ID Q47YW0_COLP3 Unreviewed; 983 AA.
AC Q47YW0;
DT 13-SEP-2005, integrated into UniProtKB/TrEMBL.
DT 13-SEP-2005, sequence version 1.
DT 27-MAR-2024, entry version 117.
DE SubName: Full=Serine protease, subtilase family {ECO:0000313|EMBL:AAZ23976.1};
DE EC=3.4.21.- {ECO:0000313|EMBL:AAZ23976.1};
GN OrderedLocusNames=CPS_3335 {ECO:0000313|EMBL:AAZ23976.1};
OS Colwellia psychrerythraea (strain 34H / ATCC BAA-681) (Vibrio
OS psychroerythus).
OC Bacteria; Pseudomonadota; Gammaproteobacteria; Alteromonadales;
OC Colwelliaceae; Colwellia.
OX NCBI_TaxID=167879 {ECO:0000313|EMBL:AAZ23976.1, ECO:0000313|Proteomes:UP000000547};
RN [1] {ECO:0000313|EMBL:AAZ23976.1}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=34H {ECO:0000313|EMBL:AAZ23976.1};
RX PubMed=16043709; DOI=10.1073/pnas.0504766102;
RA Methe B.A., Nelson K.E., Deming J.W., Momen B., Melamud E., Zhang X.,
RA Moult J., Madupu R., Nelson W.C., Dodson R.J., Brinkac L.M.,
RA Daugherty S.C., Durkin A.S., DeBoy R.T., Kolonay J.F., Sullivan S.A.,
RA Zhou L., Davidsen T.M., Wu M., Huston A.L., Lewis M., Weaver B.,
RA Weidman J.F., Khouri H., Utterback T.R., Feldblyum T.V., Fraser C.M.;
RT "The psychrophilic lifestyle as revealed by the genome sequence of
RT Colwellia psychrerythraea 34H through genomic and proteomic analyses.";
RL Proc. Natl. Acad. Sci. U.S.A. 102:10913-10918(2005).
CC -!- SIMILARITY: Belongs to the peptidase S8 family.
CC {ECO:0000256|ARBA:ARBA00011073, ECO:0000256|PROSITE-ProRule:PRU01240,
CC ECO:0000256|RuleBase:RU003355}.
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DR EMBL; CP000083; AAZ23976.1; -; Genomic_DNA.
DR RefSeq; WP_011044096.1; NC_003910.7.
DR AlphaFoldDB; Q47YW0; -.
DR STRING; 167879.CPS_3335; -.
DR KEGG; cps:CPS_3335; -.
DR HOGENOM; CLU_000625_3_0_6; -.
DR Proteomes; UP000000547; Chromosome.
DR GO; GO:0004252; F:serine-type endopeptidase activity; IEA:UniProtKB-UniRule.
DR GO; GO:0006508; P:proteolysis; IEA:UniProtKB-KW.
DR CDD; cd02120; PA_subtilisin_like; 1.
DR CDD; cd04852; Peptidases_S8_3; 1.
DR Gene3D; 2.60.120.380; -; 1.
DR Gene3D; 2.60.40.2310; -; 1.
DR Gene3D; 3.50.30.30; -; 1.
DR Gene3D; 3.30.70.80; Peptidase S8 propeptide/proteinase inhibitor I9; 1.
DR Gene3D; 3.40.50.200; Peptidase S8/S53 domain; 1.
DR InterPro; IPR046450; PA_dom_sf.
DR InterPro; IPR003137; PA_domain.
DR InterPro; IPR000209; Peptidase_S8/S53_dom.
DR InterPro; IPR036852; Peptidase_S8/S53_dom_sf.
DR InterPro; IPR023827; Peptidase_S8_Asp-AS.
DR InterPro; IPR023828; Peptidase_S8_Ser-AS.
DR InterPro; IPR015500; Peptidase_S8_subtilisin-rel.
DR InterPro; IPR034197; Peptidases_S8_3.
DR InterPro; IPR010259; S8pro/Inhibitor_I9.
DR InterPro; IPR037045; S8pro/Inhibitor_I9_sf.
DR InterPro; IPR045051; SBT.
DR InterPro; IPR041469; Subtilisin-like_FN3.
DR PANTHER; PTHR10795; PROPROTEIN CONVERTASE SUBTILISIN/KEXIN; 1.
DR PANTHER; PTHR10795:SF468; SUBTILISIN-LIKE PROTEASE SBT3.18; 1.
DR Pfam; PF17766; fn3_6; 1.
DR Pfam; PF05922; Inhibitor_I9; 1.
DR Pfam; PF02225; PA; 1.
