ID Q46HW0_PROMT Unreviewed; 111 AA.
AC Q46HW0;
DT 13-SEP-2005, integrated into UniProtKB/TrEMBL.
DT 13-SEP-2005, sequence version 1.
DT 27-MAR-2024, entry version 82.
DE SubName: Full=HIT family hydrolase {ECO:0000313|EMBL:AAZ58918.1};
GN OrderedLocusNames=PMN2A_1430 {ECO:0000313|EMBL:AAZ58918.1};
OS Prochlorococcus marinus (strain NATL2A).
OC Bacteria; Cyanobacteriota; Cyanophyceae; Synechococcales;
OC Prochlorococcaceae; Prochlorococcus.
OX NCBI_TaxID=59920 {ECO:0000313|EMBL:AAZ58918.1, ECO:0000313|Proteomes:UP000002535};
RN [1] {ECO:0000313|EMBL:AAZ58918.1, ECO:0000313|Proteomes:UP000002535}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=NATL2A {ECO:0000313|EMBL:AAZ58918.1,
RC ECO:0000313|Proteomes:UP000002535};
RX PubMed=18159947; DOI=10.1371/journal.pgen.0030231;
RA Kettler G.C., Martiny A.C., Huang K., Zucker J., Coleman M.L., Rodrigue S.,
RA Chen F., Lapidus A., Ferriera S., Johnson J., Steglich C., Church G.M.,
RA Richardson P., Chisholm S.W.;
RT "Patterns and implications of gene gain and loss in the evolution of
RT Prochlorococcus.";
RL PLoS Genet. 3:2515-2528(2007).
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DR EMBL; CP000095; AAZ58918.1; -; Genomic_DNA.
DR RefSeq; WP_011294062.1; NC_007335.2.
DR AlphaFoldDB; Q46HW0; -.
DR STRING; 59920.PMN2A_1430; -.
DR KEGG; pmn:PMN2A_1430; -.
DR HOGENOM; CLU_056776_8_1_3; -.
DR OrthoDB; 9784774at2; -.
DR PhylomeDB; Q46HW0; -.
DR Proteomes; UP000002535; Chromosome.
DR GO; GO:0016787; F:hydrolase activity; IEA:UniProtKB-KW.
DR CDD; cd01276; PKCI_related; 1.
DR Gene3D; 3.30.428.10; HIT-like; 1.
DR InterPro; IPR019808; Histidine_triad_CS.
DR InterPro; IPR001310; Histidine_triad_HIT.
DR InterPro; IPR011146; HIT-like.
DR InterPro; IPR036265; HIT-like_sf.
DR PANTHER; PTHR23089:SF33; ADENOSINE 5'-MONOPHOSPHORAMIDASE HINT1; 1.
DR PANTHER; PTHR23089; HISTIDINE TRIAD HIT PROTEIN; 1.
DR Pfam; PF01230; HIT; 1.
DR PRINTS; PR00332; HISTRIAD.
DR SUPFAM; SSF54197; HIT-like; 1.
DR PROSITE; PS00892; HIT_1; 1.
DR PROSITE; PS51084; HIT_2; 1.
PE 4: Predicted;
KW Hydrolase {ECO:0000313|EMBL:AAZ58918.1};
KW Reference proteome {ECO:0000313|Proteomes:UP000002535}.
FT DOMAIN 4..111
FT /note="HIT"
FT /evidence="ECO:0000259|PROSITE:PS51084"
FT MOTIF 95..99
FT /note="Histidine triad motif"
FT /evidence="ECO:0000256|PIRSR:PIRSR601310-3,
FT ECO:0000256|PROSITE-ProRule:PRU00464"
FT ACT_SITE 97
FT /note="Tele-AMP-histidine intermediate"
FT /evidence="ECO:0000256|PIRSR:PIRSR601310-1"
SQ SEQUENCE 111 AA; 12289 MW; 7B08734D535CBCEB CRC64;
MTTIFDKILS GEIPCDEVFS DNKCLAFKDI TPQAPTHILI IPRKPIPSLQ DIKKEDQELL
GHLLLKGTEI ANAAGLESWR TIINTGEEAG QTVFHLHIHI IGGRKLSWPP G
//
