ID Q4DC35_TRYCC Unreviewed; 167 AA.
AC Q4DC35;
DT 13-SEP-2005, integrated into UniProtKB/TrEMBL.
DT 13-SEP-2005, sequence version 1.
DT 27-MAR-2024, entry version 93.
DE RecName: Full=DNA-directed RNA polymerase III subunit RPC10 {ECO:0000256|ARBA:ARBA00020093};
DE AltName: Full=RNA polymerase III subunit C11 {ECO:0000256|ARBA:ARBA00029985};
GN ORFNames=Tc00.1047053511291.120 {ECO:0000313|EMBL:EAN90096.1};
OS Trypanosoma cruzi (strain CL Brener).
OC Eukaryota; Discoba; Euglenozoa; Kinetoplastea; Metakinetoplastina;
OC Trypanosomatida; Trypanosomatidae; Trypanosoma; Schizotrypanum.
OX NCBI_TaxID=353153 {ECO:0000313|EMBL:EAN90096.1, ECO:0000313|Proteomes:UP000002296};
RN [1] {ECO:0000313|EMBL:EAN90096.1, ECO:0000313|Proteomes:UP000002296}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=CL Brener {ECO:0000313|EMBL:EAN90096.1,
RC ECO:0000313|Proteomes:UP000002296};
RX PubMed=16020725; DOI=10.1126/science.1112631;
RA El-Sayed N.M., Myler P.J., Bartholomeu D.C., Nilsson D., Aggarwal G.,
RA Tran A.N., Ghedin E., Worthey E.A., Delcher A.L., Blandin G.,
RA Westenberger S.J., Caler E., Cerqueira G.C., Branche C., Haas B.,
RA Anupama A., Arner E., Aslund L., Attipoe P., Bontempi E., Bringaud F.,
RA Burton P., Cadag E., Campbell D.A., Carrington M., Crabtree J., Darban H.,
RA da Silveira J.F., de Jong P., Edwards K., Englund P.T., Fazelina G.,
RA Feldblyum T., Ferella M., Frasch A.C., Gull K., Horn D., Hou L., Huang Y.,
RA Kindlund E., Klingbeil M., Kluge S., Koo H., Lacerda D., Levin M.J.,
RA Lorenzi H., Louie T., Machado C.R., McCulloch R., McKenna A., Mizuno Y.,
RA Mottram J.C., Nelson S., Ochaya S., Osoegawa K., Pai G., Parsons M.,
RA Pentony M., Pettersson U., Pop M., Ramirez J.L., Rinta J., Robertson L.,
RA Salzberg S.L., Sanchez D.O., Seyler A., Sharma R., Shetty J., Simpson A.J.,
RA Sisk E., Tammi M.T., Tarleton R., Teixeira S., Van Aken S., Vogt C.,
RA Ward P.N., Wickstead B., Wortman J., White O., Fraser C.M., Stuart K.D.,
RA Andersson B.;
RT "The genome sequence of Trypanosoma cruzi, etiologic agent of Chagas
RT disease.";
RL Science 309:409-415(2005).
CC -!- SIMILARITY: Belongs to the archaeal rpoM/eukaryotic RPA12/RPB9/RPC11
CC RNA polymerase family. {ECO:0000256|RuleBase:RU003474}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:EAN90096.1}.
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DR EMBL; AAHK01000671; EAN90096.1; -; Genomic_DNA.
DR RefSeq; XP_811947.1; XM_806854.1.
DR AlphaFoldDB; Q4DC35; -.
DR STRING; 353153.Q4DC35; -.
DR PaxDb; 353153-Q4DC35; -.
DR EnsemblProtists; EAN90096; EAN90096; Tc00.1047053511291.120.
DR GeneID; 3543016; -.
DR KEGG; tcr:511291.120; -.
DR eggNOG; KOG2906; Eukaryota.
DR InParanoid; Q4DC35; -.
DR OMA; CDSTKAY; -.
DR OrthoDB; 19847at2759; -.
DR Proteomes; UP000002296; Unassembled WGS sequence.
DR GO; GO:0000428; C:DNA-directed RNA polymerase complex; IEA:UniProtKB-KW.
DR GO; GO:0005634; C:nucleus; IEA:UniProt.
DR GO; GO:0003899; F:DNA-directed 5'-3' RNA polymerase activity; IEA:InterPro.
DR GO; GO:0003676; F:nucleic acid binding; IEA:InterPro.
DR GO; GO:0008270; F:zinc ion binding; IEA:InterPro.
DR GO; GO:0006351; P:DNA-templated transcription; IEA:InterPro.
DR CDD; cd10509; Zn-ribbon_RPC11; 1.
DR Gene3D; 2.20.25.10; -; 1.
DR InterPro; IPR001529; DNA-dir_RNA_pol_M/15kDasu.
DR InterPro; IPR012164; Rpa12/Rpb9/Rpc10/TFS.
DR InterPro; IPR034014; Zn_ribbon_RPC11_C.
DR InterPro; IPR001222; Znf_TFIIS.
DR PANTHER; PTHR11239; DNA-DIRECTED RNA POLYMERASE; 1.
DR PANTHER; PTHR11239:SF12; DNA-DIRECTED RNA POLYMERASE III SUBUNIT RPC10; 1.
DR Pfam; PF02150; RNA_POL_M_15KD; 1.
DR Pfam; PF01096; TFIIS_C; 1.
DR SMART; SM00661; RPOL9; 1.
DR SMART; SM00440; ZnF_C2C2; 1.
DR SUPFAM; SSF57783; Zinc beta-ribbon; 1.
DR PROSITE; PS51133; ZF_TFIIS_2; 1.
PE 3: Inferred from homology;
KW DNA-directed RNA polymerase {ECO:0000256|ARBA:ARBA00022478,
KW ECO:0000256|RuleBase:RU003474};
KW Metal-binding {ECO:0000256|ARBA:ARBA00022723,
KW ECO:0000256|RuleBase:RU003474};
KW Reference proteome {ECO:0000313|Proteomes:UP000002296};
KW Signal {ECO:0000256|SAM:SignalP};
KW Transcription {ECO:0000256|RuleBase:RU003474};
KW Zinc {ECO:0000256|ARBA:ARBA00022833};
KW Zinc-finger {ECO:0000256|ARBA:ARBA00022771, ECO:0000256|PROSITE-
KW ProRule:PRU00472}.
FT SIGNAL 1..24
FT /evidence="ECO:0000256|SAM:SignalP"
FT CHAIN 25..167
FT /note="DNA-directed RNA polymerase III subunit RPC10"
FT /evidence="ECO:0000256|SAM:SignalP"
FT /id="PRO_5004236252"
FT DOMAIN 121..165
FT /note="TFIIS-type"
FT /evidence="ECO:0000259|PROSITE:PS51133"
SQ SEQUENCE 167 AA; 19129 MW; 291050337C687F0D CRC64;
MNLAFNSFFF VCVCAAQHIR RAGAHDRSRK RGPPRREQWS RRRSAMFFCP FCGTLLLIEP
HHPTNRFACS SCTYVAPIPS THLLTVNHSL LKFNKTVEDD ANVKANGIKT KNEEVDGGQL
ITVRCQNDEK FCDGNRAHYV QIQMRSADEP ATTFFKCLKC GFQWKQD
//
