ID Q47DA6_DECAR Unreviewed; 426 AA.
AC Q47DA6;
DT 13-SEP-2005, integrated into UniProtKB/TrEMBL.
DT 13-SEP-2005, sequence version 1.
DT 27-MAR-2024, entry version 93.
DE SubName: Full=UDP-glucose/GDP-mannose dehydrogenase:6-phosphogluconate dehydrogenase, NAD-binding protein {ECO:0000313|EMBL:AAZ47175.1};
GN OrderedLocusNames=Daro_2440 {ECO:0000313|EMBL:AAZ47175.1};
OS Dechloromonas aromatica (strain RCB).
OC Bacteria; Pseudomonadota; Betaproteobacteria; Rhodocyclales; Azonexaceae;
OC Dechloromonas.
OX NCBI_TaxID=159087 {ECO:0000313|EMBL:AAZ47175.1};
RN [1] {ECO:0000313|EMBL:AAZ47175.1}
RP NUCLEOTIDE SEQUENCE.
RC STRAIN=RCB {ECO:0000313|EMBL:AAZ47175.1};
RA Salinero K.K., Copeland A., Lucas S., Lapidus A., Barry K., Detter J.C.,
RA Glavina T., Hammon N., Israni S., Pitluck S., Di Bartolo G., Trong S.,
RA Schmutz J., Larimer F., Land M., Ivanova N., Richardson P.;
RT "Complete sequence of Dechloromonas aromatica RCB.";
RL Submitted (AUG-2005) to the EMBL/GenBank/DDBJ databases.
CC -!- SIMILARITY: Belongs to the UDP-glucose/GDP-mannose dehydrogenase
CC family. {ECO:0000256|PIRNR:PIRNR000124}.
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DR EMBL; CP000089; AAZ47175.1; -; Genomic_DNA.
DR AlphaFoldDB; Q47DA6; -.
DR STRING; 159087.Daro_2440; -.
DR KEGG; dar:Daro_2440; -.
DR eggNOG; COG0677; Bacteria.
DR HOGENOM; CLU_023810_3_1_4; -.
DR OrthoDB; 9803238at2; -.
DR GO; GO:0051287; F:NAD binding; IEA:InterPro.
DR GO; GO:0016628; F:oxidoreductase activity, acting on the CH-CH group of donors, NAD or NADP as acceptor; IEA:InterPro.
DR GO; GO:0016616; F:oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor; IEA:InterPro.
DR GO; GO:0000271; P:polysaccharide biosynthetic process; IEA:InterPro.
DR Gene3D; 3.40.50.720; NAD(P)-binding Rossmann-like Domain; 2.
DR InterPro; IPR008927; 6-PGluconate_DH-like_C_sf.
DR InterPro; IPR036291; NAD(P)-bd_dom_sf.
DR InterPro; IPR017476; UDP-Glc/GDP-Man.
DR InterPro; IPR014027; UDP-Glc/GDP-Man_DH_C.
DR InterPro; IPR036220; UDP-Glc/GDP-Man_DH_C_sf.
DR InterPro; IPR014026; UDP-Glc/GDP-Man_DH_dimer.
DR InterPro; IPR001732; UDP-Glc/GDP-Man_DH_N.
DR InterPro; IPR028359; UDP_ManNAc/GlcNAc_DH.
DR NCBIfam; TIGR03026; NDP-sugDHase; 1.
DR PANTHER; PTHR43491; UDP-N-ACETYL-D-MANNOSAMINE DEHYDROGENASE; 1.
DR PANTHER; PTHR43491:SF2; UDP-N-ACETYL-D-MANNOSAMINE DEHYDROGENASE; 1.
DR Pfam; PF00984; UDPG_MGDP_dh; 1.
DR Pfam; PF03720; UDPG_MGDP_dh_C; 1.
DR Pfam; PF03721; UDPG_MGDP_dh_N; 1.
DR PIRSF; PIRSF500136; UDP_ManNAc_DH; 1.
DR PIRSF; PIRSF000124; UDPglc_GDPman_dh; 1.
DR SMART; SM00984; UDPG_MGDP_dh_C; 1.
DR SUPFAM; SSF48179; 6-phosphogluconate dehydrogenase C-terminal domain-like; 1.
DR SUPFAM; SSF51735; NAD(P)-binding Rossmann-fold domains; 1.
DR SUPFAM; SSF52413; UDP-glucose/GDP-mannose dehydrogenase C-terminal domain; 1.
PE 3: Inferred from homology;
KW NAD {ECO:0000256|ARBA:ARBA00023027};
KW Oxidoreductase {ECO:0000256|ARBA:ARBA00023002}.
FT DOMAIN 313..413
FT /note="UDP-glucose/GDP-mannose dehydrogenase C-terminal"
FT /evidence="ECO:0000259|SMART:SM00984"
SQ SEQUENCE 426 AA; 46367 MW; 4C027B359104D48E CRC64;
MTTIAVVGLG YVGLPLAVEF GKKYRTIGFD LSTHKIECYK KHYDPTGEVS TDDLKAATLL
EVGTDPAAIR EADFVVVAVP TPVDDAHQPD FSPLVGSSTA VGQNLKQGAI VVFESTVYPG
ATEEVCIPII ERESGKTWKK DFFVGYSPER INPGDKERTV TKIIKIVSGD TPETLATVQE
IYGSIITAGV YPASNIKVAE AAKVIENTQR DLNIALMNEL AIIFDKIGID TLEVLQAAGT
KWNFLPFRPG LVGGHCIGVD PYYLTHKAQK LGYHPEVILA GRRINDGMGK FIAEQTIKML
VKAGHPVKDC PIIVLGLTFK EDCPDLRNSR VIDVIRELES YGAKVVVHDP VADAAEARHE
YGVDLVAWND LPKAAAIVAA VNHKEYKALP IGDFLARLEK DGVIADVKSM LDSKAFSENG
ITVWRL
//
