"
FT /evidence="ECO:0000259|Pfam:PF13354"
SQ SEQUENCE 297 AA; 32996 MW; A53ECE2233AF35B7 CRC64;
MAFYRFDPAM ALCLESVLDE LDAEGRPGLR NSLGLTWIRY SDANPEAGDG MGVSWNHQKP
IYPASVVKLF YAVAAEQWLQ RDLIPDSDEL ERALREMIAD SSNDATGLVL DLLTGTTSGP
MLHGEHWLMW QRQRHLVNEW LDTLVWPELE LVNCCQKTWG DGPFGREKAF YGNDNANRNA
LTTAGTARML EAVMTGAVVS PPACRRLRAL LQRSLDPDQR RADPENQVDG FLGEGLPEGV
TLWSKAGWMS QARHDAAWWQ LPDQPPMLLV AFSSGPDHAK DEQLLPALAR ALSAFAG
//
