ID Q3KFB4_PSEPF Unreviewed; 1162 AA.
AC Q3KFB4;
DT 08-NOV-2005, integrated into UniProtKB/TrEMBL.
DT 08-NOV-2005, sequence version 1.
DT 27-MAR-2024, entry version 126.
DE RecName: Full=Chromosome partition protein Smc {ECO:0000256|HAMAP-Rule:MF_01894};
GN Name=smc {ECO:0000256|HAMAP-Rule:MF_01894};
GN OrderedLocusNames=Pfl01_1799 {ECO:0000313|EMBL:ABA73542.1};
OS Pseudomonas fluorescens (strain Pf0-1).
OC Bacteria; Pseudomonadota; Gammaproteobacteria; Pseudomonadales;
OC Pseudomonadaceae; Pseudomonas.
OX NCBI_TaxID=205922 {ECO:0000313|EMBL:ABA73542.1, ECO:0000313|Proteomes:UP000002704};
RN [1] {ECO:0000313|EMBL:ABA73542.1, ECO:0000313|Proteomes:UP000002704}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Pf0-1 {ECO:0000313|EMBL:ABA73542.1,
RC ECO:0000313|Proteomes:UP000002704};
RX PubMed=19432983; DOI=10.1186/gb-2009-10-5-r51;
RA Silby M.W., Cerdeno-Tarraga A.M., Vernikos G.S., Giddens S.R.,
RA Jackson R.W., Preston G.M., Zhang X.X., Moon C.D., Gehrig S.M.,
RA Godfrey S.A., Knight C.G., Malone J.G., Robinson Z., Spiers A.J.,
RA Harris S., Challis G.L., Yaxley A.M., Harris D., Seeger K., Murphy L.,
RA Rutter S., Squares R., Quail M.A., Saunders E., Mavromatis K.,
RA Brettin T.S., Bentley S.D., Hothersall J., Stephens E., Thomas C.M.,
RA Parkhill J., Levy S.B., Rainey P.B., Thomson N.R.;
RT "Genomic and genetic analyses of diversity and plant interactions of
RT Pseudomonas fluorescens.";
RL Genome Biol. 10:R51.1-R51.16(2009).
CC -!- FUNCTION: Required for chromosome condensation and partitioning.
CC {ECO:0000256|HAMAP-Rule:MF_01894}.
CC -!- SUBUNIT: Homodimer. {ECO:0000256|HAMAP-Rule:MF_01894}.
CC -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000256|HAMAP-Rule:MF_01894}.
CC -!- DOMAIN: Contains large globular domains required for ATP hydrolysis at
CC each terminus and a third globular domain forming a flexible hinge near
CC the middle of the molecule. These domains are separated by coiled-coil
CC structures. {ECO:0000256|HAMAP-Rule:MF_01894}.
CC -!- SIMILARITY: Belongs to the SMC family. SMC3 subfamily.
CC {ECO:0000256|ARBA:ARBA00005917}.
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DR EMBL; CP000094; ABA73542.1; -; Genomic_DNA.
DR RefSeq; WP_011333270.1; NC_007492.2.
DR AlphaFoldDB; Q3KFB4; -.
DR KEGG; pfo:Pfl01_1799; -.
DR eggNOG; COG1196; Bacteria.
DR HOGENOM; CLU_001042_2_2_6; -.
DR Proteomes; UP000002704; Chromosome.
DR GO; GO:0005694; C:chromosome; IEA:InterPro.
DR GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
DR GO; GO:0005524; F:ATP binding; IEA:UniProtKB-UniRule.
DR GO; GO:0016887; F:ATP hydrolysis activity; IEA:InterPro.
DR GO; GO:0003677; F:DNA binding; IEA:UniProtKB-UniRule.
DR GO; GO:0030261; P:chromosome condensation; IEA:InterPro.
DR GO; GO:0007059; P:chromosome segregation; IEA:UniProtKB-UniRule.
DR GO; GO:0006260; P:DNA replication; IEA:UniProtKB-UniRule.
DR GO; GO:0007062; P:sister chromatid cohesion; IEA:InterPro.
DR CDD; cd03278; ABC_SMC_barmotin; 2.
DR Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 2.
DR HAMAP; MF_01894; Smc_prok; 1.
DR InterPro; IPR027417; P-loop_NTPase.
DR InterPro; IPR003395; RecF/RecN/SMC_N.
DR InterPro; IPR024704; SMC.
DR InterPro; IPR010935; SMC_hinge.
DR InterPro; IPR036277; SMC_hinge_sf.
DR InterPro; IPR011890; SMC_prok.
DR NCBIfam; TIGR02168; SMC_prok_B; 1.
DR PANTHER; PTHR43977; STRUCTURAL MAINTENANCE OF CHROMOSOMES PROTEIN 3; 1.
