ID Q3SR40_NITWN Unreviewed; 566 AA.
AC Q3SR40;
DT 11-OCT-2005, integrated into UniProtKB/TrEMBL.
DT 11-OCT-2005, sequence version 1.
DT 27-MAR-2024, entry version 103.
DE SubName: Full=NADH/Ubiquinone/plastoquinone (Complex I) {ECO:0000313|EMBL:ABA05251.1};
DE EC=1.6.99.5 {ECO:0000313|EMBL:ABA05251.1};
GN OrderedLocusNames=Nwi_1992 {ECO:0000313|EMBL:ABA05251.1};
OS Nitrobacter winogradskyi (strain ATCC 25391 / DSM 10237 / CIP 104748 /
OS NCIMB 11846 / Nb-255).
OC Bacteria; Pseudomonadota; Alphaproteobacteria; Hyphomicrobiales;
OC Nitrobacteraceae; Nitrobacter.
OX NCBI_TaxID=323098 {ECO:0000313|EMBL:ABA05251.1, ECO:0000313|Proteomes:UP000002531};
RN [1] {ECO:0000313|EMBL:ABA05251.1, ECO:0000313|Proteomes:UP000002531}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC 25391 / DSM 10237 / CIP 104748 / NCIMB 11846 / Nb-255
RC {ECO:0000313|Proteomes:UP000002531};
RX PubMed=16517654; DOI=10.1128/AEM.72.3.2050-2063.2006;
RA Starkenburg S.R., Chain P.S., Sayavedra-Soto L.A., Hauser L., Land M.L.,
RA Larimer F.W., Malfatti S.A., Klotz M.G., Bottomley P.J., Arp D.J.,
RA Hickey W.J.;
RT "Genome sequence of the chemolithoautotrophic nitrite-oxidizing bacterium
RT Nitrobacter winogradskyi Nb-255.";
RL Appl. Environ. Microbiol. 72:2050-2063(2006).
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141,
CC ECO:0000256|RuleBase:RU000320}; Multi-pass membrane protein
CC {ECO:0000256|ARBA:ARBA00004141, ECO:0000256|RuleBase:RU000320}.
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DR EMBL; CP000115; ABA05251.1; -; Genomic_DNA.
DR AlphaFoldDB; Q3SR40; -.
DR STRING; 323098.Nwi_1992; -.
DR KEGG; nwi:Nwi_1992; -.
DR eggNOG; COG1009; Bacteria.
DR HOGENOM; CLU_007100_11_0_5; -.
DR Proteomes; UP000002531; Chromosome.
DR GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-KW.
DR GO; GO:0008137; F:NADH dehydrogenase (ubiquinone) activity; IEA:InterPro.
DR GO; GO:0042773; P:ATP synthesis coupled electron transport; IEA:InterPro.
DR InterPro; IPR001750; ND/Mrp_mem.
DR InterPro; IPR003945; NU5C-like.
DR InterPro; IPR001516; Proton_antipo_N.
DR PANTHER; PTHR42829:SF1; INORGANIC CARBON TRANSPORTER SUBUNIT DABB-RELATED; 1.
DR PANTHER; PTHR42829; NADH-UBIQUINONE OXIDOREDUCTASE CHAIN 5; 1.
DR Pfam; PF00361; Proton_antipo_M; 1.
DR Pfam; PF00662; Proton_antipo_N; 1.
DR PRINTS; PR01434; NADHDHGNASE5.
PE 4: Predicted;
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Oxidoreductase {ECO:0000313|EMBL:ABA05251.1};
KW Reference proteome {ECO:0000313|Proteomes:UP000002531};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692,
KW ECO:0000256|RuleBase:RU000320};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}; Transport {ECO:0000256|ARBA:ARBA00022448};
KW Ubiquinone {ECO:0000313|EMBL:ABA05251.1}.
FT TRANSMEM 6..25
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 37..59
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 79..99
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 111..129
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 135..151
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 207..226
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 247..264
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 276..296
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 317..338
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 382..403
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 415..432
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 444..466
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 478..507
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 73..112
FT /note="NADH-Ubiquinone oxidoreductase (complex I) chain 5
FT N-terminal"
FT /evidence="ECO:0000259|Pfam:PF00662"
FT DOMAIN 128..355
FT /note="NADH:quinone oxidoreductase/Mrp antiporter membrane
FT subunit"
FT /evidence="ECO:0000259|Pfam:PF00361"
SQ SEQUENCE 566 AA; 61559 MW; 97BA09F8971A0BE6 CRC64;
MDQWVSWCLV VLPALPVLSA IMAPLAGSGQ QARAARLSVA MTAVTCVVSV ALLVAVLRAP
QGDVTVARLG PAALMLDNLA VAMAVLVSAI SLVVHVYSVR YMADEPGYVR FFAMLDLMTA
VILLMVTAAD LLTLLAAWFL IGVLLFFLLG FDTSRKASGR YALWTFLTYR VGDLPMVGAA
LLLWHGYGTA ELSELFARIT ANPDVQLGGV AVVPLVAMLL ALAAFARSAQ FLLHTWLPYT
MDGPTPVSAL MHAGIVNAGG FLFNRFAPVF VHAPDALHLA FVVGLVTALI GSALMLTQND
VKKSLGYSTM GQMGFMIMEC GLGAFSLAVY HLIAHGLFKA TLFLNAGNVI GDSRREDGVP
PDDIYSFVVE RRPLREVQKV PWLWAALATV LVPALVLGLS HGMVAADFFH KQGSVVLLFF
GWVTGAQLFF SIHKMPSESP LRTLTMVLLS FFIVVVGYTL IAHTFENFLY PDAELRDAIY
AAASINVLAF DTLVVLVTVA LVGSWLATFY THSLEFGGKP GTRWNAIYLN LYALFSREFY
VSYIYTQLAR GTLSATKRVN IWLRWV
//
