ID Q4CMU9_TRYCC Unreviewed; 263 AA.
AC Q4CMU9;
DT 13-SEP-2005, integrated into UniProtKB/TrEMBL.
DT 13-SEP-2005, sequence version 1.
DT 08-NOV-2023, entry version 61.
DE SubName: Full=Trans-sialidase, putative {ECO:0000313|EMBL:EAN81601.1};
GN ORFNames=Tc00.1047053503659.30 {ECO:0000313|EMBL:EAN81601.1};
OS Trypanosoma cruzi (strain CL Brener).
OC Eukaryota; Discoba; Euglenozoa; Kinetoplastea; Metakinetoplastina;
OC Trypanosomatida; Trypanosomatidae; Trypanosoma; Schizotrypanum.
OX NCBI_TaxID=353153 {ECO:0000313|EMBL:EAN81601.1, ECO:0000313|Proteomes:UP000002296};
RN [1] {ECO:0000313|EMBL:EAN81601.1, ECO:0000313|Proteomes:UP000002296}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=CL Brener {ECO:0000313|EMBL:EAN81601.1,
RC ECO:0000313|Proteomes:UP000002296};
RX PubMed=16020725; DOI=10.1126/science.1112631;
RA El-Sayed N.M., Myler P.J., Bartholomeu D.C., Nilsson D., Aggarwal G.,
RA Tran A.N., Ghedin E., Worthey E.A., Delcher A.L., Blandin G.,
RA Westenberger S.J., Caler E., Cerqueira G.C., Branche C., Haas B.,
RA Anupama A., Arner E., Aslund L., Attipoe P., Bontempi E., Bringaud F.,
RA Burton P., Cadag E., Campbell D.A., Carrington M., Crabtree J., Darban H.,
RA da Silveira J.F., de Jong P., Edwards K., Englund P.T., Fazelina G.,
RA Feldblyum T., Ferella M., Frasch A.C., Gull K., Horn D., Hou L., Huang Y.,
RA Kindlund E., Klingbeil M., Kluge S., Koo H., Lacerda D., Levin M.J.,
RA Lorenzi H., Louie T., Machado C.R., McCulloch R., McKenna A., Mizuno Y.,
RA Mottram J.C., Nelson S., Ochaya S., Osoegawa K., Pai G., Parsons M.,
RA Pentony M., Pettersson U., Pop M., Ramirez J.L., Rinta J., Robertson L.,
RA Salzberg S.L., Sanchez D.O., Seyler A., Sharma R., Shetty J., Simpson A.J.,
RA Sisk E., Tammi M.T., Tarleton R., Teixeira S., Van Aken S., Vogt C.,
RA Ward P.N., Wickstead B., Wortman J., White O., Fraser C.M., Stuart K.D.,
RA Andersson B.;
RT "The genome sequence of Trypanosoma cruzi, etiologic agent of Chagas
RT disease.";
RL Science 309:409-415(2005).
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:EAN81601.1}.
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DR EMBL; AAHK01003230; EAN81601.1; -; Genomic_DNA.
DR RefSeq; XP_803047.1; XM_797954.1.
DR AlphaFoldDB; Q4CMU9; -.
DR SMR; Q4CMU9; -.
DR PaxDb; 353153-Q4CMU9; -.
DR EnsemblProtists; EAN81601; EAN81601; Tc00.1047053503659.30.
DR GeneID; 3532566; -.
DR KEGG; tcr:503659.30; -.
DR InParanoid; Q4CMU9; -.
DR OMA; THEWNDE; -.
DR OrthoDB; 139391at2759; -.
DR Proteomes; UP000002296; Unassembled WGS sequence.
DR GO; GO:0004308; F:exo-alpha-sialidase activity; IEA:InterPro.
DR Gene3D; 2.60.120.200; -; 1.
DR InterPro; IPR013320; ConA-like_dom_sf.
DR InterPro; IPR008377; Sialidase_trypan.
DR InterPro; IPR021287; Trans-sialidase_CS.
DR Pfam; PF13385; Laminin_G_3; 1.
DR Pfam; PF11052; Tr-sialidase_C; 1.
DR PRINTS; PR01803; TCSIALIDASE.
DR SUPFAM; SSF49899; Concanavalin A-like lectins/glucanases; 1.
PE 4: Predicted;
KW Reference proteome {ECO:0000313|Proteomes:UP000002296}.
FT REGION 192..240
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 207..230
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT NON_TER 1
FT /evidence="ECO:0000313|EMBL:EAN81601.1"
SQ SEQUENCE 263 AA; 27574 MW; 79023BC5CC43D7CA CRC64;
LGVYATVTGP AKKTEPSDGV TFKGRGAGAE WPVGKQGENQ LYHFANYNFT LVATVSIHGE
PKSGSVPLMG VRAGSDGVTK LVELSYGSGK KWRALCGDRT TAEHSSTWEA EKTYQVAIVL
QNGAQGSVYV DGQRVCESVQ NNLENTESKG ISHFYIGGDG VNAENTAGDE DVSVTVSNVL
LYNRPLTFTG GSADLEEDIA PPSEAPVEQA ASQQSRKKSE EQQVPAASSS HAVGEATGDG
GTVRGSGLLP LLLLLGLWVF SAL
//