DR PANTHER; PTHR43977:SF1; STRUCTURAL MAINTENANCE OF CHROMOSOMES PROTEIN 3; 1.
DR Pfam; PF06470; SMC_hinge; 1.
DR Pfam; PF02463; SMC_N; 1.
DR PIRSF; PIRSF005719; SMC; 2.
DR SMART; SM00968; SMC_hinge; 1.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
DR SUPFAM; SSF75553; Smc hinge domain; 1.
PE 3: Inferred from homology;
KW ATP-binding {ECO:0000256|HAMAP-Rule:MF_01894};
KW Coiled coil {ECO:0000256|ARBA:ARBA00023054, ECO:0000256|HAMAP-
KW Rule:MF_01894};
KW Cytoplasm {ECO:0000256|ARBA:ARBA00022490, ECO:0000256|HAMAP-Rule:MF_01894};
KW DNA-binding {ECO:0000256|HAMAP-Rule:MF_01894};
KW Nucleotide-binding {ECO:0000256|HAMAP-Rule:MF_01894}.
FT DOMAIN 520..615
FT /note="SMC hinge"
FT /evidence="ECO:0000259|SMART:SM00968"
FT COILED 170..238
FT /evidence="ECO:0000256|HAMAP-Rule:MF_01894"
FT COILED 300..334
FT /evidence="ECO:0000256|HAMAP-Rule:MF_01894"
FT COILED 398..500
FT /evidence="ECO:0000256|HAMAP-Rule:MF_01894"
FT COILED 656..690
FT /evidence="ECO:0000256|HAMAP-Rule:MF_01894"
FT COILED 768..900
FT /evidence="ECO:0000256|HAMAP-Rule:MF_01894"
FT BINDING 32..39
FT /ligand="ATP"
FT /ligand_id="ChEBI:CHEBI:30616"
FT /evidence="ECO:0000256|HAMAP-Rule:MF_01894"
SQ SEQUENCE 1162 AA; 131326 MW; 40BC26D1B4267637 CRC64;
MRLKCIKLAG FKSFVDPTTV NFPSNMAAVV GPNGCGKSNI IDAVRWVMGE SSAKNLRGES
MTDVIFNGST SRKPVSQASI ELVFDNSDGT LLGEWAAYAE ISIRRKVTRD SQTTYYLNGA
KCRRRDITDI FLGTGLGPRS YSIIEQGMIS KLIESKPEDL RNFIEEAAGI SKYKERRRET
ENRIRRTHEN LARLTDLREE LERQLERLHR QAEAAKKYQE YKAEERQLKA QLSALRWQDL
NDQVSQRESI IGNQEISFEA LVAEQRNADA AIERLRDGHH DLSERFNLVQ GRFYSVGGDI
ARVEQSIQHG QQRLRQLQDD LKEAERARLE TESHLGHDRT LLLTLGEELD QLTPEQEITN
AAAEDAAAAL EDSETVMHGW QEQWDAFNLT AAEPRRQAEV QQSRIQQLET SMERLADRQK
RLSEERALLS ADPEDAAIME LSEQLAESEA TLEDLQTSEA AQVEKLEQLR QELQQALTAQ
QQAQGDLQRL NGRLASLEAL QQAALDPGTG TAEWLKEHNL AERPRLAEGL KVEAGWELAV
ETVLGADLQA VLVDDFDGFD LSGFAQGDLR LLSPGNDGVR VAGSLLDKVE AQVDLSPWLA
QVKPVDSLEQ ALALRGQLAA GQSLISRDGY WVGRHFLRVR RASEAESGML ARGQEIESLH
AEREEREATV EAMEARLQTL RAQQRQQENG REHLRRLLQD EARQQGELKA QLSAGKAKAE
QLNLRRTRLD EELVELAEQR ELEHENIGEA RIQLQEALDA MALDTEQREL LLAQRDSLRE
RLDRVRQEAR QHKDHAHQLA VRLGSLRAQH DSTRQALERL EMQAERLTEK REQLSLNLEE
GEAPLEELRL KLEELLDKRM SVDDELKTAQ IALEDADREL RDAEKRRTQA EQQSQLIRGQ
LEQQRMEWQA LTVRRKALQD QLLEDGYDLH GVLNTLTAEA SERAAEEELE RIAARIQRLG
AINLAAIDEY QQQSERKRYL DAQDADLVEA LETLENVIRK IDKETRNRFK DTFDQINGGL
QALFPKVFGG GRAYLELTGE DLLDTGVTIM AQPPGKKNST IHLLSGGEKA LTALALVFAI
FKLNPAPFCM LDEVDAPLDD ANVGRYARLV KEMSQTVQFI YITHNKIAME MADQLMGVTM
HEPGCSRLVA VDVEEAMAMV DA
//
