ID Q4CAR4_CROWT Unreviewed; 462 AA.
AC Q4CAR4;
DT 13-SEP-2005, integrated into UniProtKB/TrEMBL.
DT 13-SEP-2005, sequence version 1.
DT 27-MAR-2024, entry version 47.
DE SubName: Full=Retinal pigment epithelial membrane protein {ECO:0000313|EMBL:EAM52872.1};
GN ORFNames=CwatDRAFT_6676 {ECO:0000313|EMBL:EAM52872.1};
OS Crocosphaera watsonii WH 8501.
OC Bacteria; Cyanobacteriota; Cyanophyceae; Oscillatoriophycideae;
OC Chroococcales; Aphanothecaceae; Crocosphaera.
OX NCBI_TaxID=165597 {ECO:0000313|EMBL:EAM52872.1, ECO:0000313|Proteomes:UP000003922};
RN [1] {ECO:0000313|EMBL:EAM52872.1, ECO:0000313|Proteomes:UP000003922}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=WH 8501 {ECO:0000313|EMBL:EAM52872.1,
RC ECO:0000313|Proteomes:UP000003922};
RG DOE Joint Genome Institute;
RL Submitted (FEB-2004) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|EMBL:EAM52872.1, ECO:0000313|Proteomes:UP000003922}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=WH 8501 {ECO:0000313|EMBL:EAM52872.1,
RC ECO:0000313|Proteomes:UP000003922};
RG US DOE Joint Genome Institute (JGI-ORNL);
RA Larimer F., Land M.;
RT "Annotation of the draft genome assembly of Crocosphaera watsonii WH
RT 8501.";
RL Submitted (JUN-2005) to the EMBL/GenBank/DDBJ databases.
RN [3] {ECO:0000313|EMBL:EAM52872.1, ECO:0000313|Proteomes:UP000003922}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=WH 8501 {ECO:0000313|EMBL:EAM52872.1,
RC ECO:0000313|Proteomes:UP000003922};
RG US DOE Joint Genome Institute (JGI-PGF);
RA Copeland A., Lucas S., Lapidus A., Barry K., Detter C., Glavina T.,
RA Hammon N., Israni S., Pitluck S., Richardson P.;
RT "Sequencing of the draft genome and assembly of Crocosphaera watsonii WH
RT 8501.";
RL Submitted (JUN-2005) to the EMBL/GenBank/DDBJ databases.
CC -!- COFACTOR:
CC Name=Fe(2+); Xref=ChEBI:CHEBI:29033;
CC Evidence={ECO:0000256|PIRSR:PIRSR604294-1};
CC Note=Binds 1 Fe(2+) ion per subunit. {ECO:0000256|PIRSR:PIRSR604294-1};
CC -!- SIMILARITY: Belongs to the carotenoid oxygenase family.
CC {ECO:0000256|ARBA:ARBA00006787}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:EAM52872.1}.
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DR EMBL; AADV02000001; EAM52872.1; -; Genomic_DNA.
DR RefSeq; WP_007303189.1; NZ_AADV02000001.1.
DR AlphaFoldDB; Q4CAR4; -.
DR KEGG; cwa:CwatDRAFT_6676; -.
DR OrthoDB; 6636843at2; -.
DR Proteomes; UP000003922; Unassembled WGS sequence.
DR GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR GO; GO:0016702; F:oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen; IEA:InterPro.
DR InterPro; IPR004294; Carotenoid_Oase.
DR PANTHER; PTHR10543; BETA-CAROTENE DIOXYGENASE; 1.
DR PANTHER; PTHR10543:SF89; CAROTENOID 9,10(9',10')-CLEAVAGE DIOXYGENASE 1; 1.
DR Pfam; PF03055; RPE65; 1.
PE 3: Inferred from homology;
KW Iron {ECO:0000256|ARBA:ARBA00023004, ECO:0000256|PIRSR:PIRSR604294-1};
KW Metal-binding {ECO:0000256|ARBA:ARBA00022723,
KW ECO:0000256|PIRSR:PIRSR604294-1};
KW Oxidoreductase {ECO:0000256|ARBA:ARBA00023002};
KW Reference proteome {ECO:0000313|Proteomes:UP000003922}.
FT BINDING 165
FT /ligand="Fe cation"
FT /ligand_id="ChEBI:CHEBI:24875"
FT /ligand_note="catalytic"
FT /evidence="ECO:0000256|PIRSR:PIRSR604294-1"
FT BINDING 214
FT /ligand="Fe cation"
FT /ligand_id="ChEBI:CHEBI:24875"
FT /ligand_note="catalytic"
FT /evidence="ECO:0000256|PIRSR:PIRSR604294-1"
FT BINDING 278
FT /ligand="Fe cation"
FT /ligand_id="ChEBI:CHEBI:24875"
FT /ligand_note="catalytic"
FT /evidence="ECO:0000256|PIRSR:PIRSR604294-1"
FT BINDING 453
FT /ligand="Fe cation"
FT /ligand_id="ChEBI:CHEBI:24875"
FT /ligand_note="catalytic"
FT /evidence="ECO:0000256|PIRSR:PIRSR604294-1"
SQ SEQUENCE 462 AA; 52179 MW; FCE1A6348DBC7B4A CRC64;
MTATISINPY LSGNFAPVNQ ETTENNLTVI GEIPRNLRGM FLRNGPNPQF LPIGQYHWFD
GDGMIHGVHI ENGKASYRNR FVQTRGYGLE KEANKPLWTG LLEPPQMDNP YGTSKNPANT
ALVYHAGRLL ALWEGGEPHA LTVPELNSLG SYNFDNKLVS PFTAHPKVDP VTGEMMFFGY
SFAQPPYLQY GIISPQGELL RTVPIDIPVG VMMHDCAITE NYTIFLDLPL TFRPERMYKG
EPPLQFEHNT PSRFGITPRQ GNNEDVRWFE SDSCYIFHTL NAYEEGDEVV LIACRMNATT
VLGEANEDVK DSDIPRLHQW RFNLTTGEVK EQPLCDLPSE FPRINEQYTG RKTRYGYSGK
MAASSEPKFD GIIKHDFEKG NFEIHNFGSH RYGGEPIFAP NPSAVTDEQG WLLTFVYDEA
SKVSELVIID AQDFTASPVA KIQIPQRVPY GFHGMWLNEV RS
//
