ID Q4CPG0_TRYCC Unreviewed; 298 AA.
AC Q4CPG0;
DT 13-SEP-2005, integrated into UniProtKB/TrEMBL.
DT 13-SEP-2005, sequence version 1.
DT 24-JAN-2024, entry version 63.
DE RecName: Full=Metallo-beta-lactamase domain-containing protein {ECO:0000259|Pfam:PF00753};
GN ORFNames=Tc00.1047053508691.20 {ECO:0000313|EMBL:EAN82163.1};
OS Trypanosoma cruzi (strain CL Brener).
OC Eukaryota; Discoba; Euglenozoa; Kinetoplastea; Metakinetoplastina;
OC Trypanosomatida; Trypanosomatidae; Trypanosoma; Schizotrypanum.
OX NCBI_TaxID=353153 {ECO:0000313|EMBL:EAN82163.1, ECO:0000313|Proteomes:UP000002296};
RN [1] {ECO:0000313|EMBL:EAN82163.1, ECO:0000313|Proteomes:UP000002296}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=CL Brener {ECO:0000313|EMBL:EAN82163.1,
RC ECO:0000313|Proteomes:UP000002296};
RX PubMed=16020725; DOI=10.1126/science.1112631;
RA El-Sayed N.M., Myler P.J., Bartholomeu D.C., Nilsson D., Aggarwal G.,
RA Tran A.N., Ghedin E., Worthey E.A., Delcher A.L., Blandin G.,
RA Westenberger S.J., Caler E., Cerqueira G.C., Branche C., Haas B.,
RA Anupama A., Arner E., Aslund L., Attipoe P., Bontempi E., Bringaud F.,
RA Burton P., Cadag E., Campbell D.A., Carrington M., Crabtree J., Darban H.,
RA da Silveira J.F., de Jong P., Edwards K., Englund P.T., Fazelina G.,
RA Feldblyum T., Ferella M., Frasch A.C., Gull K., Horn D., Hou L., Huang Y.,
RA Kindlund E., Klingbeil M., Kluge S., Koo H., Lacerda D., Levin M.J.,
RA Lorenzi H., Louie T., Machado C.R., McCulloch R., McKenna A., Mizuno Y.,
RA Mottram J.C., Nelson S., Ochaya S., Osoegawa K., Pai G., Parsons M.,
RA Pentony M., Pettersson U., Pop M., Ramirez J.L., Rinta J., Robertson L.,
RA Salzberg S.L., Sanchez D.O., Seyler A., Sharma R., Shetty J., Simpson A.J.,
RA Sisk E., Tammi M.T., Tarleton R., Teixeira S., Van Aken S., Vogt C.,
RA Ward P.N., Wickstead B., Wortman J., White O., Fraser C.M., Stuart K.D.,
RA Andersson B.;
RT "The genome sequence of Trypanosoma cruzi, etiologic agent of Chagas
RT disease.";
RL Science 309:409-415(2005).
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:EAN82163.1}.
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DR EMBL; AAHK01002653; EAN82163.1; -; Genomic_DNA.
DR RefSeq; XP_804014.1; XM_798921.1.
DR AlphaFoldDB; Q4CPG0; -.
DR SMR; Q4CPG0; -.
DR STRING; 353153.Q4CPG0; -.
DR PaxDb; 353153-Q4CPG0; -.
DR EnsemblProtists; EAN82163; EAN82163; Tc00.1047053508691.20.
DR GeneID; 3533332; -.
DR KEGG; tcr:508691.20; -.
DR eggNOG; KOG0813; Eukaryota.
DR InParanoid; Q4CPG0; -.
DR OrthoDB; 5471651at2759; -.
DR Proteomes; UP000002296; Unassembled WGS sequence.
DR Gene3D; 3.60.15.10; Ribonuclease Z/Hydroxyacylglutathione hydrolase-like; 1.
DR InterPro; IPR001279; Metallo-B-lactamas.
DR InterPro; IPR036866; RibonucZ/Hydroxyglut_hydro.
DR PANTHER; PTHR11935; BETA LACTAMASE DOMAIN; 1.
DR PANTHER; PTHR11935:SF94; TENZING NORGAY, ISOFORM C; 1.
DR Pfam; PF00753; Lactamase_B; 1.
DR SUPFAM; SSF56281; Metallo-hydrolase/oxidoreductase; 1.
PE 4: Predicted;
KW Reference proteome {ECO:0000313|Proteomes:UP000002296}.
FT DOMAIN 164..233
FT /note="Metallo-beta-lactamase"
FT /evidence="ECO:0000259|Pfam:PF00753"
SQ SEQUENCE 298 AA; 33404 MW; F18EE152F3A070B1 CRC64;
MTTLVRRSGI EIKQLMGVSL LLGLFGSLCI SGVTSLPTTV AMTFLCYLSG IVPENDYFPR
VWFKNNIFTW VYRIYCSDSI GYKYLRPMLH VRHGLPHSDY RHGVRSLSGG HKASSLFPVE
LKKNPEFYER GGGLVDLKGL GEEYKKGYRG VAVVPVPLLA DNYAYLILSF STKKCAVVDP
ADPKLVMYML TVVRYLTGVE FVLTDILTTH KHWDHAGGNL EFMQRLQNKS DAETTELLDA
QLKIYGSAID NPHACTNFVE DGNVLTVAGG GVTVAVFSSP WTHRWLRKIP FRRCSHGF
//