DR Pfam; PF00082; Peptidase_S8; 1.
DR PRINTS; PR00723; SUBTILISIN.
DR SUPFAM; SSF52025; PA domain; 1.
DR SUPFAM; SSF52743; Subtilisin-like; 1.
DR PROSITE; PS51892; SUBTILASE; 1.
DR PROSITE; PS00136; SUBTILASE_ASP; 1.
DR PROSITE; PS00138; SUBTILASE_SER; 1.
PE 3: Inferred from homology;
KW Hydrolase {ECO:0000256|ARBA:ARBA00022801, ECO:0000256|PROSITE-
KW ProRule:PRU01240};
KW Protease {ECO:0000256|ARBA:ARBA00022670, ECO:0000256|PROSITE-
KW ProRule:PRU01240};
KW Serine protease {ECO:0000256|ARBA:ARBA00022825, ECO:0000256|PROSITE-
KW ProRule:PRU01240}.
FT DOMAIN 37..138
FT /note="Inhibitor I9"
FT /evidence="ECO:0000259|Pfam:PF05922"
FT DOMAIN 163..611
FT /note="Peptidase S8/S53"
FT /evidence="ECO:0000259|Pfam:PF00082"
FT DOMAIN 418..486
FT /note="PA"
FT /evidence="ECO:0000259|Pfam:PF02225"
FT DOMAIN 677..775
FT /note="Subtilisin-like protease fibronectin type-III"
FT /evidence="ECO:0000259|Pfam:PF17766"
FT REGION 243..265
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT ACT_SITE 172
FT /note="Charge relay system"
FT /evidence="ECO:0000256|PIRSR:PIRSR615500-1,
FT ECO:0000256|PROSITE-ProRule:PRU01240"
FT ACT_SITE 252
FT /note="Charge relay system"
FT /evidence="ECO:0000256|PIRSR:PIRSR615500-1,
FT ECO:0000256|PROSITE-ProRule:PRU01240"
FT ACT_SITE 565
FT /note="Charge relay system"
FT /evidence="ECO:0000256|PIRSR:PIRSR615500-1,
FT ECO:0000256|PROSITE-ProRule:PRU01240"
SQ SEQUENCE 983 AA; 101823 MW; 99AB9C822CE362E4 CRC64;
MKNILPLMWV IILMFVISQG VSAKGKKEIP KSEYGSYIVI MDLNPAIAYE GDIKGFKATK
PGKNKKINPK SANVRKYTSM LSKTHDAALA KANVKSKDKV HDYGIALNGF SAKMTHEQAV
ALSSQDGVAK VMPDVLRQKM TDNSPSFLDL GGPAGPWLKG YDGEGIVIGV IDTGIWPEHP
SFTDDGSYST PPILLDDSRP NCEFGNTGHR PDDVAFSCNN KLIGARQMLD TYRLIVGATS
DEFDSARDED GHGTHTSSTS GGNANVPANM LGNDYGLISG IAPRAHIVMY KGLGDLGGFG
SDLAAAIDQA VADGVDVINY SIGSSSFAIG PDDVAFLFAE NAGVFVATSN GNSGPAPATT
GSPASTPWVT SVGASTQNRT YQGSASSVGE WEFFGASITA GTAELALIDS AEAGSELCIP
GVLDPVAVAG KIVLCLRGAI ARVDKSKAVN IAGGAGMILY NANDGESQVT DSHWVPSVHI
NNTDGLVIKG YISNDASTAV AQIMGGTYTE IDAPSMAGFS SRGPNLLSGD IIKPDVTAPG
VNIIAGQTPA SEGRGELFQM ISGTSMSSPH VAGLFAMIKQ AHPNWSPSTA KSALMTTAYQ
DVMKEDEATP ADAFDMGAGH VNPGGKANKG SIFEPGLAYQ AGLFEYAAYS CGAELGIFSP
GTCGFLESLG IPTDPANLNL PSIGIANVIG SKTVYRSVTG VAKDSGWRTY SVDVDAPAGY
EVSVLPASIK LKSGMSATYA VTITNTASPA GEWAHGSITW RDSNDHYSVY SPIAVKGALF
EAPANITGSS ETGSASIDVT FGYTGDYTAS GYGLTAATVD IDSVVQDPDQ IFDPGDTFSN
AHAIVVSGAA YLRIAIPGVA DPNADLDIFL LDSVGNIVGV SANGGTDELI EMELPGDDTY
TLWVHGWSAP GGSTDYELYS WVVPMASGSL TVASAPSSAT LGATETIGVD WTGATNGKWH
FGVIGHSDAG GLIGATLVEV DNR
//
