ID BMPA_BORBU Reviewed; 339 AA.
AC Q45010; P94249; Q44857;
DT 15-DEC-1998, integrated into UniProtKB/Swiss-Prot.
DT 01-NOV-1996, sequence version 1.
DT 27-MAR-2024, entry version 121.
DE RecName: Full=Basic membrane protein A;
DE AltName: Full=Immunodominant antigen P39;
DE Flags: Precursor;
GN Name=bmpA; OrderedLocusNames=BB_0383;
OS Borreliella burgdorferi (strain ATCC 35210 / DSM 4680 / CIP 102532 / B31)
OS (Borrelia burgdorferi).
OC Bacteria; Spirochaetota; Spirochaetia; Spirochaetales; Borreliaceae;
OC Borreliella.
OX NCBI_TaxID=224326;
RN [1]
RP NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RC STRAIN=Sh-2-82;
RX PubMed=8050720; DOI=10.1111/j.1574-6968.1994.tb06917.x;
RA Simpson W.J., Cieplak W., Schrumpf M.E., Barbour A.G., Schwan T.G.;
RT "Nucleotide sequence and analysis of the gene in Borrelia burgdorferi
RT encoding the immunogenic P39 antigen.";
RL FEMS Microbiol. Lett. 119:381-388(1994).
RN [2]
RP NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RC STRAIN=ATCC 53899 / 297;
RX PubMed=8978084; DOI=10.1111/j.1574-6968.1996.tb08594.x;
RA Aron L., Toth C., Godfrey H.P., Cabello F.C.;
RT "Identification and mapping of a chromosomal gene cluster of Borrelia
RT burgdorferi containing genes expressed in vivo.";
RL FEMS Microbiol. Lett. 145:309-314(1996).
RN [3]
RP NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RC STRAIN=BL206;
RA Orlova T., Bugrysheva J., Novikova S., Godfrey H.P., Cabello F.C.;
RL Submitted (JUL-2001) to the EMBL/GenBank/DDBJ databases.
RN [4]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC 35210 / DSM 4680 / CIP 102532 / B31;
RX PubMed=9403685; DOI=10.1038/37551;
RA Fraser C.M., Casjens S., Huang W.M., Sutton G.G., Clayton R.A.,
RA Lathigra R., White O., Ketchum K.A., Dodson R.J., Hickey E.K., Gwinn M.L.,
RA Dougherty B.A., Tomb J.-F., Fleischmann R.D., Richardson D.L.,
RA Peterson J.D., Kerlavage A.R., Quackenbush J., Salzberg S.L., Hanson M.,
RA van Vugt R., Palmer N., Adams M.D., Gocayne J.D., Weidman J.F.,
RA Utterback T.R., Watthey L., McDonald L.A., Artiach P., Bowman C.,
RA Garland S.A., Fujii C., Cotton M.D., Horst K., Roberts K.M., Hatch B.,
RA Smith H.O., Venter J.C.;
RT "Genomic sequence of a Lyme disease spirochaete, Borrelia burgdorferi.";
RL Nature 390:580-586(1997).
RN [5]
RP NUCLEOTIDE SEQUENCE [GENOMIC DNA] OF 248-339.
RC STRAIN=212;
RX PubMed=7812434; DOI=10.1099/13500872-140-11-2931;
RA Ojaimi C., Davidson B.E., Saint-Girons I., Old I.G.;
RT "Conservation of gene arrangement and an unusual organization of rRNA genes
RT in the linear chromosomes of the Lyme disease spirochaetes Borrelia
RT burgdorferi, B. garinii and B. afzelii.";
RL Microbiology 140:2931-2940(1994).
CC -!- FUNCTION: Not known; immunogenic protein.
CC -!- SUBCELLULAR LOCATION: Cell membrane {ECO:0000305}; Lipid-anchor
CC {ECO:0000305}.
CC -!- SIMILARITY: Belongs to the BMP lipoprotein family. {ECO:0000305}.
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DR EMBL; L24194; AAA72406.1; -; Genomic_DNA.
DR EMBL; U49938; AAC44712.1; -; Genomic_DNA.
DR EMBL; AF400111; AAM89914.1; -; Genomic_DNA.
DR EMBL; AE000783; AAC66757.1; -; Genomic_DNA.
DR EMBL; L35050; AAC41401.1; -; Genomic_DNA.
DR PIR; F70147; F70147.
DR RefSeq; NP_212517.1; NC_001318.1.
DR RefSeq; WP_002656850.1; NC_001318.1.
DR AlphaFoldDB; Q45010; -.
DR SMR; Q45010; -.
DR STRING; 224326.BB_0383; -.
DR PaxDb; 224326-BB_0383; -.
DR EnsemblBacteria; AAC66757; AAC66757; BB_0383.
DR KEGG; bbu:BB_0383; -.
DR PATRIC; fig|224326.49.peg.778; -.
DR HOGENOM; CLU_038813_0_2_12; -.
DR OrthoDB; 9769871at2; -.
DR Proteomes; UP000001807; Chromosome.
DR GO; GO:0016020; C:membrane; IDA:CAFA.
DR GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
DR CDD; cd06354; PBP1_PrnA-like; 1.
DR Gene3D; 3.40.50.2300; -; 2.
DR InterPro; IPR028082; Peripla_BP_I.
DR InterPro; IPR003760; PnrA-like.
DR PANTHER; PTHR34296:SF2; ABC TRANSPORTER GUANOSINE-BINDING PROTEIN NUPN; 1.
DR PANTHER; PTHR34296; TRANSCRIPTIONAL ACTIVATOR PROTEIN MED; 1.
DR Pfam; PF02608; Bmp; 1.
DR SUPFAM; SSF53822; Periplasmic binding protein-like I; 1.
PE 3: Inferred from homology;
KW Cell membrane; Lipoprotein; Membrane; Palmitate; Reference proteome;
KW Signal.
FT SIGNAL 1..17
FT /evidence="ECO:0000305"
FT CHAIN 18..339
FT /note="Basic membrane protein A"
FT /id="PRO_0000017996"
FT LIPID 18
FT /note="N-palmitoyl cysteine"
FT /evidence="ECO:0000305"
FT LIPID 18
FT /note="S-diacylglycerol cysteine"
FT /evidence="ECO:0000305"
FT VARIANT 278
FT /note="F -> S (in strain: 297)"
SQ SEQUENCE 339 AA; 36968 MW; A9581868CA7DB923 CRC64;
MNKILLLILL ESIVFLSCSG KGSLGSEIPK VSLIIDGTFD DKSFNESALN GVKKVKEEFK
IELVLKESSS NSYLSDLEGL KDAGSDLIWL IGYRFSDVAK VAALQNPDMK YAIIDPIYSN
DPIPANLVGM TFRAQEGAFL TGYIAAKLSK TGKIGFLGGI EGEIVDAFRY GYEAGAKYAN
KDIKISTQYI GSFADLEAGR SVATRMYSDE IDIIHHAAGL GGIGAIEVAK ELGSGHYIIG
VDEDQAYLAP DNVITSTTKD VGRALNIFTS NHLKTNTFEG GKLINYGLKE GVVGFVRNPK
MISFELEKEI DNLSSKIINK EIIVPSNKES YEKFLKEFI
//
