ID Q4C263_CROWT Unreviewed; 506 AA.
AC Q4C263;
DT 13-SEP-2005, integrated into UniProtKB/TrEMBL.
DT 13-SEP-2005, sequence version 1.
DT 27-MAR-2024, entry version 66.
DE SubName: Full=Peptidase M50 {ECO:0000313|EMBL:EAM50235.1};
DE Flags: Precursor;
GN ORFNames=CwatDRAFT_2742 {ECO:0000313|EMBL:EAM50235.1};
OS Crocosphaera watsonii WH 8501.
OC Bacteria; Cyanobacteriota; Cyanophyceae; Oscillatoriophycideae;
OC Chroococcales; Aphanothecaceae; Crocosphaera.
OX NCBI_TaxID=165597 {ECO:0000313|EMBL:EAM50235.1, ECO:0000313|Proteomes:UP000003922};
RN [1] {ECO:0000313|EMBL:EAM50235.1, ECO:0000313|Proteomes:UP000003922}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=WH 8501 {ECO:0000313|EMBL:EAM50235.1,
RC ECO:0000313|Proteomes:UP000003922};
RG DOE Joint Genome Institute;
RL Submitted (FEB-2004) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|EMBL:EAM50235.1, ECO:0000313|Proteomes:UP000003922}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=WH 8501 {ECO:0000313|EMBL:EAM50235.1,
RC ECO:0000313|Proteomes:UP000003922};
RG US DOE Joint Genome Institute (JGI-ORNL);
RA Larimer F., Land M.;
RT "Annotation of the draft genome assembly of Crocosphaera watsonii WH
RT 8501.";
RL Submitted (JUN-2005) to the EMBL/GenBank/DDBJ databases.
RN [3] {ECO:0000313|EMBL:EAM50235.1, ECO:0000313|Proteomes:UP000003922}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=WH 8501 {ECO:0000313|EMBL:EAM50235.1,
RC ECO:0000313|Proteomes:UP000003922};
RG US DOE Joint Genome Institute (JGI-PGF);
RA Copeland A., Lucas S., Lapidus A., Barry K., Detter C., Glavina T.,
RA Hammon N., Israni S., Pitluck S., Richardson P.;
RT "Sequencing of the draft genome and assembly of Crocosphaera watsonii WH
RT 8501.";
RL Submitted (JUN-2005) to the EMBL/GenBank/DDBJ databases.
CC -!- COFACTOR:
CC Name=Zn(2+); Xref=ChEBI:CHEBI:29105;
CC Evidence={ECO:0000256|ARBA:ARBA00001947};
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-
CC pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
CC -!- SIMILARITY: Belongs to the peptidase M50B family.
CC {ECO:0000256|ARBA:ARBA00007931}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:EAM50235.1}.
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DR EMBL; AADV02000033; EAM50235.1; -; Genomic_DNA.
DR RefSeq; WP_007306071.1; NZ_AADV02000033.1.
DR AlphaFoldDB; Q4C263; -.
DR KEGG; cwa:CwatDRAFT_2742; -.
DR OrthoDB; 494312at2; -.
DR Proteomes; UP000003922; Unassembled WGS sequence.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0006508; P:proteolysis; IEA:InterPro.
DR CDD; cd06160; S2P-M50_like_2; 1.
DR InterPro; IPR044838; EGY1-like.
DR InterPro; IPR008915; Peptidase_M50.
DR PANTHER; PTHR31412; ZINC METALLOPROTEASE EGY1; 1.
DR PANTHER; PTHR31412:SF5; ZINC METALLOPROTEASE EGY2, CHLOROPLASTIC-RELATED; 1.
DR Pfam; PF02163; Peptidase_M50; 1.
PE 3: Inferred from homology;
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000003922};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}.
FT TRANSMEM 6..25
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 37..58
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 227..249
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 255..275
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 319..345
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 389..408
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 428..457
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 477..499
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 266..428
FT /note="Peptidase M50"
FT /evidence="ECO:0000259|Pfam:PF02163"
FT REGION 104..124
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 506 AA; 55572 MW; 2F731D3679366762 CRC64;
MLNTQETTTI LVIILVAFGL LAWGYNRAKG YGKLGKLAWL QSVSLMTPWL VFFGLFALGI
YLNIVGILFL LVASIISYIY LGKKLRSEGQ DVMLQNEAAQ RIQEEEAKKD ENKTPSLTTE
FNDSSDNKNI SDLIPIPDED LQLIKGIFSI DTFFATETIS YQEGAIFRGN LRGETEESYQ
KLSEKLKDSF GEKYRLFLVE GSEGKPVVII LPSSDDPQPT TLVQKNLALV LLVGTVFTTL
EAASILLGFD LFNNWGRYIE TLPIGLALWG IFIFHEVGHR VAAKRYDIKM SVPFFLPTWR
IGSFGAITRF ESLIPTRNAL FDVALAGPAC GGILSFILLI IGLVLSHDGS LFQVPTQFFQ
GSILVGSLAK VVLGEQLQNA IVDVHPLTVV GWLGLVVTAL NLMPAGQLDG GRIIQAIYGR
KTARRATIIT LVILGIVTIF SPANPIPLYW AVVILFLQRD LERPSLNELT EPDDTRAGWG
LLALFLMLAT LIPLSPALAG RLGIGG
//
