ID Q3K8Y7_PSEPF Unreviewed; 883 AA.
AC Q3K8Y7;
DT 08-NOV-2005, integrated into UniProtKB/TrEMBL.
DT 08-NOV-2005, sequence version 1.
DT 27-MAR-2024, entry version 135.
DE RecName: Full=histidine kinase {ECO:0000256|ARBA:ARBA00012438};
DE EC=2.7.13.3 {ECO:0000256|ARBA:ARBA00012438};
GN Name=kdpD {ECO:0000313|EMBL:ABA75767.1};
GN OrderedLocusNames=Pfl01_4030 {ECO:0000313|EMBL:ABA75767.1};
OS Pseudomonas fluorescens (strain Pf0-1).
OC Bacteria; Pseudomonadota; Gammaproteobacteria; Pseudomonadales;
OC Pseudomonadaceae; Pseudomonas.
OX NCBI_TaxID=205922 {ECO:0000313|EMBL:ABA75767.1, ECO:0000313|Proteomes:UP000002704};
RN [1] {ECO:0000313|EMBL:ABA75767.1, ECO:0000313|Proteomes:UP000002704}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Pf0-1 {ECO:0000313|EMBL:ABA75767.1,
RC ECO:0000313|Proteomes:UP000002704};
RX PubMed=19432983; DOI=10.1186/gb-2009-10-5-r51;
RA Silby M.W., Cerdeno-Tarraga A.M., Vernikos G.S., Giddens S.R.,
RA Jackson R.W., Preston G.M., Zhang X.X., Moon C.D., Gehrig S.M.,
RA Godfrey S.A., Knight C.G., Malone J.G., Robinson Z., Spiers A.J.,
RA Harris S., Challis G.L., Yaxley A.M., Harris D., Seeger K., Murphy L.,
RA Rutter S., Squares R., Quail M.A., Saunders E., Mavromatis K.,
RA Brettin T.S., Bentley S.D., Hothersall J., Stephens E., Thomas C.M.,
RA Parkhill J., Levy S.B., Rainey P.B., Thomson N.R.;
RT "Genomic and genetic analyses of diversity and plant interactions of
RT Pseudomonas fluorescens.";
RL Genome Biol. 10:R51.1-R51.16(2009).
CC -!- CATALYTIC ACTIVITY:
CC Reaction=ATP + protein L-histidine = ADP + protein N-phospho-L-
CC histidine.; EC=2.7.13.3; Evidence={ECO:0000256|ARBA:ARBA00000085};
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DR EMBL; CP000094; ABA75767.1; -; Genomic_DNA.
DR RefSeq; WP_011335327.1; NC_007492.2.
DR AlphaFoldDB; Q3K8Y7; -.
DR KEGG; pfo:Pfl01_4030; -.
DR eggNOG; COG2205; Bacteria.
DR HOGENOM; CLU_000445_113_2_6; -.
DR Proteomes; UP000002704; Chromosome.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR GO; GO:0000155; F:phosphorelay sensor kinase activity; IEA:InterPro.
DR GO; GO:0034220; P:monoatomic ion transmembrane transport; IEA:UniProtKB-KW.
DR CDD; cd00075; HATPase; 1.
DR CDD; cd00082; HisKA; 1.
DR CDD; cd01987; USP_OKCHK; 1.
DR Gene3D; 1.10.287.130; -; 1.
DR Gene3D; 3.30.450.40; -; 1.
DR Gene3D; 1.20.120.620; Backbone structure of the membrane domain of e. Coli histidine kinase receptor kdpd; 1.
DR Gene3D; 3.30.565.10; Histidine kinase-like ATPase, C-terminal domain; 1.
DR Gene3D; 3.40.50.620; HUPs; 1.
DR Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 1.
DR InterPro; IPR029016; GAF-like_dom_sf.
DR InterPro; IPR003594; HATPase_C.
DR InterPro; IPR036890; HATPase_C_sf.
DR InterPro; IPR005467; His_kinase_dom.
DR InterPro; IPR003661; HisK_dim/P.
DR InterPro; IPR036097; HisK_dim/P_sf.
DR InterPro; IPR038318; KdpD_sf.
DR InterPro; IPR025201; KdpD_TM.
DR InterPro; IPR027417; P-loop_NTPase.
DR InterPro; IPR014729; Rossmann-like_a/b/a_fold.
