ID ZFP1_ARATH Reviewed; 228 AA.
AC Q42485;
DT 27-JAN-2003, integrated into UniProtKB/Swiss-Prot.
DT 01-NOV-1996, sequence version 1.
DT 24-JAN-2024, entry version 145.
DE RecName: Full=Zinc finger protein 1 {ECO:0000305};
DE Short=AtZFP1 {ECO:0000303|PubMed:8980531};
GN Name=ZFP1 {ECO:0000303|PubMed:7599312}; OrderedLocusNames=At1g80730;
GN ORFNames=F23A5.8;
OS Arabidopsis thaliana (Mouse-ear cress).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis.
OX NCBI_TaxID=3702;
RN [1]
RP NUCLEOTIDE SEQUENCE [MRNA].
RC STRAIN=cv. Landsberg erecta; TISSUE=Root;
RX PubMed=7599312; DOI=10.1007/bf00020246;
RA Tague B.W., Goodman H.M.;
RT "Characterization of a family of Arabidopsis zinc finger protein cDNAs.";
RL Plant Mol. Biol. 28:267-279(1995).
RN [2]
RP NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RC STRAIN=cv. Columbia;
RA Goodman H.M., Gallant P., Keifer-Higgins S., Rubenfield M., Church G.M.;
RT "A 37.5 Kb sequence from Arabidopsis thaliana chromosome I.";
RL Submitted (MAY-1996) to the EMBL/GenBank/DDBJ databases.
RN [3]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. Columbia;
RX PubMed=11130712; DOI=10.1038/35048500;
RA Theologis A., Ecker J.R., Palm C.J., Federspiel N.A., Kaul S., White O.,
RA Alonso J., Altafi H., Araujo R., Bowman C.L., Brooks S.Y., Buehler E.,
RA Chan A., Chao Q., Chen H., Cheuk R.F., Chin C.W., Chung M.K., Conn L.,
RA Conway A.B., Conway A.R., Creasy T.H., Dewar K., Dunn P., Etgu P.,
RA Feldblyum T.V., Feng J.-D., Fong B., Fujii C.Y., Gill J.E., Goldsmith A.D.,
RA Haas B., Hansen N.F., Hughes B., Huizar L., Hunter J.L., Jenkins J.,
RA Johnson-Hopson C., Khan S., Khaykin E., Kim C.J., Koo H.L.,
RA Kremenetskaia I., Kurtz D.B., Kwan A., Lam B., Langin-Hooper S., Lee A.,
RA Lee J.M., Lenz C.A., Li J.H., Li Y.-P., Lin X., Liu S.X., Liu Z.A.,
RA Luros J.S., Maiti R., Marziali A., Militscher J., Miranda M., Nguyen M.,
RA Nierman W.C., Osborne B.I., Pai G., Peterson J., Pham P.K., Rizzo M.,
RA Rooney T., Rowley D., Sakano H., Salzberg S.L., Schwartz J.R., Shinn P.,
RA Southwick A.M., Sun H., Tallon L.J., Tambunga G., Toriumi M.J., Town C.D.,
RA Utterback T., Van Aken S., Vaysberg M., Vysotskaia V.S., Walker M., Wu D.,
RA Yu G., Fraser C.M., Venter J.C., Davis R.W.;
RT "Sequence and analysis of chromosome 1 of the plant Arabidopsis thaliana.";
RL Nature 408:816-820(2000).
RN [4]
RP GENOME REANNOTATION.
RC STRAIN=cv. Columbia;
RX PubMed=27862469; DOI=10.1111/tpj.13415;
RA Cheng C.Y., Krishnakumar V., Chan A.P., Thibaud-Nissen F., Schobel S.,
RA Town C.D.;
RT "Araport11: a complete reannotation of the Arabidopsis thaliana reference
RT genome.";
RL Plant J. 89:789-804(2017).
RN [5]
RP FUNCTION, AND TISSUE SPECIFICITY.
RX PubMed=8980531; DOI=10.1007/bf00020477;
RA Tague B.W., Gallant P., Goodman H.M.;
RT "Expression analysis of an Arabidopsis C2H2 zinc finger protein gene.";
RL Plant Mol. Biol. 32:785-796(1996).
RN [6]
RP TISSUE SPECIFICITY, AND INDUCTION BY LIGHT.
RX PubMed=10794528; DOI=10.1023/a:1006352809700;
RA Chrispeels H.E., Oettinger H., Janvier N., Tague B.W.;
RT "AtZFP1, encoding Arabidopsis thaliana C2H2 zinc-finger protein 1, is
RT expressed downstream of photomorphogenic activation.";
RL Plant Mol. Biol. 42:279-290(2000).
RN [7]
RP FUNCTION.
RX PubMed=24808098; DOI=10.1104/pp.113.234294;
RA Joseph M.P., Papdi C., Kozma-Bognar L., Nagy I., Lopez-Carbonell M.,
RA Rigo G., Koncz C., Szabados L.;
RT "The Arabidopsis ZINC FINGER PROTEIN3 interferes with abscisic acid and
RT light signaling in seed germination and plant development.";
RL Plant Physiol. 165:1203-1220(2014).
