ID Q4D8Z5_TRYCC Unreviewed; 400 AA.
AC Q4D8Z5;
DT 13-SEP-2005, integrated into UniProtKB/TrEMBL.
DT 13-SEP-2005, sequence version 1.
DT 27-MAR-2024, entry version 95.
DE RecName: Full=RING-type domain-containing protein {ECO:0000259|PROSITE:PS50089};
GN ORFNames=Tc00.1047053510351.50 {ECO:0000313|EMBL:EAN88989.1};
OS Trypanosoma cruzi (strain CL Brener).
OC Eukaryota; Discoba; Euglenozoa; Kinetoplastea; Metakinetoplastina;
OC Trypanosomatida; Trypanosomatidae; Trypanosoma; Schizotrypanum.
OX NCBI_TaxID=353153 {ECO:0000313|EMBL:EAN88989.1, ECO:0000313|Proteomes:UP000002296};
RN [1] {ECO:0000313|EMBL:EAN88989.1, ECO:0000313|Proteomes:UP000002296}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=CL Brener {ECO:0000313|EMBL:EAN88989.1,
RC ECO:0000313|Proteomes:UP000002296};
RX PubMed=16020725; DOI=10.1126/science.1112631;
RA El-Sayed N.M., Myler P.J., Bartholomeu D.C., Nilsson D., Aggarwal G.,
RA Tran A.N., Ghedin E., Worthey E.A., Delcher A.L., Blandin G.,
RA Westenberger S.J., Caler E., Cerqueira G.C., Branche C., Haas B.,
RA Anupama A., Arner E., Aslund L., Attipoe P., Bontempi E., Bringaud F.,
RA Burton P., Cadag E., Campbell D.A., Carrington M., Crabtree J., Darban H.,
RA da Silveira J.F., de Jong P., Edwards K., Englund P.T., Fazelina G.,
RA Feldblyum T., Ferella M., Frasch A.C., Gull K., Horn D., Hou L., Huang Y.,
RA Kindlund E., Klingbeil M., Kluge S., Koo H., Lacerda D., Levin M.J.,
RA Lorenzi H., Louie T., Machado C.R., McCulloch R., McKenna A., Mizuno Y.,
RA Mottram J.C., Nelson S., Ochaya S., Osoegawa K., Pai G., Parsons M.,
RA Pentony M., Pettersson U., Pop M., Ramirez J.L., Rinta J., Robertson L.,
RA Salzberg S.L., Sanchez D.O., Seyler A., Sharma R., Shetty J., Simpson A.J.,
RA Sisk E., Tammi M.T., Tarleton R., Teixeira S., Van Aken S., Vogt C.,
RA Ward P.N., Wickstead B., Wortman J., White O., Fraser C.M., Stuart K.D.,
RA Andersson B.;
RT "The genome sequence of Trypanosoma cruzi, etiologic agent of Chagas
RT disease.";
RL Science 309:409-415(2005).
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:EAN88989.1}.
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DR EMBL; AAHK01000798; EAN88989.1; -; Genomic_DNA.
DR RefSeq; XP_810840.1; XM_805747.1.
DR AlphaFoldDB; Q4D8Z5; -.
DR SMR; Q4D8Z5; -.
DR STRING; 353153.Q4D8Z5; -.
DR PaxDb; 353153-Q4D8Z5; -.
DR EnsemblProtists; EAN88989; EAN88989; Tc00.1047053510351.50.
DR GeneID; 3541719; -.
DR KEGG; tcr:510351.50; -.
DR eggNOG; ENOG502R7YX; Eukaryota.
DR InParanoid; Q4D8Z5; -.
DR OMA; FWPCGHS; -.
DR OrthoDB; 5479648at2759; -.
DR Proteomes; UP000002296; Unassembled WGS sequence.
DR Gene3D; 3.30.40.10; Zinc/RING finger domain, C3HC4 (zinc finger); 1.
DR InterPro; IPR001841; Znf_RING.
DR InterPro; IPR013083; Znf_RING/FYVE/PHD.
DR Pfam; PF13923; zf-C3HC4_2; 1.
DR SUPFAM; SSF57850; RING/U-box; 1.
DR PROSITE; PS50089; ZF_RING_2; 1.
PE 4: Predicted;
KW Coiled coil {ECO:0000256|SAM:Coils};
KW Metal-binding {ECO:0000256|PROSITE-ProRule:PRU00175};
KW Reference proteome {ECO:0000313|Proteomes:UP000002296};
KW Zinc {ECO:0000256|PROSITE-ProRule:PRU00175};
KW Zinc-finger {ECO:0000256|PROSITE-ProRule:PRU00175}.
FT DOMAIN 276..316
FT /note="RING-type"
FT /evidence="ECO:0000259|PROSITE:PS50089"
FT REGION 1..37
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COILED 73..175
FT /evidence="ECO:0000256|SAM:Coils"
FT COILED 363..393
FT /evidence="ECO:0000256|SAM:Coils"
FT COMPBIAS 14..37
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 400 AA; 46124 MW; 1BC636FBF0BD036B CRC64;
MPKKTGGKKK GQSSPDGSEP RKRKNNKKAT MEPRDVDEMQ KLQELLGDEE QPLGVSKKSL
EGLLSLRQPQ ELAVRLAQSL SSLRTRLAEL ELERLNRGSE APGLSNIVAR RAQEKAEKLE
LEIQKTERIT RRLKIMSNLV GRIIRLREKT LTETHTAMEA EVQSLQEKIR VNEELIRERF
VSRVNMLHRY WLWRTLQELG DQTVGWTFEE ELARGPRYRT LGVQNNIVSE TLEQQLSWLL
VFAEKEKIFR EHVRRLELLV EELTDINDAL EEALTCRVCG LLFEDPVLFW PCGHVFCLVC
FDTLSIAPSL FRCPTCGSIG SEGYVHNLLI AESVAKWMFK DAGYGDIHGA LSLIRLHLSK
FRKEVISSRV AQLRQQLTEA RQKETKVEEL SQMDITYRDF
//