DR InterPro; IPR004358; Sig_transdc_His_kin-like_C.
DR InterPro; IPR003852; Sig_transdc_His_kinase_KdpD_N.
DR InterPro; IPR006016; UspA.
DR PANTHER; PTHR45569; SENSOR PROTEIN KDPD; 1.
DR PANTHER; PTHR45569:SF1; SENSOR PROTEIN KDPD; 1.
DR Pfam; PF13493; DUF4118; 1.
DR Pfam; PF02518; HATPase_c; 1.
DR Pfam; PF00512; HisKA; 1.
DR Pfam; PF02702; KdpD; 1.
DR Pfam; PF00582; Usp; 1.
DR PRINTS; PR00344; BCTRLSENSOR.
DR SMART; SM00387; HATPase_c; 1.
DR SMART; SM00388; HisKA; 1.
DR SUPFAM; SSF52402; Adenine nucleotide alpha hydrolases-like; 1.
DR SUPFAM; SSF55874; ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase; 1.
DR SUPFAM; SSF55781; GAF domain-like; 1.
DR SUPFAM; SSF47384; Homodimeric domain of signal transducing histidine kinase; 1.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
DR PROSITE; PS50109; HIS_KIN; 1.
PE 4: Predicted;
KW ATP-binding {ECO:0000256|ARBA:ARBA00022840};
KW Ion channel {ECO:0000313|EMBL:ABA75767.1};
KW Ion transport {ECO:0000313|EMBL:ABA75767.1};
KW Kinase {ECO:0000256|ARBA:ARBA00022777, ECO:0000313|EMBL:ABA75767.1};
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741};
KW Phosphoprotein {ECO:0000256|ARBA:ARBA00022553};
KW Transferase {ECO:0000256|ARBA:ARBA00022679, ECO:0000313|EMBL:ABA75767.1};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}; Transport {ECO:0000313|EMBL:ABA75767.1};
KW Two-component regulatory system {ECO:0000256|ARBA:ARBA00023012}.
FT TRANSMEM 418..446
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 466..484
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 658..875
FT /note="Histidine kinase"
FT /evidence="ECO:0000259|PROSITE:PS50109"
SQ SEQUENCE 883 AA; 96064 MW; A833B011E1CD8601 CRC64;
MSDSGRADAL LAELPRDGRG RLKVFLGAAP GVGKTYAMLQ AAHSQLRQGV KVIAGVVETH
GRAETEALLG GLPQLPLVRS EYRGVTLEEM DLDGLLAARP KLVLVDELAH SNAPGSRHAK
RWQDIQELLA AGIDVYTTVN VQHLESLNDQ VRGITGVQVR ETLPDWVLQE AYELLLIDLP
PRELLERLRE GKVYVPEQAR AAIDAFFTQT NLTALRELAM QTAAAQVDND LAQGYRQLGQ
AAPAVRGRLL VGVDGDAQAE RLVRHASRVA QRRHLPWSLV HVDNGSVRDE QSRLRLQSAQ
QLAERLGGEV VLLRAGEVAK TLIQHAAERR ASLVLVGQSR PRLRRRLFGG GLAARLLRQA
HGLEINVLDS DQEQHQPRPR SAPTLVWFDY ALALVATVLA SALAWAVSSV LPLPNISLVF
LAAVLLVAVR SSLGPALACA ALSFLTYDFL FIPPNFSFSI QREEDVLTLL FFLLMAALTG
NLAARQRRQL QALRDTQEET TELLDLSRKL TAATDRQAVV SAAAQHLNGW SDLQLCLLNR
DGQGGWKVET GGPLQFTESE RAAADWAWQH DQPAGMGTGT LPFGRWWWWP LSVEDGPLAL
LGVCAKEGQT LSGQRRRLLT ALSQPLAQAL ARAQLADDLE AARLHGETEQ LRSALLASVS
HDLRTPLTSM RGSIDSLLAL GEAIPLEDRR ELLEGTRDEA ERLDRYIQNL LDMTRLGHGA
LKLARDWVSP ADIVGSALNR LRAVLSSLQV STDVPAELPL LYVHAALIEQ ALVNVLENAA
RFSPSHGRLQ LRAGADDSEV FFSVSDEGPG IPVDERAKIF DMFYTAARGD RGGQGTGLGL
AICQGMVGAH GGRISVGDGI DGRGTCITLH LPLQTQPGMD DEA
//