CC -!- FUNCTION: May play a role in the regulation of shoot development,
CC downstream of photomorphogenic activation (Probable). Acts as a
CC negative regulator of abscisic acid (ABA) signaling during germination
CC and early seedling development (PubMed:24808098).
CC {ECO:0000269|PubMed:24808098, ECO:0000305|PubMed:8980531}.
CC -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000250|UniProtKB:Q39261}.
CC -!- TISSUE SPECIFICITY: Highly expressed in the shoot apex, including the
CC apical meristem, developing leaves and developing vascular system.
CC {ECO:0000269|PubMed:10794528, ECO:0000305|PubMed:8980531}.
CC -!- INDUCTION: Induced by white light in dark-grown seedlings.
CC {ECO:0000269|PubMed:10794528}.
CC -!- MISCELLANEOUS: Seeds over-expressing ZFP1 are insensitive to inhibition
CC of germination by abscisic acid (ABA). {ECO:0000269|PubMed:24808098}.
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DR EMBL; L39644; AAA87297.1; -; mRNA.
DR EMBL; U53501; AAA98913.1; -; Genomic_DNA.
DR EMBL; AC011713; AAF14661.1; -; Genomic_DNA.
DR EMBL; CP002684; AEE36441.1; -; Genomic_DNA.
DR PIR; S55881; S55881.
DR RefSeq; NP_178188.1; NM_106721.2.
DR AlphaFoldDB; Q42485; -.
DR SMR; Q42485; -.
DR BioGRID; 29630; 2.
DR IntAct; Q42485; 2.
DR STRING; 3702.Q42485; -.
DR PaxDb; 3702-AT1G80730-1; -.
DR EnsemblPlants; AT1G80730.1; AT1G80730.1; AT1G80730.
DR GeneID; 844412; -.
DR Gramene; AT1G80730.1; AT1G80730.1; AT1G80730.
DR KEGG; ath:AT1G80730; -.
DR Araport; AT1G80730; -.
DR TAIR; AT1G80730; ZFP1.
DR eggNOG; ENOG502QTKZ; Eukaryota.
DR HOGENOM; CLU_1226321_0_0_1; -.
DR InParanoid; Q42485; -.
DR OMA; QVFKHTI; -.
DR OrthoDB; 731213at2759; -.
DR PhylomeDB; Q42485; -.
DR PRO; PR:Q42485; -.
DR Proteomes; UP000006548; Chromosome 1.
DR ExpressionAtlas; Q42485; baseline and differential.
DR Genevisible; Q42485; AT.
DR GO; GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
DR GO; GO:0003700; F:DNA-binding transcription factor activity; ISS:TAIR.
DR GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR GO; GO:0009738; P:abscisic acid-activated signaling pathway; IEA:UniProtKB-KW.
DR GO; GO:0009788; P:negative regulation of abscisic acid-activated signaling pathway; IMP:UniProtKB.
DR GO; GO:0009640; P:photomorphogenesis; IEP:TAIR.
DR Gene3D; 3.30.160.60; Classic Zinc Finger; 1.
DR InterPro; IPR044246; ZFP3-like.
DR InterPro; IPR036236; Znf_C2H2_sf.
DR InterPro; IPR013087; Znf_C2H2_type.
DR PANTHER; PTHR47287; C2H2 AND C2HC ZINC FINGERS SUPERFAMILY PROTEIN; 1.
DR PANTHER; PTHR47287:SF1; C2H2-TYPE DOMAIN-CONTAINING PROTEIN; 1.
DR SUPFAM; SSF57667; beta-beta-alpha zinc fingers; 1.
DR PROSITE; PS00028; ZINC_FINGER_C2H2_1; 1.
DR PROSITE; PS50157; ZINC_FINGER_C2H2_2; 1.
PE 2: Evidence at transcript level;
KW Abscisic acid signaling pathway; Metal-binding; Nucleus;
KW Reference proteome; Zinc; Zinc-finger.
FT CHAIN 1..228
FT /note="Zinc finger protein 1"
FT /id="PRO_0000047842"
FT ZN_FING 68..90
FT /note="C2H2-type"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00042"
SQ SEQUENCE 228 AA; 25468 MW; ED1EB94CCA94B95E CRC64;
MEPSIKGDQE MLKIKKQGHQ DLELGLTLLS RGTATSSELN LIDSFKTSSS STSHHQHQQE
QLADPRVFSC NYCQRKFYSS QALGGHQNAH KRERTLAKRG QYYKMTLSSL PSSAFAFGHG
SVSRFASMAS LPLHGSVNNR STLGIQAHST IHKPSFLGRQ TTSLSHVFKQ SIHQKPTIGK
MLPEKFHLEV AGNNNSNMVA AKLERIGHFK SNQEDHNQFK KIDLTLKL
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