ID   Q47RN0_THEFY            Unreviewed;       276 AA.
AC   Q47RN0;
DT   13-SEP-2005, integrated into UniProtKB/TrEMBL.
DT   13-SEP-2005, sequence version 1.
DT   27-MAR-2024, entry version 121.
DE   SubName: Full=Regulatory proteins, IclR {ECO:0000313|EMBL:AAZ54887.1};
GN   OrderedLocusNames=Tfu_0849 {ECO:0000313|EMBL:AAZ54887.1};
OS   Thermobifida fusca (strain YX).
OC   Bacteria; Actinomycetota; Actinomycetes; Streptosporangiales;
OC   Nocardiopsaceae; Thermobifida.
OX   NCBI_TaxID=269800 {ECO:0000313|EMBL:AAZ54887.1};
RN   [1] {ECO:0000313|EMBL:AAZ54887.1}
RP   NUCLEOTIDE SEQUENCE.
RC   STRAIN=YX {ECO:0000313|EMBL:AAZ54887.1};
RG   US DOE Joint Genome Institute;
RA   Copeland A., Lucas S., Lapidus A., Barry K., Detter J.C., Glavina T.,
RA   Hammon N., Israni S., Pitluck S., Di Bartolo G., Chain P., Schmutz J.,
RA   Larimer F., Land M., Lykidis A., Richardson P.;
RT   "Complete sequence of Thermobifida fusca YX.";
RL   Submitted (JUL-2005) to the EMBL/GenBank/DDBJ databases.
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DR   EMBL; CP000088; AAZ54887.1; -; Genomic_DNA.
DR   AlphaFoldDB; Q47RN0; -.
DR   STRING; 269800.Tfu_0849; -.
DR   KEGG; tfu:Tfu_0849; -.
DR   eggNOG; COG1414; Bacteria.
DR   HOGENOM; CLU_062618_6_3_11; -.
DR   GO; GO:0003677; F:DNA binding; IEA:InterPro.
DR   GO; GO:0006355; P:regulation of DNA-templated transcription; IEA:InterPro.
DR   Gene3D; 3.30.450.40; -; 1.
DR   Gene3D; 1.10.10.10; Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain; 1.
DR   InterPro; IPR029016; GAF-like_dom_sf.
DR   InterPro; IPR014757; Tscrpt_reg_IclR_C.
DR   InterPro; IPR005471; Tscrpt_reg_IclR_N.
DR   InterPro; IPR036388; WH-like_DNA-bd_sf.
DR   InterPro; IPR036390; WH_DNA-bd_sf.
DR   PANTHER; PTHR30136; HELIX-TURN-HELIX TRANSCRIPTIONAL REGULATOR, ICLR FAMILY; 1.
DR   PANTHER; PTHR30136:SF24; HTH-TYPE TRANSCRIPTIONAL REPRESSOR ALLR; 1.
DR   Pfam; PF09339; HTH_IclR; 1.
DR   Pfam; PF01614; IclR; 1.
DR   SMART; SM00346; HTH_ICLR; 1.
DR   SUPFAM; SSF55781; GAF domain-like; 1.
DR   SUPFAM; SSF46785; Winged helix' DNA-binding domain; 1.
DR   PROSITE; PS51077; HTH_ICLR; 1.
DR   PROSITE; PS51078; ICLR_ED; 1.
PE   4: Predicted;
KW   Transcription {ECO:0000256|ARBA:ARBA00023163};
KW   Transcription regulation {ECO:0000256|ARBA:ARBA00023015}.
FT   DOMAIN          32..93
FT                   /note="HTH iclR-type"
FT                   /evidence="ECO:0000259|PROSITE:PS51077"
FT   DOMAIN          94..273
FT                   /note="IclR-ED"
FT                   /evidence="ECO:0000259|PROSITE:PS51078"
FT   REGION          1..29
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        1..15
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   276 AA;  29298 MW;  D3AAAEA13A19E7B3 CRC64;
     MTTSQTATGD AGLDGMNGTT VTAGKRERSG GVQSLDRAFC LLEIMAEAGG ETSLSELAQS
     SGLPLPTIHR IVRSLVSNGY VRQLPSRRYA LGPRLIGLGE SASRLLGAWA RPHLARLVDE
     LGETANLAML DGDQVVYVAQ VPSAHAMRMF TEVGRRVLPH SAGVGKALLA QLPDDEALAI
     VRRTGMPAAT DRTITTPDEF AAELARIRSR GYAIDDGEQE VGVRCLAVPV VGGPAMMAIS
     ISGPESRMTW DFVAKAAPVV REVARELADD LNNQAR
//