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Database: UniProt
Entry: Q49X94
LinkDB: Q49X94
Original site: Q49X94 
ID   GLPD_STAS1              Reviewed;         557 AA.
AC   Q49X94;
DT   09-JAN-2007, integrated into UniProtKB/Swiss-Prot.
DT   13-SEP-2005, sequence version 1.
DT   16-JAN-2019, entry version 90.
DE   RecName: Full=Aerobic glycerol-3-phosphate dehydrogenase;
DE            EC=1.1.5.3;
GN   Name=glpD; OrderedLocusNames=SSP1459;
OS   Staphylococcus saprophyticus subsp. saprophyticus (strain ATCC 15305 /
OS   DSM 20229).
OC   Bacteria; Firmicutes; Bacilli; Bacillales; Staphylococcaceae;
OC   Staphylococcus.
OX   NCBI_TaxID=342451;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC 15305 / DSM 20229;
RX   PubMed=16135568; DOI=10.1073/pnas.0502950102;
RA   Kuroda M., Yamashita A., Hirakawa H., Kumano M., Morikawa K.,
RA   Higashide M., Maruyama A., Inose Y., Matoba K., Toh H., Kuhara S.,
RA   Hattori M., Ohta T.;
RT   "Whole genome sequence of Staphylococcus saprophyticus reveals the
RT   pathogenesis of uncomplicated urinary tract infection.";
RL   Proc. Natl. Acad. Sci. U.S.A. 102:13272-13277(2005).
CC   -!- CATALYTIC ACTIVITY:
CC       Reaction=a quinone + sn-glycerol 3-phosphate = a quinol +
CC         dihydroxyacetone phosphate; Xref=Rhea:RHEA:18977,
CC         ChEBI:CHEBI:24646, ChEBI:CHEBI:57597, ChEBI:CHEBI:57642,
CC         ChEBI:CHEBI:132124; EC=1.1.5.3;
CC   -!- COFACTOR:
CC       Name=FAD; Xref=ChEBI:CHEBI:57692; Evidence={ECO:0000250};
CC   -!- PATHWAY: Polyol metabolism; glycerol degradation via glycerol
CC       kinase pathway; glycerone phosphate from sn-glycerol 3-phosphate
CC       (aerobic route): step 1/1.
CC   -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000250}.
CC   -!- SIMILARITY: Belongs to the FAD-dependent glycerol-3-phosphate
CC       dehydrogenase family. {ECO:0000305}.
DR   EMBL; AP008934; BAE18604.1; -; Genomic_DNA.
DR   RefSeq; WP_011303227.1; NZ_MTGA01000034.1.
DR   ProteinModelPortal; Q49X94; -.
DR   SMR; Q49X94; -.
DR   STRING; 342451.SSP1459; -.
DR   PRIDE; Q49X94; -.
DR   EnsemblBacteria; BAE18604; BAE18604; SSP1459.
DR   GeneID; 3615086; -.
DR   KEGG; ssp:SSP1459; -.
DR   PATRIC; fig|342451.11.peg.1463; -.
DR   eggNOG; ENOG4105C6V; Bacteria.
DR   eggNOG; COG0578; LUCA.
DR   HOGENOM; HOG000004812; -.
DR   KO; K00111; -.
DR   OMA; MDNPTVK; -.
DR   OrthoDB; 360065at2; -.
DR   BioCyc; SSAP342451:G1G2H-1476-MONOMER; -.
DR   UniPathway; UPA00618; UER00674.
DR   Proteomes; UP000006371; Chromosome.
DR   GO; GO:0009331; C:glycerol-3-phosphate dehydrogenase complex; IEA:InterPro.
DR   GO; GO:0052591; F:sn-glycerol-3-phosphate:ubiquinone-8 oxidoreductase activity; IEA:UniProtKB-EC.
DR   GO; GO:0019563; P:glycerol catabolic process; IEA:UniProtKB-UniPathway.
DR   GO; GO:0006072; P:glycerol-3-phosphate metabolic process; IEA:InterPro.
DR   Gene3D; 1.10.8.870; -; 1.
DR   Gene3D; 3.50.50.60; -; 1.
DR   InterPro; IPR031656; DAO_C.
DR   InterPro; IPR038299; DAO_C_sf.
DR   InterPro; IPR006076; FAD-dep_OxRdtase.
DR   InterPro; IPR036188; FAD/NAD-bd_sf.
DR   InterPro; IPR000447; G3P_DH_FAD-dep.
DR   PANTHER; PTHR11985; PTHR11985; 1.
DR   Pfam; PF01266; DAO; 1.
DR   Pfam; PF16901; DAO_C; 1.
DR   PRINTS; PR01001; FADG3PDH.
DR   SUPFAM; SSF51905; SSF51905; 1.
DR   PROSITE; PS00977; FAD_G3PDH_1; 1.
DR   PROSITE; PS00978; FAD_G3PDH_2; 1.
PE   3: Inferred from homology;
KW   Complete proteome; Cytoplasm; FAD; Flavoprotein; Glycerol metabolism;
KW   Oxidoreductase.
FT   CHAIN         1    557       Aerobic glycerol-3-phosphate
FT                                dehydrogenase.
FT                                /FTId=PRO_0000270068.
FT   NP_BIND      21     49       FAD. {ECO:0000255}.
SQ   SEQUENCE   557 AA;  62260 MW;  519E5CAF87EC8989 CRC64;
     MSLSTLKREQ IKKDLKDQEF DVVIIGGGIT GAGIALDASE RGMKVALVEM QDFAQGTSSR
     STKLVHGGLR YLKQLQVGVV AETGRERAIV YENGPHVTTP ERMLLPMHKG GSMGKFTTSI
     GLAMYDRLAG VKKAERKTML NAKETLEKEP LVKKAGLKGG GSYVEYRTDD ARLTIEVMKR
     AEEKGAKVIN HTKSVHFTYD SNEKVNGIQV EDQISNETYP IKAKKVINAS GPWVDEVRSG
     DYARNNKQLR LTKGVHIVID QSKFPLGQAV YFDTEKDGRM IFAIPREGKA YVGTTDTFYD
     NNKTSPLANQ EDRDYLIDAI NYMFPDVNVA DEDIESSWAG VRPLILEEGK DPSEISRKDE
     VWEGKSGLLT IAGGKLTGYR HMALEIVDLL SKRLKSEFGL KFDKCATKHL TISGGDVGGS
     ANFDKFIEQK VEEAKSYQID ESTARHFASK YGSNAEELFK IAQTAQYQET GLPLDIYTEL
     VYSIQNEMVY RPTDFFIRRT GKLYFKIDDV LNYKEQVIDV MAGLLGYTNI EKEAYTKELQ
     IAIDEAQTGN HQPAVKE
//
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