ID Q3ZA50_DEHM1 Unreviewed; 277 AA.
AC Q3ZA50;
DT 27-SEP-2005, integrated into UniProtKB/TrEMBL.
DT 27-SEP-2005, sequence version 1.
DT 27-MAR-2024, entry version 89.
DE SubName: Full=Hydrolase, alpha/beta fold family {ECO:0000313|EMBL:AAW40506.1};
GN OrderedLocusNames=DET0149 {ECO:0000313|EMBL:AAW40506.1};
OS Dehalococcoides mccartyi (strain ATCC BAA-2266 / KCTC 15142 / 195)
OS (Dehalococcoides ethenogenes (strain 195)).
OC Bacteria; Chloroflexota; Dehalococcoidia; Dehalococcoidales;
OC Dehalococcoidaceae; Dehalococcoides.
OX NCBI_TaxID=243164 {ECO:0000313|EMBL:AAW40506.1, ECO:0000313|Proteomes:UP000008289};
RN [1] {ECO:0000313|EMBL:AAW40506.1, ECO:0000313|Proteomes:UP000008289}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC BAA-2266 / KCTC 15142 / 195
RC {ECO:0000313|Proteomes:UP000008289};
RX PubMed=15637277; DOI=10.1126/science.1102226;
RA Seshadri R., Adrian L., Fouts D.E., Eisen J.A., Phillippy A.M., Methe B.A.,
RA Ward N.L., Nelson W.C., Deboy R.T., Khouri H.M., Kolonay J.F., Dodson R.J.,
RA Daugherty S.C., Brinkac L.M., Sullivan S.A., Madupu R., Nelson K.E.,
RA Kang K.H., Impraim M., Tran K., Robinson J.M., Forberger H.A., Fraser C.M.,
RA Zinder S.H., Heidelberg J.F.;
RT "Genome sequence of the PCE-dechlorinating bacterium Dehalococcoides
RT ethenogenes.";
RL Science 307:105-108(2005).
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DR EMBL; CP000027; AAW40506.1; -; Genomic_DNA.
DR RefSeq; WP_010935954.1; NC_002936.3.
DR AlphaFoldDB; Q3ZA50; -.
DR STRING; 243164.DET0149; -.
DR ESTHER; dehm1-q3za50; Monoglyceridelipase_lysophospholip.
DR KEGG; det:DET0149; -.
DR PATRIC; fig|243164.10.peg.140; -.
DR eggNOG; COG2267; Bacteria.
DR HOGENOM; CLU_026209_7_2_0; -.
DR InParanoid; Q3ZA50; -.
DR Proteomes; UP000008289; Chromosome.
DR GO; GO:0052689; F:carboxylic ester hydrolase activity; IEA:InterPro.
DR Gene3D; 3.40.50.1820; alpha/beta hydrolase; 1.
DR InterPro; IPR029058; AB_hydrolase.
DR InterPro; IPR000073; AB_hydrolase_1.
DR InterPro; IPR012354; Esterase_lipase.
DR InterPro; IPR022742; Hydrolase_4.
DR PANTHER; PTHR11614:SF87; MONOGLYCERIDE LIPASE; 1.
DR PANTHER; PTHR11614; PHOSPHOLIPASE-RELATED; 1.
DR Pfam; PF12146; Hydrolase_4; 1.
DR PIRSF; PIRSF017388; Esterase_lipase; 1.
DR PRINTS; PR00111; ABHYDROLASE.
DR SUPFAM; SSF53474; alpha/beta-Hydrolases; 1.
PE 4: Predicted;
KW Hydrolase {ECO:0000313|EMBL:AAW40506.1}.
FT DOMAIN 26..261
FT /note="Serine aminopeptidase S33"
FT /evidence="ECO:0000259|Pfam:PF12146"
FT ACT_SITE 108
FT /note="Nucleophile"
FT /evidence="ECO:0000256|PIRSR:PIRSR017388-1"
FT ACT_SITE 224
FT /note="Charge relay system"
FT /evidence="ECO:0000256|PIRSR:PIRSR017388-1"
FT ACT_SITE 254
FT /note="Charge relay system"
FT /evidence="ECO:0000256|PIRSR:PIRSR017388-1"
FT SITE 155
FT /note="Important for substrate specificity"
FT /evidence="ECO:0000256|PIRSR:PIRSR017388-3"
SQ SEQUENCE 277 AA; 31071 MW; ED3565631ADEA513 CRC64;
MRFTEGHFKG CQDYNCYYQA LLPNGSPKAI VLVVHGLGEH SGRYSELAHY LADRSYAVYA
YDHFGHGKTD GKAGYVSSYD VYIYDLISAF SMVQAKHPTS KIFIFGHSMG GLVTAAYASK
HQYDASGLIF SSIALKPYTG MPGILNQLVK PISKIAPMLG IRKIDAATIS HNKEIVKAYD
EDPLVLHQRM SAQMAAEFLR ICQDLPDFLK NISLPSLIIH GEEDHLVSIS GSRELVQKIS
SKDKTLITYP GMYHEVFNEP DCPQVWNDLF FWLENHL
//
