ID P37_MYCGE Reviewed; 368 AA.
AC Q49410;
DT 01-NOV-1997, integrated into UniProtKB/Swiss-Prot.
DT 01-NOV-1996, sequence version 1.
DT 27-MAR-2024, entry version 117.
DE RecName: Full=High affinity transport system protein p37;
DE Flags: Precursor;
GN Name=p37; OrderedLocusNames=MG289;
OS Mycoplasma genitalium (strain ATCC 33530 / DSM 19775 / NCTC 10195 / G37)
OS (Mycoplasmoides genitalium).
OC Bacteria; Mycoplasmatota; Mycoplasmoidales; Mycoplasmoidaceae;
OC Mycoplasmoides.
OX NCBI_TaxID=243273;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC 33530 / DSM 19775 / NCTC 10195 / G37;
RX PubMed=7569993; DOI=10.1126/science.270.5235.397;
RA Fraser C.M., Gocayne J.D., White O., Adams M.D., Clayton R.A.,
RA Fleischmann R.D., Bult C.J., Kerlavage A.R., Sutton G.G., Kelley J.M.,
RA Fritchman J.L., Weidman J.F., Small K.V., Sandusky M., Fuhrmann J.L.,
RA Nguyen D.T., Utterback T.R., Saudek D.M., Phillips C.A., Merrick J.M.,
RA Tomb J.-F., Dougherty B.A., Bott K.F., Hu P.-C., Lucier T.S.,
RA Peterson S.N., Smith H.O., Hutchison C.A. III, Venter J.C.;
RT "The minimal gene complement of Mycoplasma genitalium.";
RL Science 270:397-403(1995).
CC -!- FUNCTION: P37 is part of a high-affinity transport system.
CC -!- SUBCELLULAR LOCATION: Cell membrane; Lipid-anchor.
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DR EMBL; L43967; AAC71510.1; -; Genomic_DNA.
DR PIR; I64231; I64231.
DR RefSeq; WP_009885873.1; NZ_AAGX01000008.1.
DR PDB; 3MYU; X-ray; 1.95 A; A/B=26-368.
DR PDBsum; 3MYU; -.
DR AlphaFoldDB; Q49410; -.
DR SMR; Q49410; -.
DR STRING; 243273.MG_289; -.
DR KEGG; mge:MG_289; -.
DR eggNOG; ENOG5031Y7G; Bacteria.
DR HOGENOM; CLU_055613_0_0_14; -.
DR InParanoid; Q49410; -.
DR OrthoDB; 401239at2; -.
DR BioCyc; MGEN243273:G1GJ2-357-MONOMER; -.
DR Proteomes; UP000000807; Chromosome.
DR GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
DR Gene3D; 3.40.190.190; CypI, domain 2; 1.
DR Gene3D; 3.40.190.180; Cypl, domain I; 1.
DR InterPro; IPR010592; CypI.
DR InterPro; IPR043099; CypI_dom_I.
DR InterPro; IPR043100; CypI_dom_II.
DR Pfam; PF06646; CypI; 1.
DR PIRSF; PIRSF004523; Mycoplasma_p37; 1.
DR PROSITE; PS51257; PROKAR_LIPOPROTEIN; 1.
PE 1: Evidence at protein level;
KW 3D-structure; Cell membrane; Lipoprotein; Membrane; Palmitate;
KW Reference proteome; Signal; Transport.
