ID Q3ITE2_NATPD Unreviewed; 170 AA.
AC Q3ITE2;
DT 08-NOV-2005, integrated into UniProtKB/TrEMBL.
DT 08-NOV-2005, sequence version 1.
DT 27-MAR-2024, entry version 93.
DE RecName: Full=Phosphoesterase {ECO:0000256|RuleBase:RU362039};
DE EC=3.1.4.- {ECO:0000256|RuleBase:RU362039};
GN OrderedLocusNames=NP_1002A {ECO:0000313|EMBL:CAI48592.1};
OS Natronomonas pharaonis (strain ATCC 35678 / DSM 2160 / CIP 103997 / JCM
OS 8858 / NBRC 14720 / NCIMB 2260 / Gabara) (Halobacterium pharaonis).
OC Archaea; Euryarchaeota; Stenosarchaea group; Halobacteria; Halobacteriales;
OC Haloarculaceae; Natronomonas.
OX NCBI_TaxID=348780 {ECO:0000313|EMBL:CAI48592.1, ECO:0000313|Proteomes:UP000002698};
RN [1] {ECO:0000313|EMBL:CAI48592.1, ECO:0000313|Proteomes:UP000002698}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC 35678 / DSM 2160 / CIP 103997 / JCM 8858 / NBRC 14720 /
RC NCIMB 2260 / Gabara {ECO:0000313|Proteomes:UP000002698};
RX PubMed=16169924; DOI=10.1101/gr.3952905;
RA Falb M., Pfeiffer F., Palm P., Rodewald K., Hickmann V., Tittor J.,
RA Oesterhelt D.;
RT "Living with two extremes: conclusions from the genome sequence of
RT Natronomonas pharaonis.";
RL Genome Res. 15:1336-1343(2005).
CC -!- COFACTOR:
CC Name=a divalent metal cation; Xref=ChEBI:CHEBI:60240;
CC Evidence={ECO:0000256|RuleBase:RU362039};
CC -!- SIMILARITY: Belongs to the metallophosphoesterase superfamily. YfcE
CC family. {ECO:0000256|RuleBase:RU362039}.
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DR EMBL; CR936257; CAI48592.1; -; Genomic_DNA.
DR RefSeq; WP_011322227.1; NC_007426.1.
DR AlphaFoldDB; Q3ITE2; -.
DR STRING; 348780.NP_1002A; -.
DR EnsemblBacteria; CAI48592; CAI48592; NP_1002A.
DR GeneID; 3701028; -.
DR KEGG; nph:NP_1002A; -.
DR eggNOG; arCOG01141; Archaea.
DR HOGENOM; CLU_063749_4_1_2; -.
DR OrthoDB; 9959at2157; -.
DR Proteomes; UP000002698; Chromosome.
DR GO; GO:0004527; F:exonuclease activity; IEA:UniProtKB-KW.
DR GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR CDD; cd00841; MPP_YfcE; 1.
DR Gene3D; 3.60.21.10; -; 1.
DR InterPro; IPR024654; Calcineurin-like_PHP_lpxH.
DR InterPro; IPR029052; Metallo-depent_PP-like.
DR InterPro; IPR041802; MPP_YfcE.
DR InterPro; IPR000979; Phosphodiesterase_MJ0936/Vps29.
DR NCBIfam; TIGR00040; yfcE; 1.
DR PANTHER; PTHR43165; METALLOPHOSPHOESTERASE; 1.
DR PANTHER; PTHR43165:SF1; PHOSPHODIESTERASE MJ0936; 1.
DR Pfam; PF12850; Metallophos_2; 1.
DR SUPFAM; SSF56300; Metallo-dependent phosphatases; 1.
PE 3: Inferred from homology;
KW Exonuclease {ECO:0000256|ARBA:ARBA00022839};
KW Hydrolase {ECO:0000313|EMBL:CAI48592.1};
KW Metal-binding {ECO:0000256|RuleBase:RU362039};
KW Nuclease {ECO:0000256|ARBA:ARBA00022839};
KW Reference proteome {ECO:0000313|Proteomes:UP000002698}.
FT DOMAIN 1..157
FT /note="Calcineurin-like phosphoesterase"
FT /evidence="ECO:0000259|Pfam:PF12850"
SQ SEQUENCE 170 AA; 18413 MW; 41AF988D4A6C9FC3 CRC64;
MHVGVISDTH DNVPAARAAM DRFEEEGVDT VVHCGDFVAP PLIPFLDRDG IAVHAVRGNN
DGEREGLVDA FDALDGGTFH GRFAELTLGG REFAVLHGEE RPVIDALAAS GEYDYVLHGH
WHVREERTVG ETTVLNPGAH FPTVADEHRT VAVVDTGADE ITFHAIDGER
//
