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Database: UniProt
Entry: Q41382
LinkDB: Q41382
Original site: Q41382 
ID   RH7_SPIOL               Reviewed;         685 AA.
AC   Q41382;
DT   30-MAY-2006, integrated into UniProtKB/Swiss-Prot.
DT   01-NOV-1996, sequence version 1.
DT   18-SEP-2019, entry version 84.
DE   RecName: Full=DEAD-box ATP-dependent RNA helicase 7;
DE            EC=3.6.4.13;
GN   Name=RH7; Synonyms=PRH75;
OS   Spinacia oleracea (Spinach).
OC   Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC   Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae;
OC   Pentapetalae; Caryophyllales; Chenopodiaceae; Chenopodioideae;
OC   Anserineae; Spinacia.
OX   NCBI_TaxID=3562;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [MRNA], DEVELOPMENTAL STAGE, AND SUBCELLULAR
RP   LOCATION.
RC   TISSUE=Seedling;
RX   PubMed=9121476; DOI=10.1128/mcb.17.4.2257;
RA   Lorkovic Z.J., Herrmann R.G., Oelmueller R.;
RT   "PRH 75, a new nuclear-localized member of the DEAD-box protein family
RT   from higher plants.";
RL   Mol. Cell. Biol. 17:2257-2265(1997).
CC   -!- CATALYTIC ACTIVITY:
CC       Reaction=ATP + H2O = ADP + H(+) + phosphate; Xref=Rhea:RHEA:13065,
CC         ChEBI:CHEBI:15377, ChEBI:CHEBI:15378, ChEBI:CHEBI:30616,
CC         ChEBI:CHEBI:43474, ChEBI:CHEBI:456216; EC=3.6.4.13;
CC   -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000269|PubMed:9121476}.
CC   -!- DEVELOPMENTAL STAGE: Mainly expressed in young and rapidly
CC       developing tissues. {ECO:0000269|PubMed:9121476}.
CC   -!- DOMAIN: The Q motif is unique to and characteristic of the DEAD
CC       box family of RNA helicases and controls ATP binding and
CC       hydrolysis.
CC   -!- SIMILARITY: Belongs to the DEAD box helicase family. DDX21/DDX50
CC       subfamily. {ECO:0000305}.
DR   EMBL; X99937; CAA68193.1; -; mRNA.
DR   PIR; T09159; T09159.
DR   SMR; Q41382; -.
DR   PRIDE; Q41382; -.
DR   GO; GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR   GO; GO:0003723; F:RNA binding; IEA:UniProtKB-KW.
DR   GO; GO:0003724; F:RNA helicase activity; IEA:UniProtKB-EC.
DR   InterPro; IPR011545; DEAD/DEAH_box_helicase_dom.
DR   InterPro; IPR012562; GUCT.
DR   InterPro; IPR014001; Helicase_ATP-bd.
DR   InterPro; IPR001650; Helicase_C.
DR   InterPro; IPR027417; P-loop_NTPase.
DR   InterPro; IPR035979; RBD_domain_sf.
DR   InterPro; IPR000629; RNA-helicase_DEAD-box_CS.
DR   InterPro; IPR014014; RNA_helicase_DEAD_Q_motif.
DR   Pfam; PF00270; DEAD; 1.
DR   Pfam; PF08152; GUCT; 1.
DR   Pfam; PF00271; Helicase_C; 1.
DR   SMART; SM00487; DEXDc; 1.
DR   SMART; SM00490; HELICc; 1.
DR   SUPFAM; SSF52540; SSF52540; 2.
DR   SUPFAM; SSF54928; SSF54928; 1.
DR   PROSITE; PS00039; DEAD_ATP_HELICASE; 1.
DR   PROSITE; PS51192; HELICASE_ATP_BIND_1; 1.
DR   PROSITE; PS51194; HELICASE_CTER; 1.
DR   PROSITE; PS51195; Q_MOTIF; 1.
PE   2: Evidence at transcript level;
KW   ATP-binding; Helicase; Hydrolase; Nucleotide-binding; Nucleus;
KW   RNA-binding.
FT   CHAIN         1    685       DEAD-box ATP-dependent RNA helicase 7.
FT                                /FTId=PRO_0000239149.
FT   DOMAIN      138    320       Helicase ATP-binding.
FT                                {ECO:0000255|PROSITE-ProRule:PRU00541}.
FT   DOMAIN      349    491       Helicase C-terminal.
FT                                {ECO:0000255|PROSITE-ProRule:PRU00542}.
FT   NP_BIND     151    158       ATP. {ECO:0000255|PROSITE-
FT                                ProRule:PRU00541}.
FT   MOTIF       107    135       Q motif.
FT   MOTIF       266    269       DEAD box.
FT   COMPBIAS     17     94       Lys-rich.
FT   COMPBIAS    646    683       Gly-rich.
SQ   SEQUENCE   685 AA;  73085 MW;  F7717C666CBF87F7 CRC64;
     MPSISMMSDA ITPETLKKEK KMKSETLDSD DTVVKKEKSS SKKKEKSSSS GKKDKEEKEK
     KKKRKAVDLD DSSDKSDNSS ELVQADDLKP KKAKVMEEAV VEAEDPNSLS NFRISKPLKD
     VLISKGIKAL FPIQAMTFDN VIDGCDLVGR ARTGQGKTLA FVLPIVESLV NGRTKDLRRS
     GHGRLPSVLV LLPTRELATQ VLADFQVYGG AVGLTACSVY GGAPFHSQIS SLTRGVDIVV
     GTPGRVKDLL EKGVLKLGSL LFRVLDEADE MLKMGFVDDV ELILGKVDHV SKVQTLLFSA
     TLPSWVKQIS TRFLKSAKKT VDLVSDQKMK ASISVRHIVI PCSASARPDL IPDIIRCYGS
     GGRSIIFTET KESASQLAGL LTGARPLHGD IQQTQREVTL KGFRTGKFMT LVATNVAARG
     LDINDVQLII QCEPPRDVED YIHRSGRTGR AGNTGVAVML YDPKRSSVTK IERESGVKFE
     HLSAPQPVDV AKAVGIEAAA AILQISDSVI PAFKDAAEEL LSTSGLSAVD ILSKALAKAA
     GYSDIKERSL LTGMEGYVTL LLDAGRPFYG QSFAYTVLKR FLPATKADSI MGVALTADKS
     GAVFDVPVDD LETFLVGAEN AAGVNLDVVK ALPPLEEKVQ ISRRFGGGGR GGRGGGYGGR
     GGGYGGGGYG GGGGYGGRGG GYGRR
//
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