FT SIGNAL 1..25
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00303"
FT CHAIN 26..368
FT /note="High affinity transport system protein p37"
FT /id="PRO_0000018094"
FT LIPID 26
FT /note="N-palmitoyl cysteine"
FT /evidence="ECO:0000305"
FT LIPID 26
FT /note="S-diacylglycerol cysteine"
FT /evidence="ECO:0000305"
FT STRAND 33..38
FT /evidence="ECO:0007829|PDB:3MYU"
FT HELIX 44..46
FT /evidence="ECO:0007829|PDB:3MYU"
FT HELIX 48..63
FT /evidence="ECO:0007829|PDB:3MYU"
FT STRAND 68..73
FT /evidence="ECO:0007829|PDB:3MYU"
FT HELIX 77..85
FT /evidence="ECO:0007829|PDB:3MYU"
FT STRAND 90..94
FT /evidence="ECO:0007829|PDB:3MYU"
FT HELIX 96..98
FT /evidence="ECO:0007829|PDB:3MYU"
FT STRAND 105..118
FT /evidence="ECO:0007829|PDB:3MYU"
FT HELIX 127..129
FT /evidence="ECO:0007829|PDB:3MYU"
FT HELIX 131..144
FT /evidence="ECO:0007829|PDB:3MYU"
FT HELIX 148..150
FT /evidence="ECO:0007829|PDB:3MYU"
FT TURN 153..157
FT /evidence="ECO:0007829|PDB:3MYU"
FT STRAND 160..163
FT /evidence="ECO:0007829|PDB:3MYU"
FT HELIX 164..166
FT /evidence="ECO:0007829|PDB:3MYU"
FT STRAND 167..185
FT /evidence="ECO:0007829|PDB:3MYU"
FT HELIX 186..198
FT /evidence="ECO:0007829|PDB:3MYU"
FT HELIX 201..205
FT /evidence="ECO:0007829|PDB:3MYU"
FT STRAND 209..211
FT /evidence="ECO:0007829|PDB:3MYU"
FT TURN 217..220
FT /evidence="ECO:0007829|PDB:3MYU"
FT HELIX 221..231
FT /evidence="ECO:0007829|PDB:3MYU"
FT HELIX 238..244
FT /evidence="ECO:0007829|PDB:3MYU"
FT HELIX 246..248
FT /evidence="ECO:0007829|PDB:3MYU"
FT STRAND 249..251
FT /evidence="ECO:0007829|PDB:3MYU"
FT HELIX 254..256
FT /evidence="ECO:0007829|PDB:3MYU"
FT STRAND 265..269
FT /evidence="ECO:0007829|PDB:3MYU"
FT HELIX 272..275
FT /evidence="ECO:0007829|PDB:3MYU"
FT STRAND 294..306
FT /evidence="ECO:0007829|PDB:3MYU"
FT STRAND 309..313
FT /evidence="ECO:0007829|PDB:3MYU"
FT HELIX 318..333
FT /evidence="ECO:0007829|PDB:3MYU"
FT HELIX 340..343
FT /evidence="ECO:0007829|PDB:3MYU"
FT STRAND 347..350
FT /evidence="ECO:0007829|PDB:3MYU"
FT HELIX 354..357
FT /evidence="ECO:0007829|PDB:3MYU"
FT HELIX 359..366
FT /evidence="ECO:0007829|PDB:3MYU"
SQ SEQUENCE 368 AA; 42258 MW; 6286532E78DA96E3 CRC64;
MLFKKFTWVI PSLFLTIIST SLLISCATKS DNTLIFNISL DHNADTSIEK FFTVFSKKLS
GKLNKKINVN FNIVDDSFTK INNIQANKAD FAFVNSQAIA SNNWFGYTPL IQTLTTAFKE
DLELDYYEDG NLQKKAEKTN LLFLSPPYKE WDDIKQKWTG NRYDFLYEPS KLVSFYRSMI
LITGSASEIT AIKKAWNEKN WNQFMKFGIG HGQTNSASRF ELPDLLFRKH FAKNYPGLQN
AINSDPDKFA VVRGREIGIN KNIKIVFDDA NSFSWTQNIK GSKRPFYTPI DPNDRLEILT
YSDPLLYDIG IVSNNLSRIY QKAIGEIFIE LAQSSEDLYG PSIGYNGYKM INDFEKEVVE
IIEKTYGK
//
