ID   Q465Z5_METBF            Unreviewed;       448 AA.
AC   Q465Z5;
DT   13-SEP-2005, integrated into UniProtKB/TrEMBL.
DT   13-SEP-2005, sequence version 1.
DT   27-MAR-2024, entry version 92.
DE   SubName: Full=Trk system potassium uptake protein {ECO:0000313|EMBL:AAZ72297.1};
GN   OrderedLocusNames=Mbar_A3424 {ECO:0000313|EMBL:AAZ72297.1};
OS   Methanosarcina barkeri (strain Fusaro / DSM 804).
OC   Archaea; Euryarchaeota; Stenosarchaea group; Methanomicrobia;
OC   Methanosarcinales; Methanosarcinaceae; Methanosarcina.
OX   NCBI_TaxID=269797 {ECO:0000313|EMBL:AAZ72297.1};
RN   [1] {ECO:0000313|EMBL:AAZ72297.1}
RP   NUCLEOTIDE SEQUENCE.
RC   STRAIN=Fusaro {ECO:0000313|EMBL:AAZ72297.1};
RA   Copeland A., Lucas S., Lapidus A., Barry K., Detter J.C., Glavina T.,
RA   Hammon N., Israni S., Pitluck S., Goodwin L.A., Saunders E.H., Schmutz J.,
RA   Larimer F., Land M., Anderson I., Richardson P.;
RT   "Complete sequence of chromosome 1 of Methanosarcina barkeri str. fusaro.";
RL   Submitted (JUN-2006) to the EMBL/GenBank/DDBJ databases.
CC   -!- FUNCTION: Part of a potassium transport system.
CC       {ECO:0000256|ARBA:ARBA00003660}.
CC   ---------------------------------------------------------------------------
CC   Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC   Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC   ---------------------------------------------------------------------------
DR   EMBL; CP000099; AAZ72297.1; -; Genomic_DNA.
DR   AlphaFoldDB; Q465Z5; -.
DR   STRING; 269797.Mbar_A3424; -.
DR   PaxDb; 269797-Mbar_A3424; -.
DR   KEGG; mba:Mbar_A3424; -.
DR   eggNOG; arCOG01959; Archaea.
DR   HOGENOM; CLU_046525_0_0_2; -.
DR   OrthoDB; 27588at2157; -.
DR   GO; GO:0005886; C:plasma membrane; IEA:InterPro.
DR   GO; GO:0015079; F:potassium ion transmembrane transporter activity; IEA:InterPro.
DR   Gene3D; 3.40.50.720; NAD(P)-binding Rossmann-like Domain; 2.
DR   Gene3D; 3.30.70.1450; Regulator of K+ conductance, C-terminal domain; 2.
DR   InterPro; IPR006036; K_uptake_TrkA.
DR   InterPro; IPR036291; NAD(P)-bd_dom_sf.
DR   InterPro; IPR006037; RCK_C.
DR   InterPro; IPR036721; RCK_C_sf.
DR   InterPro; IPR003148; RCK_N.
DR   PANTHER; PTHR43833; POTASSIUM CHANNEL PROTEIN 2-RELATED-RELATED; 1.
DR   PANTHER; PTHR43833:SF5; TRK SYSTEM POTASSIUM UPTAKE PROTEIN TRKA; 1.
DR   Pfam; PF02080; TrkA_C; 2.
DR   Pfam; PF02254; TrkA_N; 2.
DR   PRINTS; PR00335; KUPTAKETRKA.
DR   SUPFAM; SSF51735; NAD(P)-binding Rossmann-fold domains; 2.
DR   SUPFAM; SSF116726; TrkA C-terminal domain-like; 2.
DR   PROSITE; PS51202; RCK_C; 2.
DR   PROSITE; PS51201; RCK_N; 2.
PE   4: Predicted;
KW   NAD {ECO:0000256|ARBA:ARBA00023027}.
FT   DOMAIN          2..132
FT                   /note="RCK N-terminal"
FT                   /evidence="ECO:0000259|PROSITE:PS51201"
FT   DOMAIN          144..225
FT                   /note="RCK C-terminal"
FT                   /evidence="ECO:0000259|PROSITE:PS51202"
FT   DOMAIN          232..354
FT                   /note="RCK N-terminal"
FT                   /evidence="ECO:0000259|PROSITE:PS51201"
FT   DOMAIN          368..448
FT                   /note="RCK C-terminal"
FT                   /evidence="ECO:0000259|PROSITE:PS51202"
SQ   SEQUENCE   448 AA;  49026 MW;  5ADA25D1128FC463 CRC64;
     MKAIVIGAGE VGYHIAKFLS ATHDVIVVEK KEEVARKADE LDVQVLEGNG ANADILANII
     HDADILVAVT GIDEVNIVAC MTAKLIIRSH SGWKETKTIA RVSNPDYIDV PVTSRSQVGV
     DIMICPELAL ASEVAEVLSS PSAIDTEVFA GGKVQMMEFA IRPDSKLIGK QIQDLKLDDS
     CIVSAIFRKQ EIVIPHGDDV IDANDHMVVV GKPRALEELG RVFGNVEPHR NRILLIGCGI
     VGFYLAELID KDENADLKII EYKKSRCIEV AEVLENALIL NGDGTDVNLL REENIEDMDV
     VLAVTDNDEK NLLCSLLAKQ MGAKKVIARA DRPDYVPLFE MIGIDMAVSP REATVNEVLK
     LTMGKGIEKL TMLEGEKAEI IEYTTSRYSK IIGKSLEKVK FPKDAIVTTV VHNDDIIIPR
     GDSVIREGDQ VIVFALSSAV SAVEKFFK
//